E01_02 Drug Interactions and Pharmacovigilance

Question 1

2017, 2018_Drug Interactions and Pharmacovigilance

The scope of pharmacovigilance covers the following areas of adverse effects of drugs except?

A. Assessment
B. Prevention
C. Treatment
D. Understanding

Answer 1

C. Treatment

Also Detection

Question 2

2017_Drug Interactions and Pharmacovigilance

The reasons why premarketing trials cannot predict problems in drug prescribing is/are?

A. The effects of concomitant diseases and drugs are not normally studied.

Answer 2

A. The effects of concomitant diseases and drugs are not normally studied.

Question 3

2017, 2018_Drug Interactions and Pharmacovigilance

Aim of pharmacovigilance covers the following:

A. Improvement of patient care and safety.
B. Cost effectiveness of drug prescribing
C. Effective communication to general public.
D. All of the above

Answer 3

D. All of the above

Question 4

2017_Drug Interactions and Pharmacovigilance

The following statements is/are true of drug interactions:

B. These are interactions that can increase or decrease a drug’s efficacy.

Answer 4

B. These are interactions that can increase or decrease a drug’s efficacy.

Question 5

2018_Drug Interactions and Pharmacovigilance

According to RA 8203, a counterfeit drug means

A. An imported drug that is not registered in the country
B. A medicinal product that has the correct ingredients but insufficient amount
C. A medicine that has the wrong constituents
D. AOTA

Answer 5

D. AOTA

Question 6

2017_Drug Interactions and Pharmacovigilance

Medication errors cover the following events:

C. Product labeling and nomenclature

Answer 6

C. Product labeling and nomenclature

Question 7

2017_Drug Interactions and Pharmacovigilance

Off label drug use can be motivated by:

A. Life threatening medical condition.
B. If pathologic/physiologic function of 2 diseases are similar.
C. Drugs not studied/approved for specific populations
D. All of the above

Answer 7

D. All of the above

Question 8

2017_Drug Interactions and Pharmacovigilance

Based on the FDA advisory 2013-035 on treatment modalities outside standard medical care:

B. Food supplements without scientific basis are not considered standard of care.

Answer 8

B. Food supplements without scientific basis are not considered standard of care.

Question 9

2017_Drug Interactions and Pharmacovigilance

Morbidity and mortality from poisoning cases can provide the following information:

A. Misuse and abuse of drugs
B. Counterfeit drugs
C. Substandard drugs
D. Adverse reactions

Answer 9

A. Misuse and abuse of drugs

Question 10

2017_Drug Interactions and Pharmacovigilance

Direct pharmacodynamic drug interaction includes the following:

C. Drug-receptor reactions

Answer 10

C. Drug-receptor reactions

Question 11

2017_Drug Interactions and Pharmacovigilance

The object drug has the following property/ies:

C. Low toxic/therapeutic ratio.

Answer 11

C. Low toxic/therapeutic ratio.

Question 12

2017_Drug Interactions and Pharmacovigilance

Pharmaceutical drug interactions include the ff:

A. IV drug incompatibilities
B. Drug-container interaction
C. Drug-excipient interaction
D. All of the above.

Answer 12

D. All of the above

Question 13

2017_Drug Interactions and Pharmacovigilance

Increasing awareness among clinicians on drug safety can be achieved through:

A. Access to reliable information
B. Communication with health professionals
C. Linking clinical findings with health policy
D. All of the above

Answer 13

D. All of the above

Question 14

2017_Drug Interactions and Pharmacovigilance

The following is true of the effects brought about by drug interaction:

C. Potentiation means that the activity of one drug is increased by another drug that does not have the same activity.

Answer 14

C. Potentiation means that the activity of one drug is increased by another drug that does not have the same activity.

Question 15

2017_Drug Interactions and Pharmacovigilance

Strategy/ies to avoid adverse drug interaction includes the following:

B. Be particularly careful when you prescribe to children, pregnant patients, elderly etc.
C. Review your patient regularly for all the drugs used.
D. All of the above

Answer 15

D. All of the above

Question 16

2016_Drug Interaction and Pharmacovigilance

Aim of pharmacovigilance includes the following:

A. To provide guidelines for treatment
B. To promote personal and public health safety
C. To address medicolegal aspects
D. All of the above

Answer 16

B. To promote personal and public health safety

Question 17

2016_Drug Interaction and Pharmacovigilance

Precipitant drug:

A. Low toxic therapeutic ratio
B. Enhances metabolism of other drugs
C. Low protein binding capacity
D. Narrow margin of safety

Answer 17

B. Enhances metabolism of other drugs

Question 18

2016_Drug Interaction and Pharmacovigilance

Factors involved in distribution drug-drug interactions is/are

A. Relative binding affinity of the drug
B. Altered transport mechanism
C. Competition for tubular secretion
D. All of the above

Answer 18

A. Relative binding affinity of the drug

B - absorption
C - excretion

Question 19

2016_Drug Interaction and Pharmacovigilance

Physiologic pharmacodynamic interaction involves

A. Container-drug interaction
B. Side effect of the drug influencing effect of object of drug
C. Agonist-antagonist interaction
D. Interactions due to different cellular mechanisms

Answer 19

D. Interactions due to different cellular mechanisms

A. Container-drug interaction&raquo_space; Pharmaceutical
B. Side effect of the drug influencing effect of object of drug&raquo_space; Pharmacodynamic, Indirect
C. Agonist-antagonist interaction&raquo_space; Pharmacodynamic, Direct, Pharmacologic