EAS Flashcards

(88 cards)

1
Q

Filaggrin binds ___

A

Keratin

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2
Q

Free ribosomes generally make proteins that will be ___ while the RER ribosomal components make proteins that will be ___

A

imported, exported

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3
Q

Nucleolus location and two main functions

A

Inside Nuc.; rRNA transcription & maturation/assembly of ribosomes.

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4
Q

COPI proteins use KDEL receptors to

A

Package vesicles in the retrieval cis pathway back to ER

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5
Q

At the end of the ___ week the embryo has the flat disc

A

3rd

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6
Q

The ___ stain visualizes the nucleus with a blue dye and a positive charge (so it stains negative structures) For LM

A

Hematoxylin (H)

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7
Q

Somatopleuric Mesoderm

A

gives rise to inner lining of body wall and parts of limbs

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8
Q

Stratified Epithelium

A

MORE than one layer WITHOUT intervening basement membrane

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9
Q

Ribosomes are made in the___

A

Nucleolus

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10
Q

Vesicles that have the ___ Marker will be segregated to the lysosomal pathway

A

Mannose 6 phosphate M6P

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11
Q

The primary endoderm cells (hypoblast) migrate over the inner surface of ___ and differentiate into ___ which secrete an extracellular matrix.

A

Cytotrophoblasts, Extraembryonic Endoderm

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12
Q

The Corpus Luteum secretes ___ until middle of first trimester. Then chorion secretes the ___ (same answer)

A

Progesterone

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13
Q

Two classifications of Secretory portion

A

Tubular or Acinar

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14
Q

Euchromatin stains ___ and is transcriptionally ____

A

Lighter, Active

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15
Q

The trophoblast secretes ___ which feeds back and supports the survival of corpus luteum

A

Humn Chorionic Gonadotropin (hCG)

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16
Q

The Zonula Adherens, or intermediate junctions, are found ___ the Zonula occuldens

A

Below

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17
Q

Gap junctions are composed of ___ proteins and allow cell-cell communication

A

Connexin

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18
Q

The outer surface of the nuclear envelope often contains _____ and is continuous with the ___

