Endocrine

Question 1

Where are glucocorticoids (cortisol) produced?

Answer 1

Zona fasciculata of adrenal cortex

Question 2

Were are mineralocorticoids (aldosterone) produced?

Answer 2

Zona glomerulosa of adrenal cortex

Question 3

What are the biochemical findings of an Addisonian crisis?

Answer 3

Hyperkalaemia
Hyponatraeia
Hypoglycaemia

Question 4

What is the medical treatment of a GH-secreting tumour?

Answer 4

Pegvisomant - GH receptor antagonist

Question 5

What is the medical treatment of a prolactinoma?

Answer 5

Cabergoline - dopamine receptor agonist

Question 6

What would cause a severe onset frontal headache?

Answer 6

Pituitary apoplexia - bleed into pituitary gland

Question 7

Does hypopituitarism cause hair gain or loss?

Answer 7

Loss

Question 8

Treatment of endometrial polyps?

Answer 8

Myomectomy

Question 9

Which hormone is used to treat fertility?

Answer 9

Progesterone

Question 10

What does LH do in makes?

Answer 10

Acts on Leydig cells to produce testosterone

Question 11

How is sperm produced?

Answer 11

Testosterone + FSH act on sertoli cells

Question 12

What are histological signs of papillary thyroid cancer?

Answer 12

Orphan annie nuclei

Psammoma bodies

Question 13

What would suggest Kallman’s syndrome?

Answer 13

Anosmia

GnRH deficiency