Drugs: Protein Kinase Inhibitors Flashcards by Madeline Wing

{ "@context": "https://schema.org", "@type": "Organization", "name": "Brainscape", "url": "https://www.brainscape.com/", "logo": "https://www.brainscape.com/pks/images/cms/public-views/shared/Brainscape-logo-c4e172b280b4616f7fda.svg", "sameAs": [ "https://www.facebook.com/Brainscape", "https://x.com/brainscape", "https://www.linkedin.com/company/brainscape", "https://www.instagram.com/brainscape/", "https://www.tiktok.com/@brainscapeu", "https://www.pinterest.com/brainscape/", "https://www.youtube.com/@BrainscapeNY" ], "contactPoint": { "@type": "ContactPoint", "telephone": "(929) 334-4005", "contactType": "customer service", "availableLanguage": ["English"] }, "founder": { "@type": "Person", "name": "Andrew Cohen" }, "description": "Brainscape’s spaced repetition system is proven to DOUBLE learning results! Find, make, and study flashcards online or in our mobile app. Serious learners only.", "address": { "@type": "PostalAddress", "streetAddress": "159 W 25th St, Ste 517", "addressLocality": "New York", "addressRegion": "NY", "postalCode": "10001", "addressCountry": "USA" } }

drugs ending in -nib inhibit

protein kinase

How well did you know this?

Not at all

Perfectly

Imatinib

targets BCR-ABL
inhibits tyrosine kinase

How well did you know this?

Not at all

Perfectly

BCR-ABL gene is associated with 2 things:

leukemia
philadelphia chromosome (9 to 22)

How well did you know this?

Not at all

Perfectly

Erlotinib
Gefitinib

[E and G]

inhibition of tyrosine kinase domain of EGFR

How well did you know this?

Not at all

Perfectly

these 2 growth factors promote tumor angiogenesis (formation of new blood vessels)

VEGF and PDGF

How well did you know this?

Not at all

Perfectly

Dabrafenib

VEGF/PDGF receptor blocker
Ras/MEK inhibitor
blocks MAPK pathway

How well did you know this?

Not at all

Perfectly

Drugs: Protein Kinase Inhibitors Flashcards

(6 cards)