A

Ribosomes, RER

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19
Q

COPII proteins

A

Package vesicles in the forward trans direction towards the membrane

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20
Q

Claudin and Occludin are two proteins that compose _____

A

Tight Junctions

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21
Q

Special Antigen presenting cells found in Stratum Spinosum

A

Langerhans’ Cells (Dendritic (star-shaped) cells

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22
Q

Lateral Plate Mesoderm

A

contributes to body wall and digestive tract

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23
Q

The copper-containing enzyme, ___ converts ___ to Melanin

A

Tyrosinase, Tyrosine

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24
Q

Apocrine

A

Top portion of cell release

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25
RU486 is a ____ inhibitor to the hormone ___ to promote menses
Competitive, Progesterone
26
The three layers of the enometrium are:
1. Compact Layer 2. Spongy Layer 3. Basal Layer
27
Partial hydatiform Moles are caused by ___ karyotype
Triploid
28
Merocrine
Vesicular release
29
The Nucleolonema consists of the ___ and the ___ but not the _______
Pars Fibrosa and Pars Granulosa, NOT the Pars Amorpha
30
Glycogen can be identified by its lack of ___
Membrane
31
Myoepithelial cells
Facilitate secretions in the secretory portion of sweat glands
32
Eight Locations for Ectopic Pregnancy
1. Fimbrial 2. Ampullary 3. Isthemic 4. Ovarian 5. Interstitial 6. Cervical 7. Abdominal 8. Rectouterine Pouch
33
Where is Keratyoyalin and Lamellar Granules found?
Stratum Granulosum
34
The _____ cells form both the embryonic mesoderm and the extraembryonic mesoderm
Epiblast
35
A___ microscope has a 1-1.45nm Resolution with 500,000x and Up magnification
TEM
36
The ER performs 1. Cleavage of ____ 2. Facilitates proper ____ 3. Attaches ___ to maturing proteins 4. SER synthesizes __,__,___ 5. Contains enzymes to ___
``` Signal Peptides Protein Folding Oligosaccharides Lipids, Steroids, Fats Detox drugs ```
37
The _____ is made up of Type IV collagen, glycoproteins, laminin, entactic and heparin sulfate AND it is where Cells lie
Basal Lamina
38
Lower wavelengths correspond with ___ resolution, think electron vs light microscope
Better
39
The ____ Layer of the Dermis contains loose connective tissue, extensive capillary network, and nerve endings that are free and encapsulated as seen in Meissners' corpuscles
Papillary
40
Telogen Phase
Resting phase; Club hair is final hair product
41
Two classifications of Ducts
Simple/Unbranched or Compound/Branched
42
Women with pre-eclampsia have an increase in ___ and a decrease of ___, therefore flooding the mother with (answer 2) alleviates the problem
sFLT-1, PLGF, PLGF
43
The ___ uses Heuser's membrane, Extraembryonic Ret, and ECM cytotrophoblast cells to migrate
Extraembryonic Mesoderm
44
The gradual rise of what hormone leads to the LH and FSH surge?
Estrogen
45
The grainy area where maturing ribosomal subunits are found
Pars Granulosa (PG)
46
___ Forming outer layer of yolk sac is major site of Hematopoesis
Extraembryonic Mesoderm
47
Nuclear lamins, cells of mesenchymal origin, muscle cells, glial cells, keratins are all __________
Intermediate filaments
48
Complete Hydatiform Moles' Chromosomes are completely derived from which parent?
The Father
49
The Krebs cycle occurs in the ___ of the mitochondria
Matrix
50
___ is used to stain and visualize sugar residues like glycogen and glycoproteins For LM
Periodic Acid Schiff
51
Hair Anagen phase
Growth; proportionate to anagen
52
Intermediate Mesoderm
Located lateral to the paraxial mesoderm, Gives rise to the Urinary system and parts of the reproductive system
53
The two portions of a gland
Duct and Secretory
54
Hair Catagen phase
Regression; Apoptosis of Keratinocytes
55
The four basic tissue types:
- Nervous - Epitheilial - Muscle - Connective
56
Heterochromatin stains____ and is transcriptionally ____
Darker, Inactive
57
The Stratum___ is seen only in thick skin
Lucidum
58
Holocrine
Entire cell released
59
The basement membrane has the stronger proteins to anchor the cell called ____
Integrins
60
A ___ microscope has a 2nm Resolution and 100,000x and up Mag
Scanning
61
A ___ microscope has 0.2uM rseolution and up to 1500x magnification
Light
62
_____ bind to chromatin of non-dividing cells and are found in the inner surface of the nuclear envelope (facing the inside)
Lamina Proteins
63
The ___ layer is the deeper area of the dermis contains dense iregular connective tissue, Rich with Arteriovenous AV shunts, Have pacinian corpuscles, and smooth muscle bundles to insert hair follicles
Reticular
64
Splanchnopleuric Mesoderm
gives rise to covering of viscera
65
Basal Lamina and Lamina reticularis make the ___
Basement membrane
66
The Hair ___ is dermal connective tissue essential for induction and maintenance of hair follicle which supplies blood and nerves. Development and cycling is depending on these!!
Papilla
67
___ builds around Heuser's membrane and provides a space for Extraembryonic mesoderm formation
Extraembryonic Reticulum
68
Part of epidermis responsible for nail formation
Nail Matrix
69
Simple Ethilium
One layer of cells
70
The mis-shapen nucleolar organizer region
Pars Amorpha (PA)
71
Transport proteins known as exportins and importins bind to the _____ to regulate movement.
Nuclear Pore complex
72
Paraxial Mesoderm
gives rise to Somitomeres; precursors to somites which segment the vertebral column
73
The thread-like area that creates rRNA transcripts
Pars Fibrosa (PE)
74
____ is a syndrome recognized by shallow implantation
Pre-eclampsia
75
Three types of cell shapes
Squamous-Flat Cuboidal-Cube-like Columnrar-Column-like
76
The Duct portion of sweat glands
The Re-absorption of Na, K, Cl opens directly on a sweat pore
77
The Unfertilized egg cells are lock in the ______ of the cell cycle
Second Meitoic Metaphase
78
The nuclear envelope has ___ (how many) membranes
Two
79
New proteins have a ___ at its N-terminus which binds to a ___ to temporarily stop elongation and allow the complex to bind to a receptor on the outer surface o the ER. This allows the protein to be translocated through the ER membrane into the ER lumen to be modified.
Signal Peptide, Signal Recognition Particle.
80
Out of Prokaryotes, Archaea, and Eukaryotes, which of these have membrane bound organelles?
Eukaryotes
81
Prechordal Plate Mesoderm
Induces midline structures such as brain;
82
Inermediate junctions are mediated by ___ proteins
Cadherin
83
The two skin layers which have mitotic activity are:
Stratum Basale(Germinativum) and Stratum Spinosum
84
The sweat glands' secretory portion may consist of either ___ cells which contain glycoprotein granules or ___ which have no granules and are essential for ion and water transport.
Dark, Clear
85
The ___ stain visualizes the cytoplasm with a pink dye and a negative charge (so it stains positive structures) For LM
Eosin (E)
86
Aldehyde Fuschin
Elastic Fibers
87
Orcein
Collagen Fibers
88
Silver
Golgi Apparatus, Reticular Fibers