Endocine System Flashcards

1
Q

signaling molecules move between adjacent cells via membrane pores.

A

direct cell-to-cell communication

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2
Q

nervous system, very localized, quick, short term

A

synaptic cell-to-cell communication

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3
Q

cell communicates wit itself

e.g. cancer

A

autocrine cell-to-cell communication

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4
Q

cell communicates with neighboring cells through ISF

A

paracrine cell-to-cell communication

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5
Q

autocrine signal travels through?

A

interstitial fluid (ISF)

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6
Q

paracrine signal travels through?

A

interstitial fluid (ISF)

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7
Q

endocrine signal travels through?

A

blood

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8
Q

autocrine target?

A

same cell

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9
Q

paracrine target?

A

neighboring cell

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10
Q

endocrine target?

A

cells w/ receptors for that hormone anywhere in body

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11
Q

autocrine range of action?

A

local

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12
Q

paracrine range of action?

A

local

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13
Q

endocrine range of action?

A

systemic

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14
Q

releases hormones into blood

A

secreting cells

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15
Q

binds to receptor on target cell

A

hormone

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16
Q

neuron&raquo_space;> axon&raquo_space;> target cell

A

neural communication

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17
Q

cell&raquo_space;> hormone&raquo_space;> blood&raquo_space;> hormone&raquo_space;> target cell

A

endocrine communication

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18
Q

cell&raquo_space;> hormone&raquo_space;> ISF&raquo_space;> cell

A

autocrine communication

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19
Q

cell&raquo_space;> hormone&raquo_space;> ISF&raquo_space;> target cell

A

paracrine communication

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20
Q

external secretions, extracellular effects, secretions via ducts

A

exocrine glands

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21
Q

no ducts, capillaries for uptake of hormones into bloodstream, intracellular effects

A

endocrine glands

22
Q

nervous system form of communication?

A

electrical AND chemical

23
Q

nervous system response speed?

24
Q

nervous system adaption rate?

25
nervous system effects?
specific, 1 organ
26
endocrine system type of communication?
chemical only
27
endocrine system response speed?
slow
28
endocrine system adaption rate?
slow
29
endocrine system effects?
widespread, many organs
30
- too little hormone secretion - too much hormone secretion - unresponsive target - reaction to environmental hormone mimic
4 causes of endocrine disorders
31
- hypo secretion - hyper secretion - abnormal tissue response
causes of endocrine diseases
32
response of both hormones together= sum of their individual responses (1+1=2)
additive effect
33
hormones work together on target cell to produce an effect greater than the sum of their individual effects (1+1=3) e.g. FSH+testosetrone= increased sperm production
synergistic effects
34
1 hormone required for 2nd hormone to exert its full effect, target cell is primed by 1st hormone
permissive effects
35
1 hormone opposes action of other
antagonistic effect
36
insulin lowers blood glucose levels. insulin's antagonist, glucagon raises blood glucose levels. this is an example of what hormone interaction?
antagonistic effect
37
point-to-point messaging through nerves
nervous system
38
broadcasts its hormone messages to essentially all cells
endocrine system
39
Why don't all ALL cells in body respond to every hormone in the bloodstream?
only target cells have receptors
40
- unbound in blood - can't penetrate target cell - acts indirectly (via 2nd messenger) - faster amplification - lipid soluble
Hydrophilic hormones
41
- binds to transport protein in blood - penetrate plasma membrane, nuclear membrane - acts directly on genes of target cel - takes hrs/days to show effect - cant cross plasma membrane
Hydrophobic hormones
42
peptide/protein is hydro___?
hydrophillic
43
lipid derivatives are hydro___?
hydrophobic
44
estrogen, androgens, progestin
steroids from glands
45
mineralocorticoids, glucocorticoids, androgens
steroids from adrenal cortex
46
calcitriol
steroid from kidney
47
- released by endocrine cells near capillaries | - enters capillaries to travel to target organs
hormone release
48
lowers blood glucose levels
insulin
49
insulin's antagonist, raises glucose levels
glucagon
50
physiological stages in response to stress
general adaption syndrome
51
stage 1 in response to stress
-alarm - epinephrine is released -stored glycogen is consumed -