Endocrine Pancreas

Question 1

What does the Exocrine pancreas make?

Answer 1

• Lipase
• Amylase
• Trypsin (Digestion)

Question 2

What are the Endocrine pancreas cells called?

Answer 2

Pancreatic islets

Question 3

What doe the Endocrine pancreas produce?

Answer 3

• Glucagon & Insulin (glucose, lipid, and protein metabolism)
• Somatostatin

Question 4

What does glucagon do?

Answer 4

Increases blood glucose

Question 5

What does insulin do?

Answer 5

Decreases blood glucose

Question 6

What does somatostatin do?

Answer 6

Inhibits glucagon and insulin secretion

Question 7

What is the narrow range of blood glucose in dogs and cats?

Answer 7

Dogs: 3.3 - 6.7 mmol/L
Cats: 3.9 - 8.0 mmol/L

Question 8

When does diabetes mellitus occur?

Answer 8

Occurs when there is insufficient insulin secretion or when tissues do not respond to insulin

Question 9

What are some risk factors for DM in cats?

Answer 9

• Obesity
• Age
• Male (Neutered)
• Inactivity
• Amyloidosis
• Genetic predisposition in certain breeds (Burmese, Russian Blue, Norwegian Forest Cat, Abyssinian, Tonkinese)
• Acromegaly (excessive amounts of growth hormone is secreted)

Question 10

What are some risk factors of DM in dogs?

Answer 10

• Obesity
• Age
• Female
• Hyperadrenocorticism (Cushing’s Syndrome)
• Severe pancreatitis
• Pregnancy
• Genetic predisposition in certain breeds