Embryogenesis and development Flashcards

1
Q

What is the difference between determinate and indeterminate cells?

A

Determinate cells have already been designated to turn into a type of cell

Indeterminate cells haven’t been designated yet, so they have the ability to become any part of the organism

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2
Q

What are the characteristics of the morula?

A

Just a mass of cells the looks like a berry

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3
Q

What are the characteristics of the blastula?

A

A hollow ball of cells with fluid inside, consists of the trophoblast and inner cell mass

The inner cell mass will become the embryo and the trophoblast will become the chorion

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4
Q

What are the characteristics of the gastrula?

A

This is when the three germ layers form

An invagination of the blastula results in one side of the cell caving in until it touches the other side of the cell, making the tube (anus in humans)

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5
Q

The ability of one cell to influence nearby cells is called _____

A

Induction

(cells that create induction are called inducers)

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6
Q

The umbilical cord has ___ artery (ies) and ___ vein(s)

A

2 arteries
1 vein

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7
Q

What is the ectoderm and what are some structures it makes up?

A

The outer most layer

Many “outer” structures:
hair, nails, inner ear, nervous system, eye lens, lower anus, epidermis

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8
Q

What is the mesoderm and what are some structures it makes up?

A

The middle layer

Musculoskeletal system, muscular and connective tissue, layers of digestive and respiratory system, adrenal cortex

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9
Q

What is the endoderm and what are some structures it makes up?

A

The inner most layer

Epithelial lining of digestive and respiratory system, pancreas, thyroid, bladder, distal urinary tract, parts of the liver

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10
Q

How does neurulation occur?

A

The notochord (made of mesoderm) forces the ectoderm to start folding inward, forming the neural folds. Eventually the neural folds become the neural tube

Then the crest cells migrate out and become the peripheral nervous system

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11
Q

The notochord is made of _____ while the nervous system is made of ____

A

Mesoderm

Ectoderm

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12
Q

Explain how the three stages of development (specification, determination, differentiation) occur

A

Specification is reversible and is the point where cells are designated to become a certain type

Determination is irreversible and occurs when the cells have been committed to a certain type, but haven’t undergone any changes yet

Differentiation occurs when the cell changes it’s structure, function and biochemistry to match the cell type

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13
Q

Stem cells are those that have not ____

A

Undergone differentiation, or have the ability to give rise to other cells

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14
Q

Totipotent cells

A

Have the highest level of potency

They’re still in the morula phase, so they can become literally anything

Found from fetal stem cells

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15
Q

Pluripotent cells

A

Have the middle level of potency

They’ve already reached the gastrula stage (differentiated into germ layers) so they can become anything other than placental cells

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16
Q

Multipotent cells

A

Have the lowest level of potency (adult stem cells)

Can become multiple cells within a certain group. The class they’re in has already been decided (ex: immune cells) so they can only be used to create cells of that same category

17
Q

Autocrine

A

Acts on the same cell that secreted the signal

18
Q

Endocrine

A

Travels through the blood is reach the target cells

19
Q

Juxtacrine

A

Acts directly on adjacent cells, does not work through diffusion

20
Q

Paracrine

A

Works on nearby cells through diffusion

21
Q

What is the difference between complete and incomplete regeneration?

A

Complete regeneration occurs when the newly formed tissue is identical to the original

Incomplete regeneration occurs when the newly formed tissue is different than the original (ex: scar tissue)

22
Q

Why would cells need to migrate?

A

So they’re able to reach the necessary location for their designated purpose

23
Q

Senescence

A

Normal cell aging (this kind of cell will eventually hit apoptosis)

24
Q

In what trimester does most organ development occur?

A

First

25
Q

The ____ are the last organ to develop

A

Lungs

26
Q

The foramen ovale and ductus arteriosus shunt blood away from the ____

A

Lungs

27
Q

What is the purpose of the placenta?

A

Exchanges gas, nutrients, and waste

Gets necessary things from mother so fetal and maternal blood don’t have to mix (these two cannot mix)

28
Q

The ductus venosus shunts blood away from the ____

A

Liver

29
Q

The most fetal movement occurs during the ____

A

Second trimester

30
Q

Antibody transfer occurs at the highest rate in the ____ trimester

A

Third trimester