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Critical Care > Pharm and Labs > Flashcards

Pharm and Labs Flashcards

1
Q

Succinylchoine

A

Anectine 1-2 mg/kg Depolarizing neuromuscular blocker
Targets the nicotinic acetylcholine receptors on the post synapse
can cause malignant hyperthermia, hyperkalmeia and increase intraoccular pressure
Causes Serum Potassium to rise about 1mmol/L

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2
Q

Dantroline

A

Dantrium 1mg/kg ever 4-6 hours for malignant hyperthermia

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3
Q

Rocuronium

A

Nondepolarizing neuromuscular block 1mg/kg

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4
Q

Vecuronium

A

Nondepolarizing neuromuscular block 0.1mg/kg

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5
Q

Why dont we given atropine to a heart transplant patient

A

the vagus nerve has been cut during the transplant

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6
Q

What should be give for wide complex dysthryhmia in presence of HyperKalemia and diphenhydramine, TCA, phenobarbital or cocaine toxicities

A

Sodium Bicarb 1mEq/kg

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7
Q

What other drug must be given to wide complex dysthythmia where hyperkalemia is suspected

A

Calcium chloride or gluconate 500-1,000mG IV slowly over 5-10 minutes

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8
Q

Sodium normal value

A

135-145

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9
Q

Potassium normal value

A

3.5-5

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10
Q

Chloride normal value

A

95-105

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11
Q

calcium normal value

A

8-10

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12
Q

BUN normal value

A

4-20

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13
Q

Creatinine normal value

A

0.6-1.2

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14
Q

Anion Gap normal value

A

12-20
increased gap indicated acidosis

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15
Q

Serum Os normal value

A

275-295

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16
Q

Lactate normal value

A

<2

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17
Q

Hemoglobin normal value

A

12-16 female
14-18 males

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18
Q

Hematocrit normal value

A

45-55%

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19
Q

WBC

A

4-11K

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20
Q

What does increased BNP mean

A

Heart Failure

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21
Q

What does increased BUN and Creatinine mean

A

Renal Failure/renal injury

22
Q

When is rhogam given? Why?

A

28 Weeks gestation for Rh negative pregant females.
after delivery
after any trauma/bleding

23
Q

What is given for postpartum hemorrhage?

24
Q

Medication given for eclampsia?

A

Magnesium Sulfate

25
Meds for preterm labor
Mag, trebuteline
26
Ketamine dose, class, action, SE and contraindications
Analgesia 0.1-0.3 mg/kg Dissociatoin 1-2 mg/kg Action- NMDA atagonist SE- hypersalavation, apnea
27
Etomadate dose, class, action, SE and contraindications
0.3mg/kg max of 40 mg Action- GABA agnoist SE-resp depression/apnea Contra- adrenal dependant patients, addisons disease
28
Propofol dose, class, action, SE and contraindications
10-100 mcg/kg/min Action- potent GABA agonist with sedative and anticonvulsant effects SE- hypotension Contra- egg allergy Note- Propofol infusion syndrome can occur with prolong infusion of propofol, associated with rhabdo, hyperK, renal failure
29
Lorazepam Midazolam Diazepam
Benzodiazepines, primary GABA agonist with sedation, anxiolytic and anti-convulsant properties Ativan- 1-2mg Versed 2-10 mg best IM option Diazepam 5-10mg IV not IM
30
Dexmedatomidine
Precedex Alpha 2 receptor agonist causing sedation, analgesia and anesthesia with out depressing resp drive SE watch for bradycardia
31
Morphine Fentanyl Hydromophone
Opioids Morphine 2-10 mg Fentanyl .5-1 mcg/kg, for the TBI pt 3mcg/kg Dilaudid 0.5-2mg Can cause resp depression,
32
Albuterol
Beta 2 adrenergic Agonist, bronchiole smooth muscle relaxer 2.5-5mg neb
33
Trebutaline
Breathine-beta 2 adrenergic agent, smooth muscle relaxer 0.25 mg SQ
34
Ipratropium
Atrovent- anticholinergic agent causing bronchodilation and dries mucosal secreations 0.5mg neb
35
Methylprednisolone Dexamethasone
Steroids, given to reduce swelling in the lower airways Solumedrol 125mg/ ped 1-2 mg/kg Decadron 5-20mg/ped 0.6mg/kg
36
Magnesium Sulfate
Smooth muscle relaxer, cns depressant and cardiac membrane stabilizer Bronchospasm/afib 2g in 100ml over 10 mintues Eclampsia/preterm labor 4 g in 100 ml over 20 minutes torsades 2-4 g SIVP Mag toxicity- Decreased mental status, hypotension, reducted deep tendion reflexes (reversal agent- calcium chloride)
37
Phenylephrine
Neosynephrine, vasopressor that causes pure alpha 1 agonist causing pure vasoconstriction 50-200mcg/min or 100 mcg push dose
38
Vasopression
ADH- vasopressor that targets V receptors causing potent vasoconstriction and reuptake of water 0.03 units/min
39
Nicardipine
Cardine, vasodilator that is a dihydropyridine calcium channel blocker and targets arterial smooth muscle. Blocking calcium from entering which reduces contraction, potent atrterial vasodilation. Mainly given during ischemic and hemorrhagic stroke and aortic disection 5-15 mg/hr
40
Nitroprusside
Nitropres- vasodilator that has a high affinity for arterioles given for hypertensive crisis and acute heart failure. need to monitor for cyanide toxicity.
41
Epinephrine
Adrenaline- Inopressor- catecholamine with equal inotropic and vasopressor properties Shock- 2-10 mcg/min PED dose 0.05mcg/kg/min Asthma/croup 1-4 mg nebulized Anaphylaxix 0.5 mg 1:1,000 IM PED dose 0.01 mg/kg of 1:1,000 IM
42
Norepinephrine
Levophed- Inopressor- catecholamine, Low dose caues venoconstriction, high doses cause arterial system 2-20 mcg/min
43
Dobutamine
Inodilator- synthetic catecholamine, pure beta 1 adrenergic agent- increase FRAC Cardiogenic shock and acute heart failure, increases CO by reducing SVR through arterial vasodilation while increasing FOC and HR 2-20 mcg/kg/min
44
Milrinone
Primacor- phosphodiesterase inhibitor- increases FOC and arterial vasodilation. Cardiogenic shock and acute heart failure- 0.375-0.75 mcg/kg/min
45
Mannitol
Hypertonic solution, 1g/kg IV
46
Flumazenil
Romazicon- GABA antagonist- 0.2 MG max of 1 mg Ped dose 0.01 mg/kg SE refractory seizures
47
2PAM
Acetylcholinersterase activator allows for the activation of the enzyme responsible for breakingdown acetylcholine, reversal agent for organophospate poisoning and weaponized nerve agents 1-2 grams
48
Physotigmine
Used for anticholinergic drug overdose (benadryl and atropine)
49
Hydroxocobalamin
Vit B12, reversal agent for cyanide toxicity
50
Sodium Thiosulfate
Reversal agent for cyanide toxicity
51
Pitocin
oxytocin- hormone produced in the hypothalmus and relased by the posterior pituitary gland Indicated for post partum hemorrhage and eliciting uterine contraction to reduce bleeding 10 units
52
What is the formula for anion gap?
(Na+K)-(Cl+HCO3)=Anion Gap

Critical Care (13 decks)

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