Endocrine system regulation and exercise Flashcards
(31 cards)
Role of hypothalamus in endocrine system
synthesises and released tropic hormones
Act on anterior pituitary gland
Median eminence
axons in posterior pituitary go directly to capillaries
Role of posterior pituitary gland
secretion (no synthesis) of neuropeptides made by the hypothalamus
oxytocin
milk ejection reflex
fetus delivery: stretch receptors in cervix>hypothalamus>oxytocin>contraction of uterine smooth muscle
ADH/vasopresisn
regulation of water balance and osmolarity
constriction of smooth muscle around blood vessels to increase blood pressure
Peptide hormones synthesised and release by anterior pituitary
FSH
LH
growth hormone
TSH
prolactin
ACTH
FSH LH roles
target gonads to release sex hormones
growth hormone roles
target liver to secrete IGF-1
stimulates protein synthesis
postnatal growth
release is triggered by exercise and during sleep
TSH roles
target thyroid gland
role of prolactin
breast development and milk production
role of ACTH
targets adrenal cortex to secrete cortisol
trends in exercise and GH secretion
different types of exercise induce different GH responses
responses higher in younger individuals
effects of GH during exercise
stimulates gluconeogenesis in the liver
stimulates breakdown of triglycerides in adipose tissue
blocks glucose entry into tissues which increases fatty acid oxidation
endocrine response to stress
increasing release of cortisol from the adrenal cortex and epinephrine (adrenaline) from the adrenal medulla
Process of increased cortisol secretion
stimulus>inc CRH secretion from hypothamalus>inc anterior pituitary ACTH secretion>inc cortisol secretion from adrenal cortex
effects of increased cortisol
Permits action of epinephrine and norepinephrine on muscles and blood vessels.
Promotes glucose synthesis in the liver during long term fasting and exercise.
Increases lipolysis in the adipose tissue.
Maintains cellular concentrations of metabolic enzymes required to produce glucose and fatty acids between meals.
Decreases events associated with the inflammatory response such as capillary permeability and production
of prostaglandins.
When is cortisol secretion elevated
in the mornings
has a strong diurnal cycle
Is cortisol anabolic or catabolic?
catabolic
trend of cortisol with exercise
Elite endurance trained athletes have higher levels of cortisol
Fight or flight response
catecholamines>epinephrine and norepinephrine
effects of increased catecholamine secretion
Increased availability of energy (glucose and lipids) in the blood
Increased heart rate, breathing rate and cell metabolism.
Dilation of major blood vessels and constriction of peripheral capillary.
Pupil dilation.
what is the main catecholamine that is secreted by adrenal medulla
epinephrine
norepinephrine
precursor of epinephrine
mainly released by adrenergic neurones of SNS
receptor types that catecholamines bind to
alpha and beta adrenergic receptors