Dynamics Resistance to Flow Flashcards

1
Q

what is flow equal to?

A

change in pressure divided by resistance….think about it more pressure pushing helps but more resistance makes it harder to go down

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2
Q

in laminar flow, what provides resistance?

A

the walls of the tube

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3
Q

in laminar flow, what is the change in pressure proportional to?

A

the velocity of flow

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4
Q

in turbulent flow, what is the change in pressure proportional to?

A

the velocity of flow squared

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5
Q

what parts of the respiratory tract have turbulent flow?

A

the trachea and mainstem bronchi

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6
Q

what parts of the respiratory tract have transitional flow?

A

most of the bronchial tree

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7
Q

what parts of the respiratory tract have laminar flow? why is this?

A

the small airways…bc the cross sectional area is so high

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8
Q

what is the relationship between resistance and radius of the tube?

A

resistance is inversely proportional to radius to the 4th power…halving the radius raises the resistance to the 16th

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9
Q

does cross sectional area increase or decrease as you move down the respiratory tract?

A

INCREASE

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10
Q

does resistance increase or decrease with expiration? what about inspiration?

A

resistance increases during expiration and decreases during inspiraition

increase due to smaller radius in small airways
decrease due to increasing radius in small airways

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11
Q

on a flow volume loop, when a forced exhalation occurs…explain what the curve looks like and why it is this shape?

A

the curve is initially sharply increasing then it peaks and has a smaller decreasing slope because the airways are getting more resistance and recoil is running the show not muscles

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12
Q

describe how the alveolus pressure changes as you begin forced expiration and transition from end inspiration

A

the pressure raises from 0 to about 30 and is driving the air out

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13
Q

what happens when the intrapleural pressure overcomes the pressure in the airways during expiration?

A

the airways collapse

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14
Q

what causes the decrease in pressure during expiration? what can this cause?

A

resistance of the airways as they are becoming smaller is increasing…this can lead to airway collapse if pressure becomes smaller than intrapleural pressure

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15
Q

what are the two phases of forced expiration?

A

effort dependent and effort independent

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16
Q

in effort dependent forced expiration, where does the pressure of intrapleural cavity overcome the pressure in the airways?

A

this is in bronchus/trachea so you do not get collapse in effort dependent forced expiration

17
Q

in effort independent forced expiration, where does the intrapleural cavity pressure overcome the pressure in the airway? what happens?

A

this is in the smaller airways like bronchioles and can lead to airway collapse…the resistance of the small vessels is dropping the pressure faster and leads to their collapse

18
Q

what is the driving force of expelling air in effort independent phase?

A

elastic force of the lung

19
Q

why are alveoli tethered to small airways?

A

they help keep them open during expiration and avoid collapsing

20
Q

do obstructive lung breathers breath at higher or lower than normal volumes?

A

higher volumes to help overcome the resistance of the tightened airways

21
Q

do restrictive lung breathers breath at higher or lower than normal volumes?

A

breath at lower volumes because of less recoil

22
Q

do obstructive or restrictive flow/volume curves have a scooped out appearance during expiration? why?

A

obstructive…because airways are collapsing so much quicker due to the increased resistance

23
Q

what is the FEV?

A

forced expiratory volume in 1 second

24
Q

what is the FVC?

A

forced vital capacity

25
what is FEV/FVC?
this is the percentage of the forced vital capacity that one can expel in forced expiration
26
what is the normal value for FEV/FVC?
80%..some say 70% (4/5L)
27
is the FEV/FVC higher or lower in obstructive lung disease?
lower...because of the quick collapse of airways 40%
28
is the FEV/FVC higher or lower in restrictive lung disease?
higher...close to 90% but this is less volume relatively
29
what is the FEF25-75 value representative of in forced expiration?
middle 50% of the FEV more refelctive of the smaller airways
30
why are the small airways called the silent zone when it comes to obstructive pulmonary disease?
because they barely contribute to the overall resistance of the flow...the flow experiences most of its resistance in the upper airways
31
in forced expiration, how high can you raise intrapleural pressure?
close to 100 cmH2O
32
do restrictive and obstructive lungs have higher or lower maximum flow rates than
lower