Endocrine Flashcards

(28 cards)

1
Q

modifiable RF in thyroid eye disease in Graves

A

smoking

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2
Q

thiazide electrolyte

A

hypercalcaemia

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3
Q

pheo test

A

24h collection urinary metanephrines

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4
Q

cushings test

A

resposne to high dose dex not low dose

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5
Q

prolactin high but hypogonadism and hypothyroidism

A

think stalk compression by non-functioning pituitary adenoma

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6
Q

DKA treated with insulin what can happen

A

hypokalaemia

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7
Q

what to give in initially if bad graves symptoms

A

propranolol for symptom relief

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8
Q

serum osmolality equation

A

2 x serum sodium + serum glucose + serum urea

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9
Q

low testosterone possible cause

A

pituitary adenoma eg prolactinoma caused low sex hormones

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10
Q

post-mi complication causing acute hypotension and pulmonary oedema with systolic murmur

A

papillary muscle rupture which causes acute mitral regurgitation

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11
Q

anterior pituitary hormone

A

flat pig
FSH, LH, ACTH, TSH, prolactin, intermediate MSH and GH

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12
Q

posterior pit hormones

A

ADH and oxytocin

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13
Q

sick day rules

A

sadman
SGLT2i, ACEi, diuretics, metformin, ARBs and NSAIDs

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14
Q

myxoedemic coma treatment

A

thyroxine and hydrocortisone

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15
Q

thyrotoxic storm treatment

A

beta blockers, propylthiouracil and hydrocortisone

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16
Q

when to add second diabetes drug

17
Q

metformin not tolerated due to side effects

A

1) try modified release
2) switch to second line therapy

18
Q

primary hyperparathyroidism

A

high PTH
high Ca
low phosphate

solitary adenoma or multifocal disease

19
Q

secondary hyperparathyroidism

A

high PTH
low or normal Ca
high phosphate
low vit D

low calcium causes parathyroid hyperplasia

20
Q

tertiary hyperparathyroidism

A

high or normal Ca
high PTH
low phosphate
high ALP

hyperplasia of the parathyroid glands after correction of underlying renal disorder

21
Q

osteomalacia bloods and symptoms

A

bone pain, tenderness and proximal myopathy
low ca, low phosphate and low vit D with high ALP and PTH

22
Q

management of primary hyperaldosteronism caused by bilateral adrenocortical hyperplasia

A

spironolactone

23
Q

causes and symptoms of primary hyperaldosteronism

A

hypertension and hypokalaemia
bilateral adrenal hyperplasia
adrenal adenoma

24
Q

C peptide in T1DM

25
Cushing's syndrome biochemical abnormality
hypokalaemic metabolic alkalosis
26
when is metformin contraindicated
eGFR <30 then metformin contraindicated so give another agent eg gliptin
27
what drug is linked to nec fash of the genitalia
SGLT2i
28
what do you need to do if patient presenting with polyuria and polydipsia and you think maybe DI
remember to do calcium levels before water deprivation to make sure there isn't hyperparathyroidism