Endodontic Infection

Question 1

summarise the immune response in endodontic infections

Answer 1

macrophages attracted due to LPS and cytokines which migrate to apex
present antigens to adaptive immune cells such as T cells and B cells

Question 2

what are the key bacteria in endodontic infections

Answer 2

enterococcus faecalis
porphyromonas endodontalis

Question 3

what type of bacteria is enterococcus faecalis

Answer 3

anaerobic gram positive rods

Question 4

is a primary or secondary endodontic infection more likely to contain e faecalis and why

Answer 4

secondary
predominantly gram positive microorganisms whereas primary endo infections are more gram negative

Question 5

what are the virulence factors of e faecalis

Answer 5

endotoxins
adhesins
collagenases
hyaluronidase
immune evasion

Question 6

what are the management considerations for endodontic infections

Answer 6

sodium hypochlorite and EDTA
either mechanically manage via RCT or you can remove the root

Question 7

what is the best way to treat a mono species infection

Answer 7

sodium hypochlorite and EDTA together

Question 8

what is the impact of yeast of endo infections

Answer 8

it supports bacterial growth and propels bacteria down the dentine tubules