Endocrine system regulation and exercise Flashcards

(31 cards)

1
Q

Role of hypothalamus in endocrine system

A

synthesises and released tropic hormones
Act on anterior pituitary gland

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2
Q

Median eminence

A

axons in posterior pituitary go directly to capillaries

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3
Q

Role of posterior pituitary gland

A

secretion (no synthesis) of neuropeptides made by the hypothalamus

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4
Q

oxytocin

A

milk ejection reflex
fetus delivery: stretch receptors in cervix>hypothalamus>oxytocin>contraction of uterine smooth muscle

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5
Q

ADH/vasopresisn

A

regulation of water balance and osmolarity
constriction of smooth muscle around blood vessels to increase blood pressure

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6
Q

Peptide hormones synthesised and release by anterior pituitary

A

FSH
LH
growth hormone
TSH
prolactin
ACTH

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7
Q

FSH LH roles

A

target gonads to release sex hormones

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8
Q

growth hormone roles

A

target liver to secrete IGF-1
stimulates protein synthesis
postnatal growth
release is triggered by exercise and during sleep

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9
Q

TSH roles

A

target thyroid gland

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10
Q

role of prolactin

A

breast development and milk production

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11
Q

role of ACTH

A

targets adrenal cortex to secrete cortisol

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12
Q

trends in exercise and GH secretion

A

different types of exercise induce different GH responses
responses higher in younger individuals

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13
Q

effects of GH during exercise

A

stimulates gluconeogenesis in the liver
stimulates breakdown of triglycerides in adipose tissue
blocks glucose entry into tissues which increases fatty acid oxidation

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14
Q

endocrine response to stress

A

increasing release of cortisol from the adrenal cortex and epinephrine (adrenaline) from the adrenal medulla

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15
Q

Process of increased cortisol secretion

A

stimulus>inc CRH secretion from hypothamalus>inc anterior pituitary ACTH secretion>inc cortisol secretion from adrenal cortex

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16
Q

effects of increased cortisol

A

Permits action of epinephrine and norepinephrine on muscles and blood vessels.
Promotes glucose synthesis in the liver during long term fasting and exercise.
Increases lipolysis in the adipose tissue.
Maintains cellular concentrations of metabolic enzymes required to produce glucose and fatty acids between meals.
Decreases events associated with the inflammatory response such as capillary permeability and production
of prostaglandins.

17
Q

When is cortisol secretion elevated

A

in the mornings
has a strong diurnal cycle

18
Q

Is cortisol anabolic or catabolic?

19
Q

trend of cortisol with exercise

A

Elite endurance trained athletes have higher levels of cortisol

20
Q

Fight or flight response

A

catecholamines>epinephrine and norepinephrine

21
Q

effects of increased catecholamine secretion

A

Increased availability of energy (glucose and lipids) in the blood
Increased heart rate, breathing rate and cell metabolism.
Dilation of major blood vessels and constriction of peripheral capillary.
Pupil dilation.

22
Q

what is the main catecholamine that is secreted by adrenal medulla

23
Q

norepinephrine

A

precursor of epinephrine
mainly released by adrenergic neurones of SNS

24
Q

receptor types that catecholamines bind to

A

alpha and beta adrenergic receptors

25
effects of epinephrine
increased heart rate and blood pressure increased peripheral vasoconstriction increased lipid breakdown increased coronary and bronchial dilation increased conversion of glycogen to glucose
26
effects of norepinephrine
increased heart rate and blood pressure increased peripheral vasoconstriction
27
trend of epinephrine secretion and exercise
higher intensities and shorter periods of exercise trigger a greater release of epinephrine
28
exocrine and endocrine functions of the pancreas
exocrine> secretion of pancreatic enzymes for food digestion in the duodenum endocrine>secretion of insulin and glucagon
29
functions of insulin
lipogenesis and glycogenesis increases glucose uptake and storage in the liver as glycogen increases amino acid uptake and protein synthesis decreases lipolysis in adipose tissue
30
glucagon functions
promotes glycogenolysis in the liver stimulates gluconeogenesis in the liver
31
exercise and glucose regulation
glucagon secretion increases during exercise to promote glycogenolysis Epinephrine and Norepinephrine release further increase glycogenolysis. Cortisol levels also increase to promote protein catabolism for later gluconeogenesis. Growth hormone levels increase to increase fatty acid oxidation, lipolysis and gluconeogenesis. Insulin secretion deceases to lower the storage of glucose