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MRCP Part 2 > Endocrinology > Flashcards

Endocrinology Flashcards

(87 cards)

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1
Q

Cystic Fibrosis patient with weight loss and Diabetes Management

A

High Carbohydrate Diet + Basal Bolus Insulin

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2
Q

Initial Management of Hyperosmolar non-ketotic diabetic
coma

A

IV saline (0.9%) + IV insulin and subcutaneous
heparin.

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3
Q

Clinical Features of Adrenal Insufficency

A

Hyponatremia
Hyperkalemia (Upper Limit of Normal)
Hypotension

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4
Q

Reason for Erectile Dysfunction in DM patient with postural hypotension

A

Autonomic Dysfunction

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5
Q

GI Condition Associated with Increased Risk of Thyroid Cancer

A

Familial adenomatous polyposis

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6
Q

What is osmolar gap

A

The difference between measured serum osmolality and calculated serum osmolality

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7
Q

Diagnosis of SIADH

A

Euvolemic Hyponatremia with Normal Osmolar Gap Hypo osmolarity

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8
Q

Diagnosis of Beer Potomania

A

Hyponatremia with High Osmolar Gap

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9
Q

Management of Obesity in Type 2 DM with High HbA1c

A

Liraglutide 3 mg

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10
Q

Sick Euthyroid Disease

A

Low T3 and T4
Normal or Low TSH

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11
Q

Initial Management of Erectile dysfunction in Diabetes mellitus

A

Sildenafil

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12
Q

MODY Initial Management

A

Gliclazide

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13
Q

Kallmann Syndrome Clinical Features

A

Anosmia
Cleft Palate

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14
Q

Management of Kallmann Syndrome

A

Pulsed GnRH Therapy

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15
Q

Equation for Calculating Osmolarity

A

2(Na + K) + Urea + Glucose

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16
Q

Osmolarity in HHS

A

Plasma Osmolarity >320

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17
Q

Polyglandular syndrome Type 1

A

Adrenal Insufficiency
Hypoparathyroidism
Mucocutaneous Candidiasis

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18
Q

Polyglandular syndrome Type 2

A

Adrenal Insufficiency
Hypothyroidism
Type 1 Diabetes Mellitus

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19
Q

Polyglandular syndrome Type 3

A

Autoimmune Thyroiditis

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20
Q

Management of Venous Ulcers

A

Multi-Layer Compression Bandage

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21
Q

Initial Management of Turners Syndrome

A

Combined Estrogen-Progesterone Therapy

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22
Q

Pentagastrin stimulation test

A

Used for detection of Medullary Thyroid Cancer - MEN 2a

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23
Q

Most common hormone deficiency in Traumatic Brain Injury

A

Growth Hormone

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24
Q

Early Pregnancy Hyperthyroidism Management

A

Proplythiouracil

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25
Late Pregnancy Hyperthyroidism Management
Carbimazole
26
Conditions causing Necrobiosis lipoidica diabeticorum
- Type 1 Diabetes Mellitus - Rheumatoid Arthritis
27
Ulcerated Yellow-Brown Lesion which seen in legs of Type 1 Diabetes Patient
Necrobiosis lipoidica diabeticorum
28
Tumor Associated with Necrolytic migratory erythema
Glucaganoma
29
Necrobiosis lipoidica diabeticorum Management
Topical Steroids
30
Low LH and FSH along with Tall Individual with absent Sex development
Kallman Syndrome
31
Increased LH and FSH but Tall + Delayed Puberty + Small testis +
Klinefelter Syndrome
32
Large Testis + Learning Difficulty
Fragile-X Syndrome
33
RET oncogene +ve in
MEN 2
34
Medication better than OCP in PCOD for acne and hirsutism
Co-cyprindiol
35
Hyperthyroidism Next Investigation
