Flashcards in Endo Drugs Deck (29)
What is orlistat? What does it improve?
pancreatic lipase inhibitor
improves BP and lipid profiles
What reduces glucose absorption from the gut by preventing complex sugars from getting broken down? When to be given?
What is pioglitazone? Why is this bad but good?
can take up to 12 wks to work but improved lipid profiles
What is Exenatide? How is it given?
increases insulin ONLY when glucose is elevated
What drug is insulin sensitizer on liver and muscle cell? Why is this drug good for DMII? Contraindicated in?
Which drugs increase insulin secretion? Is it sulfo or nonsulfonylureas?
Glipizide - sulfonylurea
What insulin is long acting? Onset? Duration?
What insulin is intermediate acting? Onset? Duration?
NPH, isophane insulin
2-4hr; duration 10-16hr
What insulin is short acting? Onset?
What are the 2 rapid acting insulin? Onset?
Pt has initial a1c >9 -tx?
no sx: dual or triple therapy
Pt has initial a1c of >7.5-tx?
lifestyle changes + dual therapy
-metformin + GLP, DPP4, Cromocriptine, AG
Pt has initial a1c of 7.5 or lower - tx?
lifestyle changes + monotherapy
What drug is contraindicated for pts w/ renal failure - DMII?
What is levothyroxine?
synthetic T4 so it can turn into T3
When should levothyroxine be taken?
What to be cautious about levothyroxine?
narrow therapeutic index so easy to make hyperthyroid or hypothyroid
How long does levothyroxine take to work?
ADR for aspart and lispro? Same as?
same as reg insulin and glargine
ADR for Repaglinide?
What antihyperglycemic has NO hypoglycemia?
ADR for metformin?
Who to avoid metformin in?
do not give to pts >80yo
vitamine B12 def
ADR for exentaide?
DI for exentaide?
ADR for acarbose?
flatulence and diarrhea
monitor LFT for liver toxicity
ADR for pioglitazone?
hepatoxicity -omnitor LFT
ADR for orlistat/
vitamin A D E K def