Endo Misc

Question 1

What is the primary screening test for Acromegaly/Gigantism?

Answer 1

Insulin Growth Like Factor will be increased

Question 2

What test confirms Acromegaly/Gigantism?

Answer 2

Oral glucose suppression test: Increased GH levels

Question 3

What medication causes gynecomastia?

Answer 3

Spironolactone

Question 4

DKA is MC seen in

Answer 4

T1DM

Question 5

HHS is MC seen in

Answer 5

T2DM

Question 6

What major metabolic imbalances are present in DKA?

Answer 6

acidemia

hyperketonemia

Hyperglycemia

Question 7

CPx of DKA

Answer 7

abdominal pain, vomiting, and fatigue

Fruity Breath

Question 8

Dx for DKA

Answer 8

Glucose >250

Ketonuria

Question 9

Dx for HHS

Answer 9

Glucose > 600

Increased Serum Osmolarity

Question 10

Critical 1st step of managing DKA/HHS

Answer 10

Isotonic 0.9% NS

once hypotension resolves, then:

0.45% NS

When glucose levels = 250, switch to D5 0.45 (1/2) NS

Question 11

Next steps of Mgmt for DKA/HHS

Answer 11

regular insulin & potassium

Question 12

abnormal findings on thyroid function tests that occur in the setting of a nonthyroidal illness

Answer 12

Euthyroid Sick Syndrome

Question 13

Dx for Euthyroid Sick Syndrome

Answer 13

Decreased T4/T3 + Decreased TSH

Question 14

Triad of Grave’s Disease

Answer 14

1. diffuse goiter
2. exophthalmos
3. pretibial myxedema

Question 15

TSB receptor antibodies

Answer 15

Graves Disease

Question 16

RAIU scan will show _______ uptake in Grave’s Disease

Answer 16

RAIU scan will show increased diffuse uptake in Grave’s Disease

Question 17

MC therapy used for Grave’s Disease

Answer 17

Radioactive Iodine: destroys thyroid gland

Question 18

Tx for Grave’s Disease

Answer 18

Methimazole or PTU

BB for symptomatic relief

Question 19

Plummers Disease

Answer 19

toxic multinodular goiter

Question 20

CPx for toxic multinodular goiter/Toxic Adenoma

Answer 20

Both TMG & TA:

• diffuse enlarged thyroid
• NO skin/eye changes

Compressive sxs: dyspnea, dysphagia, stridor, hoarseness

Question 21

RAIU scan shows ___________ for TMG

Answer 21

RAIU scan shows patchy areas of both increased and decreased uptake for TMG

Question 22

RAIU scan shows ___________ for TA

Answer 22

RAIU scan shows Increased local uptake (hot nodule) for TMG

Question 23

Tx for TMG & TA

Answer 23

same as Graves

Question 24

What DM meds cause hypoglycemia?

Answer 24

Sulfonylureas: Glyburide, Glipizide

Meglitinides: “glinides”

All Insulin

Question 25

**fatal complication of untreated thyrotoxicosis after a precipitating event**

Answer 25

**Thyroid Storm**

Question 26

CPx of Thyroid Storm

Answer 26

**hypermetabolic state: palpitations, tachy, a-fib, high fever, N/V, psychosis, tremors**

Question 27

Labs in Thyroid Storm

Answer 27

Same as Graves

Question 28

Tx for thyroid storm

Answer 28

Traditionally: **BB** **Dexamethasone (impairs hormone production)** **PTU** **Potassium Iodide** \*\*Do not give **PTU or iodide** if exogenous overdose of levothyroxine\*\*