Flashcards in HemOnc Drugs Deck (14):
ADR of ASA?
Reye sx in kids
What is a type of antiplatelet?
How does clopidogrel work?
works well w/ASA
inhibits platelet activation
What is an anticoagulant? How to monitor?
What are anticoagulation agent?
direct factor Xa inhibitor - rivaroxaban
direct thrombin inhibitor - dabigatran
How to monitor unfractionated heparin? Reverse? ADR?
reverse w/ protamine
What is good about enoxaparin? Reverse?
-more selective = more predictable
-longer half life
reverse: partially w/ protamine
Which turn off factor Xa?
What is bad about rivaroxaban?
no antidotes to reverse
What is good about dabigatran?
no lab monitoring needed
What is dabigatran?
-direct thrombin inhibitor
What is 5-flurouracil? ADR?
fakes like a purine/pyrimidine by preventing DNA replication
ADR: cardiotoxic, alopecia, pancytopenia
What is methotrexate?
stops folic acid reductase