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GK PANCE > SIADH, DI > Flashcards

SIADH, DI Flashcards

1
Q

Persistent ADH release independent of serum osmolality

A

SIADH

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2
Q

Main causes of SIADH

A

SAH, small cell lung cancer

Meds: SSRIs, HCTZ

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3
Q

Increased oral water intake makes patient symptomatic

A

SIADH

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4
Q

Dx for SIADH

A

Urine Osmolality > 100 (concentrated urine)

Urinary Na+ ≥ 20

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5
Q

Serum Na+, Serum Osm and Urine Osm in SIADH

A

Serum Na+ decreased

Serum Osmolality Decreased

Urine Osmolality Increased

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6
Q

Tx for SIADH

A

Fluid restriction

+/- Demeclocycline

IV Hypertonic Saline w/furosemuide if severe hyponatremia or intracranial bleed

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7
Q

Serum Na+ and Serum Osmolality relationship

A

Both either inc or dec

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8
Q

What is osmolality

A

particles/water

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9
Q

Decreased ADH production

A

DI

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10
Q

MC type of DI

A

Central

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11
Q

Caused by lithium

Kidney does not respond to ADH

A

Nephrogenic DI

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12
Q

S/S of DI

A

Polyuria

Polydipsia

Nocturia

Hypernatremia

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13
Q

Dx for DI

A

Hypernatremia (Increased Serum Osm)

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14
Q

What establishes the Dx for DI?

A

Fluid Deprivation Test: Decreased Uosm < 200, decreased specific gravity

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15
Q

What test differentiates Central vs Nephrogenic ADH

A

ADH stimulation test

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16
Q

Results of ADH stimulation test for Central DI

A

Decreased Urine Output

17
Q

Results of ADH stimulation test for Nephrogenic DI

A

No response

18
Q

Tx for central DI

A

DDVAP

19
Q

Tx for nephrogenic DI

A

Na+ & protein restriction

HCTZ

20
Q
A

GK PANCE (26 decks)

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