Endo Misc Flashcards
What is the primary screening test for Acromegaly/Gigantism?
Insulin Growth Like Factor will be increased
What test confirms Acromegaly/Gigantism?
Oral glucose suppression test: Increased GH levels
What medication causes gynecomastia?
Spironolactone
DKA is MC seen in
T1DM
HHS is MC seen in
T2DM
What major metabolic imbalances are present in DKA?
acidemia
hyperketonemia
Hyperglycemia
CPx of DKA
abdominal pain, vomiting, and fatigue
Fruity Breath
Dx for DKA
Glucose >250
Ketonuria
Dx for HHS
Glucose > 600
Increased Serum Osmolarity
Critical 1st step of managing DKA/HHS
Isotonic 0.9% NS
once hypotension resolves, then:
0.45% NS
When glucose levels = 250, switch to D5 0.45 (1/2) NS
Next steps of Mgmt for DKA/HHS
regular insulin & potassium
abnormal findings on thyroid function tests that occur in the setting of a nonthyroidal illness
Euthyroid Sick Syndrome
Dx for Euthyroid Sick Syndrome
Decreased T4/T3 + Decreased TSH
Triad of Grave’s Disease
- diffuse goiter
- exophthalmos
- pretibial myxedema
TSB receptor antibodies
Graves Disease
RAIU scan will show _______ uptake in Grave’s Disease
RAIU scan will show increased diffuse uptake in Grave’s Disease
MC therapy used for Grave’s Disease
Radioactive Iodine: destroys thyroid gland
Tx for Grave’s Disease
Methimazole or PTU
BB for symptomatic relief
Plummers Disease
toxic multinodular goiter
CPx for toxic multinodular goiter/Toxic Adenoma
Both TMG & TA:
- diffuse enlarged thyroid
- NO skin/eye changes
Compressive sxs: dyspnea, dysphagia, stridor, hoarseness
RAIU scan shows ___________ for TMG
RAIU scan shows patchy areas of both increased and decreased uptake for TMG
RAIU scan shows ___________ for TA
RAIU scan shows Increased local uptake (hot nodule) for TMG
Tx for TMG & TA
same as Graves
What DM meds cause hypoglycemia?
Sulfonylureas: Glyburide, Glipizide
Meglitinides: “glinides”
All Insulin