Thyroglobulin If Low -> Factitious thyrotoxicosis If High -> thyroid carcinomas
36
Hashimoto's thyroiditis antibodies
Anti-thyroglobulin antibodies Anti-Thyroid Peroxidase Antibody
37
Graves Disease Antibodies
TSH Receptor Antibody
38
Renal Artery Stenosis Lab Finding
Hyperenemic Hyperaldosteronism and Hypokalemia
39
Somatostatinoma Triad
Diabetes Mellitus Gallstones Diarrhoea
40
Turners Syndrome most common complication
Osteoporosis
41
Hormone Replacement Therapy GI advantange
Decreases Risk of Ca Colon
42
Management of Isolated Elevated T3 levels
Carbimazole
43
How to differentiate cushings and pseudo cushings
Pseudo cushings have diurnal decrease of Plasma Cortisol of >50% NO change in Cushings disease
44
Long term complication of acromegaly
Left Ventricular Hypertrophy
45
Thiazide Abuse findings
- Normal BP - Hypokalemia - High Bicarbonate
46
NICE recommendation for Cinacalcet
Only for the management of patients with hyperparathyroidism who are on dialysis and not fit for surgery
47
Micro-Adenoma of Pituitary management in Non pregnant Individual
Cabergoline
48
Micro-Adenoma of Pituitary management in Pregnant Individual or plan to start a family
Bromocriptine
49
Prolactin levels to consider Macro-Prolactinoma
5000 or more
50
Management of Venous Ulcers with ABPI of > 0.81
Compression Bandage
51
Elevated Insulin + Low or Normal C-Peptide
Insulin Abuse
52
Elevated Insulin + Elevated C-Peptide
Insulinoma Suphonylurea Abuse
53
Hypercalcemia + Hypermagnesemia + Hypocalciuria
Familial Hypocalciuric Hypercalcemia
54
Diabetes Patient on Insulin complaints of Hypoglycemia during exercise episodes
Change to Basal Bolus Regimen
55
Management of Diabetes associated with Pancreatitis
INSULIN Only
56
Lab Findings of Thyroxine-binding globulin deficiency
Normal TSH Low Total T4 Normal Free T4
57
Asymptomatic Primary Hypoerparathyroidism Surgery Indication
1. Creatinine Clearance <30% or more 2. >10 mmol/24 hrs urine calcium excretion
58
Follow up for Microprolactinoma
Yearly MRI
59
Inital management of Graves Ophthalmopathy
IV Glucocorticosteroids
60
Hypokalemia not getting corrected despite IV KCl
Correct Hypomagnesemia
61
Management of Severe Proliferative Diabetic Retinopathy
Pan-Retinal Photocoagulation
62
Features of Addisons Disease
Low 9 am Cortisol and Increased ACTH levels
63
Weight Gain Proximal Myopathy Increased CK
Hypothyroidism
64
Lithium patients with Hypernatremia
Nephrogenic DI
65
Most common causative organism for UTI in Type 2 DM
Extended Spectrum Beta Lactamase E.Coli
66
Management of Hypertension in Cushings Prior to surgery
Ketoconazole 600-800 mg
67
Addisons Disease Physical examination Finding
Significant Postural Hypotension
68
Diabetic Peripheral neuropathy Medications
Duloxetine Gabapentin Amityptalline
69
Hypertrygleceridemia alone management
Fenofibrates
70
Very high platelet count along with High Potassium
Pseudohyperkalemia due to essential thrombocytosis
71
Shortening of 4th finger of both hands
Pseudohypoparathyroidism
72
Initial management of Pseudohypoparathyroidism
Calcium and Vitamin D Supplementation
73
Inital management of DeQuervains Thyroiditis
Ibuprofen - NSAID
74
Uncommon cause of elevated prolactin levels
Chronic Kidney Disease Hypothyroidism Verapamil Metaclopromide
75
Post Partum Thyroiditis Antibodies
Anti-Microsomal Antibody +ve Anti TPO +ve
76
CT shows Presence of Supracellar calcified cyst with cyst containing CSF Diagnosis
Craniopharyngioma
77
Management of Charcots Joint
Below Knee Cast or Immobilization
78
Joint Swelling and Chronic Joint pain with Poorly controlled Type 2 DM
Charcots Joint
79
Management of Patient on Gliclazide with Hypoglycemia
Change to Sitagliptin
79
Initial management of Type 1 Diabetes Mellitus with unpredictable hypoglycemic episodes
Dose Adjustment for Normal Eating (DAFNE) Education
80
How to confirm diagnosis of Primary Polydipsia
Urine Osmolality >800 mOsm with water deprivation only
80
History of Multiple Fractures + Precocious Puberty + Cafe Au Lait Spots
McCune-Albright Syndrome
81
Achondroplasia gene affected
Fibroblast growth factor receptor 3 (FGFR3)
81
DKA Patient management other than Insulin and IV Fluids
S/C Heparin (Prone to Thrombus formation)
82
83
IOC for Klienfilters Syndrome
Elevated LH and FSH
84
IOC for Kallmann Syndrome
Low GnRH

MRCP Part 2 (12 decks)

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