Module 5 EoC Questions

Question 1

Common vectors of Lyme disease include all of the following except:

I. pacifucus
I. scapularis
I. ricinus
D. variabilis

Answer 1

D. variabilis

Question 2

The only continent without lyme disease is

Answer 2

Antarctica

Question 3

The primary reservoir in nature for B. burgdorferi

Answer 3

white-footed mouse

Question 4

The first B. burgdorferi antigen to elicit an antibody response is

Answer 4

flagellar 41-kDa polypeptide

Question 5

Erythema chronicum migrans (ECM)

Answer 5

Harbors B. burgdorferi in the advancing edge

Question 6

The predominant symptoms of Lyme meningitis are

Answer 6

severe headache and mild neck stiffness

Question 7

The most useful test for distinguishing between true positive and false positive serologic test results in lyme disease is

Answer 7

polymerase chain reaction

Question 8

Lyme disease prevention methods include all of the following except:

wearing light-colored clothes
tucking pants into socks
applying insect repellent to skin and clothes
all of the above

Answer 8

All of the above

Question 9

Lyme disease, the most common ttick-borne disease in the United States, is a major health hazard for:

dogs
horses and cattle
humans
all of the above

Answer 9

all of the above

Question 10

lyme disease is a ___ type of infection

Answer 10

bacterial

Question 11

Unlike some procedures, the polymerase chain reaction assay can be used to detect lyme disease-causing organisms in

Answer 11

synovial

Question 12

Antigen detection systems in Lyme disease testing screen for ____ rather than for ____ associated with the infection

Answer 12

antigenic products (1)

antibody (2)

Question 13

A patient who has a specific Lyme disease-associated manifestation may be treated with

Answer 13

antibiotic

Question 14

West Nile virus causes

Answer 14

encephalitis

Question 15

A type 1 hypersensitivity reaction is a

Answer 15

anaphylactic reaction

Question 16

A type 2 hypersensitivity reaction is a

Answer 16

cytotoxic reaction

Question 17

A type 3 hypersensitivity reaction is a

Answer 17

immune complex reaction

Question 18

A type 4 hypersensitivity reaction is a

Answer 18

cell-mediated reaction

Question 19

with which cell type are anaphylactic reactions associated

Answer 19

mast

Question 20

type 3 reactions are exemplified by all of the following except:

arthus reaction
serum sickness
glomerulonephritis
shingles

Answer 20

shingles

Question 21

Type 4 reactions are responsible for all of the following except:

contact sensitivity
delayed hypersensitivity
elimination of tumor cells bearing neoantigens
hemolysis of red blood cells

Answer 21

hemolysis of red blood cells

Question 22

Type 1 hypersensitivity reactions can be associated with:

food allergies
hay fever
asthma
all of the above

Answer 22

all of the above

Question 23

The most common agents that cause anaphylactic reactions are

Answer 23

drugs and insect stings

Question 24

An example for a delayed nonhemolytic (type 2 hypersensitivity) reaction is

Answer 24

graft-versus-host disease

Question 25

All of the following characteristics are common to organ-specific and organ-nonspecific disorders except: autoantibody tests are of diagnostic value antibodies may appear in each of the main immunoglobulin classes antigens are available to the lymphoid system in low concentrations circulatory autoantibodies react with normal body constituents

Answer 25

antigens are available to the lymphoid system in low concentrations

Question 26

antibody expression in the development of autoimmunity is regulated by all of the following factors except: genetic predisposition increasing age environmental factors active infectious disease

Answer 26

active infectious disease

Question 27

the mechanisms responsible for autoimmune disease is

Answer 27

circulating immune complexes

Question 28

one of the mechanisms of self-tolerance is

Answer 28

elimination of self-reactive immature lymphocytes

Question 29

A characteristic associated with anticardiolipin antibody is

Answer 29

present in SLE and associated with arterial and venous thrombosis

Question 30

A characteristic associated with anti-DNA antibodies is

Answer 30

useful in monitoring the activity and exacerbations of SLE

Question 31

The term autoimmune disease is used when demonstrable immunoglobulins display specificity for self antigens cytotoxic T cells display specificity for self antigens cytotoxic t cells contribute to the pathogenesis of the disease all of the above

Answer 31

all of the above

Question 32

a description of antinuclear antibody (ANA) is

Answer 32

a characteristic of untreated systemic lupus erythematosus

Question 33

SLE is more common in

Answer 33

adolescent through middle-aged women

Question 34

one of the most potent inducers of abnormalities and clinical manifestations of SLE is

Answer 34

procainamide hydrochloride

Question 35

The principal demonstrable antibody in SLE is antibody to

Answer 35

nuclear antigen

Question 36

SLE is a classic model of autoimmune disease and is a(n): abnormality of the joints systemic rheumatoid disorder abnormality of connective tissue all of the above

Answer 36

all of the above

Question 37

The overall incidence of SLE has an increased frequency among: african americans native americans puerto ricans all of the above

Answer 37

all of the above

Question 38

patients with SLE characteristically manifest

Answer 38

butterfly rash over the bridge of the nose

Question 39

Laboratory features of SLE include: the presence of ANAs circulating anticoagulant and immune complexes decreased levels of complement all of the above

Answer 39

all of the above

Question 40

Laboratory procedures that are helpful in assessing renal disease include: antibody to double-strand DNA levels of C3 and C4 cryoglobulin assay all of the above

Answer 40

all of the above

Question 41

The ANA staining of a diffused or homogenous pattern is associated with

Answer 41

anti-dna-nucleoprotein antibody

Question 42

the ANA staining of a speckled pattern is associated with

Answer 42

antibody to any extractable nuclear antigen devoid of DNA or histone

Question 43

Rheumatoid arthritis most frequently develops in

Answer 43

middle-aged women

Question 44

rheumatoid factor is defined as

Answer 44

antibodies with specificity for antigen determinants on of Fc fragment of human or certain animal IgG

Question 45

The principle of the rapid agglutination test is based on the reaction of patient ___ and ___ derived from gamma globulin

Answer 45

antibody antigen

Question 46

Criteria for the diagnosis of rheumatoid arthritis include morning stiffness rheumatoid nodules radiographic changes all of the above

Answer 46

all of the above

Question 47

RF correlates with all of the following except: the severity of the disease in general the presence of nodules other organ system involvement the age of the patient

Answer 47

the age of the patient