Environmental and Tox Flashcards

1
Q

What is the formula to convert Celcius to Fahrenheit

A

(Cx1.8)+32=F

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2
Q

What Medication is contraindicated in cocaine overdose?

A

Beta-blocker

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3
Q

What ECG effects does Digoxin have

A

PR interval prolongation, ST depression or T wave inversion/biphasic T wave.
PR interval prolongation is significant and may indicate toxicity

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4
Q

Clinical manifestations of salicylate toxicity include

A

Respiratory rate increase, headache, vertigo, tinnitus, confusion, sweating and thirst.
Severe symptoms include agitation seizures and coma.

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5
Q

What enzymes are elevated in Heatstroke?

A

CPK,SGOT, SGPT and LDH

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6
Q

Under what temp is defibrillation not effective

A

30 C

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7
Q

What blood transfusion reaction can occur within minutes of administration?

A

Acute Hemolytic reaction
Rapid destruction of donor blood cells by host antibodies.

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8
Q

What is the treatment for acetaminophen poisoning?

A

N-acetylcysteine (NAC)

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9
Q

Antidote for Coumadin Overdose

A

Vit K

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10
Q

Antidote for Heparin toxicity

A

Protamine Sulfate

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11
Q

Lab Value associated with Coumadin and measures the extrinsic pathway.

A

PT

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12
Q

Lab Value associated with Heparin and measures the intrisic pathway.

A

PTT

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13
Q

Treatment of Dig toxicity

A

Digifab, Mag, phenytoin, lidocaine

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14
Q

What is the target urine output for Rhabodo patient’s

A

100ml/hr

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15
Q

Treatment for malignant hyperthermia

A

dantoline

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16
Q

At what temp does the ECG progress to sinus brady, PR prolongation, QT prolongation?

A

32C or 90F

17
Q

At what temp do Osborne waves present

18
Q

Define Histotoxic Hypoxia

A

Deficiency in the alveolar oxygen exhange.

19
Q

Define hypemic hypoxia

A

reduction in the oxygen carring capacity of the blood, anemia, hemorrhage

20
Q

Define stagnant hypoxia

A

reduced total CO, pooling of blood or restriction of blood flow.

21
Q

List Organophosphate toxicity medication treatments

A

Diazepam, atropine, Pralidoxime (2Pam)

22
Q

ARDS and DIC are a result of what in the hyperthermic patient?

A

Lysosomal enzymes,
The release of destructive lysosomal enzymes occurs as a result of extensive muscle damage.

23
Q

What is the antidote for toxic alcohol toxicity?

A

Fomepizole,
it prevents formation of toxic metabolites

24
Q

Digitalis toxicity is exacerbated by

A

Beta Blockers

25
S/S of ASA toxicity
GI ulcer, tinnitus
26
Antidote for Iron Poisoning
deferoxamine
27
what patient presents with possible seizures, elevated anion gap and nystagmus
Ethylene glycol ingestion Toxic alcohol ingestion
28
S/S of Iron ingestion that indicates treatment is effective
Urine that it pink in color
29
Organophosphate exposure causes the overproduction of the neurotransmitter acetylcholine by
Deactivation of the acetylcholinesterase enzyme which is responsible for the break down of acetylcholine
30
Which drug will require the addition of sodium thiosulfate in the infusion bag to prevent thiocyanate toxicity?
Nitroprusside
31
Define the temps for hypothermia
Mild 32-35C alert shivering Moderate 28-32C loss of shivering, lethargy, confusion Severe 28C bradycardia, hypotension, unconcious
32
What should be applied to hydrofluoric acid exposure?
Calcium gluconate gel.