Respiratory Viruses

Question 1

Coronavirus

Answer 1

(+)ssRNA, helical, enveloped

Question 2

Influenza

Answer 2

(-)ssRNA, helical, enveloped

Orthomyxovirus

Question 3

Influenza surface markers

Answer 3

HA - viral receptor binding protein and fusion protein

NA - cleavage of host cell sialic acids

Question 4

Human Rhinovirus (HRV)

Answer 4

(+)ssRNA, icosahedral, nonenveloped

Picornavirus

Question 5

Human Parainfluenza Virus (HPIV)

Answer 5

(-)ssRNA, helical, enveloped

Paramyxovirus

Question 6

Human Respiratory Syncytial Virus (HRSV)

Answer 6

(-)ssRNA, helical, enveloped

Paramyxovirus

Question 7

What does HRSV cause?

Answer 7

Lower respiratory tract illness in young children

Question 8

Human Metapneumovirus (HMPV)

Answer 8

(-)ssRNA

Pneumoviridae

Question 9

Human Adenovirus (HAdV)

Answer 9

Nonenveloped dsDNA

Question 10

What does HAdV cause?

Answer 10

Broad range of illnesses

Question 11

Human Parvovirus B19

Answer 11

Nonenveloped ssDNA

Question 12

Human Parvovirus B19 transmission

Answer 12

Respiratory droplet, maternal-fetal intrauterine

Question 13

Human Parvovirus B19 symptoms

Answer 13

5th disease in children (“slapped cheeks”), acute symmetric polyarthropathy, aplastic crisis, chronic anemia, hydrops fetalis (RBC maturation arrest -> cardiac failure)

Question 14

Measles Virus

Answer 14

(-)ssRNA, helical, enveloped

Paramyxovirus

Question 15

Measles symptoms

Answer 15

Causes fever with cough, coryza, conjunctivitis (3 C’s)
Koplik spots (grains of white sand on red background)
Rash

Question 16

Human Mumps Virus

Answer 16

(-)ssRNA, helical, enveloped

Paramyxovirus

Question 17

Mumps symptoms

Answer 17

Parotitis (painful swelling of the salivary glands), Orchitis
Meningitis or encephalitis (rare)

Question 18

Rubella

Answer 18

(+)ssRNA, icosahedral, enveloped

Togavirus

Question 19

Rubella symptoms

Answer 19

Rash, fever

Congenital rubella syndrome