Enteric Viruses Flashcards
(16 cards)
Norovirus
(+)ssRNA, icosahedral, nonenveloped
Calicivirus
Norovirus symptoms
Vomiting, diarrhea
Most common cause of acute gastroenteritis, foodborne disease outbreaks in the U.S.
Rotavirus
dsRNA, icosahedral, nonenveloepd
Reovirus
Rotavirus structure
Remarkably stable triple-layered particle (TLP)
Rotavirus pathogenesis
DLP component NSP4 enterotoxin: promotes diarrhea
Rotavirus symptoms
Vomiting and fever for 2-3 days, profuse watery diarrhea for 4-5 days
Poliovirus
(+)ssRNA, icosahedral, nonenveloped
Picornavirus
Poliovirus transmission
Fecal-oral transmission
Where does poliovirus replication occur?
GI tract
What do enteroviruses cause?
Variety of clinical syndromes besides gastroenteritis, acute flaccid myelitis
What does astrovirus (HAstV) cause?
Diarrhea, nausea, vomiting
Hepatitis A Virus
(+)ssRNA, icosahedral, nonenveloped
Picornavirus
Hepatitis A symptoms
Jaundice
Hepatitis E virus
(+)ssRNA, icosahedral, nonenveloped
In which group of people is Hepatitis E virus mortality 20%?
Pregnant women (especially high in the third trimester)
Hepatitis E transmission
Fecal-oral transmission
