What lines the auditory meatus and external canal?
(containing sebaceous and ceruminous glands)
What lines the middle ear?
Columnar lined epithelium
Which type of epithelium lines the nasal vestibule?
Which type of epithelium lines the nose and sinus?
(pseudostratified ciliated columnar, seromucinous glands)
It is also called Schneiderian epithelium
Which two components comprise a salivary gland?
Why are peripheral myoepithelial cells useful in salivary glands?
They have contractile properties
What is otitis media?
Inflammation of the inner ear
What can cause otitis media?
Viral infections mostly
Chronic otitis media may be as a result of which bacteria?
What is cholesteatoma?
Keratinised squamous epithelium in middle ear
(it is NOT a tumour)
Which age group is affected by cholesteatoma?
Despite not being a tumour, which neoplastic property does cholesteatoma possess?
High cell turnover
What is the pathogenesis for cholesteatoma?
Chronic otitis media
Perforation of tympanic membrane
Which tumour is associated with the vestibular portion of the vestibulocochlear nerve?
In which bone do vestibular schwannomas associate?
What is the classic microscopic appearance of a schwannoma?
How do most vestibular scwannoma cases present?
Sporadic and unilateral
If a vestibular scwannoma presents bilaterally in a young patient, what should be suspected?
Neurofibromatosis Type 2
Which type of neurofibromatosis is more common?
For which reasons may an individual develop neurofibromatosis type 2?
- AD inheritance
- Sporadic mutation in NF2 gene
Which clinical features will be seen in a patient with neurofibromatosis type 2?
- Multiple meningiomas
- Bilateral vestibular schwannomas
- Posterior subcapsular cataracts
- Pigmentary retinopathy
Which common benign swelling is often found in the nasal cavity?
What can induce nasal polyps?
- Aspirin sensitivity
- Cystic fibrosis (young)
What must be ruled out if a child presents with nasal polyps?
What are the identifying features of nasal polyps microscopically?
How may a patient with GPA present?
- Pulmonary or renal disease
- Symptoms of nasal congestion
How is GPA identified?
What is the most common cause of septal ulceration?
(GPA can also cause)
What are the identifying features of GPA on microscopy?
- Liquefactive or coagulative necrosis
- Profuse eosinophils and multinucleated giant cells
- Pallisading histiocytes and giant cells with central necrosis
- Few lymphocytes and plasma cells
Which benign tumours may be found in the nasal cavity?