End of chapter questions (2)

Question 1

Digestion of bacteria

Answer 1

Second

Question 2

Increase in chemoattractants at site of tissue damage

Answer 2

Fourth

Question 3

Ingestion of bacteria

Answer 3

Third

Question 4

Change in direction of movement due to a chemoattractant substance

Answer 4

First

Question 5

The function of polymorphonuclear neutrophil (PMN) leukocytes is:

Answer 5

Primary phagocytic cells

Question 6

Mast cells are associated with

Answer 6

Participation in IgE hypersensitivity reactions

Question 7

Chronic granulomatous disease represents a defect of

Answer 7

Oxidative metabolism

Question 8

An alteration of phagocytic killing is associated with

Answer 8

Corticosteroid therapy

Question 9

Mast cells have:

Answer 9

High concentration of histamine in the granules

Question 10

Cell mediated immune response associated with humoral immunity

Answer 10

Defense against viral and bacterial infection
Defense against fungal and bacterial infection
Antibody production

Question 11

T cell functions

Answer 11

Mediation of delayed-hypersensitivity reactions
Mediation of cytolytic reactions
Regulation of the immune response

Question 12

T cell response is associated with

Answer 12

Cellular immune response

Question 13

The function of B cells is

Answer 13

Humoral response

Question 14

NK function

Answer 14

Antibody-dependent, cell-mediated cytotoxicity (ADCC) reaction

Question 15

NK cells mediate

Answer 15

viral immunity

Question 16

Surface membrane marker for CD4

Answer 16

Helper-inducer T cells

Question 17

The surface membrane marker for CD8 is

Answer 17

Suppressor-cytotoxic T cells

Question 18

Surface membrane marker for CD3 is

Answer 18

All or most T lymphocytes

Question 19

The process of aging causes the thymus to

Answer 19

Decrease in size
Lose cellularity

Question 20

T lymphocytes can also be referred to as

Answer 20

Memory cells

Question 21

T lymphocyte characteristics

Answer 21

Can form a suppressor-cytotoxic subset
Can be helper-inducers
Can be CD4+ or CD8+

Question 22

T lymphocyte immune response it’s associated with

Answer 22

Cellular immune response

Question 23

B lymphocytes are associated with what immunity

Answer 23

Humoral antibody response

Question 24

The appropriate function of cytotoxic or effector T cells is related to/associated with

Answer 24

Directly destroying target cells
Transplanted organ rejection
CD4+ marker

Question 25

Regulator T cell function

Answer 25

Activate macrophages Stimulate cell growth and differentiation Antibody production and secretion of cytokines

Question 26

The complement system is

Answer 26

A heat-labile series of plasma proteins Composed of many proteinases Composed of three interrelated pathways

Question 27

All of the following are complement-controlling proteins except: C1 (INH) Factor I Factor H C3

Answer 27

C3

Question 28

The three complement activation pathways converge at the point of cleavage of complement component

Answer 28

C3

Question 29

All of the following result from complement activation except: Decreased cell susceptibility to phagocytosis Blood vessel dilation and increased vascular permeability Production of inflammatory mediators Cytolysis or hemolysis

Answer 29

Decreased cell susceptibility to phagocytosis

Question 30

Which complement component is present in the greatest quantity in plasma

Answer 30

3

Question 31

Classic complement activation sequence

Answer 31

C1 to C4 to C2 to C3 to C5 to C6789

Question 32

Arrange the three stages of the classic complement pathways in the correct sequence

Answer 32

Recognition Enzymatic activation Membrane attack

Question 33

At what stage does the complement system reach its full amplitude

Answer 33

C3

Question 34

What makes up the membrane attack complex

Answer 34

C5b6789

Question 35

The final steps (C8 and C9) in complement activation lead to

Answer 35

Cell lysis

Question 36

Activation by antigen-antibody complexes represents

Answer 36

Classic pathway

Question 37

Generation of an active (C3b, Bb) C3 convertase is seen in

Answer 37

Alternative pathway

Question 38

Activation by microbial and mammalian cell surfaces occurs in

Answer 38

Alternative pathway

Question 39

The ____ terminates in a membrane attack complex

Answer 39

Classic and alternative pathway

Question 40

The alternative complement pathway is (can be):

Answer 40

Considered to be a predominantly, non-antibody-initiated pathway Activated by factors such as endotoxinbs