Drugs: Mitosis Inhibitors (M phase drugs) Flashcards by Madeline Wing

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drugs ending in -tine or -taxel inhibit what

microtubules

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Vincristine
Vinblastine

prevent polymerization of microtubules (mitotic spindles)

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side effect of Vincristine

neurotoxic

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side effect of Vinblastine

myelosuppression (no neurotoxicity)- bone marrow doesn’t make enough blood cells or platelets

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Paclitaxel
Docetaxel

prevents depolymerization of microtubules (mitotic spindles)

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side effect of paclitaxel and docetaxel

neurotoxic

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Drugs: Mitosis Inhibitors (M phase drugs) Flashcards

(6 cards)