Environmental Emergencies & Toxicology Flashcards

(78 cards)

1
Q

Shivering stops at what temperature?

A

32*C

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2
Q

Body’s response to cold

A

Increased CBG
Respiratory acidosis
Enzyme function drops dramatically

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3
Q

Mild hypothermia temperature

A

32C - 34C

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4
Q

Moderate hypothermia temperature

A

29C - 32C

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5
Q

Severe hypothermia temperature

A

<28*C

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6
Q

S/S of Mild hypothermia

A

Increased basil metabolic rate
Increased cardiac output
Decreased heart rate at 32*C

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7
Q

S/S of Moderate hypothermia

A

LOC and SVR decrease
Acidosis
Decreased cardiac output
Hyperglycemia

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8
Q

S/S of Severe hypothermia

A

PT and APTT increase by 50%
Platelets decrease by 40%
Prolonged PR, QRS, QT
Osborne waves

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9
Q

V Fib risk is highest at ____.

A

22*C

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10
Q

Defer medications until core temp is ____.

A

> 30*C

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11
Q

Enzymatic retardation occurs at _____.

A

<33*C

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12
Q

Examples of passive external rewarming

A

Patient is allowed to rewarm self
Blankets
Heater in truck

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13
Q

Examples of active external rewarming

A

Heat placed on body surfaces mainly neck, groin, and axilla

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14
Q

Examples of active internal rewarming

A

Heat directly to core using warm IV fluids (warmed to 39*C), hemodialysis, gastric lavage, rectal lavage, ECMO

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15
Q

Sweat evaporation can lead to fluid loss of _____.

A

1-3 L/HR

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16
Q

High output failure may lead to ____.

A

AMI

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17
Q

Body’s response to heat

A
NA+ loss causing cerebral edema and seizures
Increased clotting times
ARDS/DIC
Hypokalemia
ATN
Rhabdomyolysis
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18
Q

Define heat cramps

A

Cramps of muscles in high heat caused by hyponatremia

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19
Q

Define heat exhaustion

A

Increase in core temperature without neurological impairment. Patient retains ability to sweat.

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20
Q

Define Heat stroke

A

Failure of body to dissipate heat effectively
Altered LOC
Core temp >42*C

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21
Q

Heat cramp treatment

A

Remove from heat, rehydrate with salt containing solution

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22
Q

Heat exhaustion treatment

A

remove from heat, cool patient, fluid replacement with electrolytes

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23
Q

Heat stroke treatment

A

Aggressive cooling and airway management
Iv fluids
Prevent shivering

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24
Q

Labs to monitor for heat emergencies

A

ABG for acidosis
Watch clotting factors for DIC
Monitor liver enzymes
Watch Sodium for hyponatremia

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25
Define Rhabdomyolysis
Myoglobin release clogging kidneys
26
Rhabdomyolysis treatment
Increase urine output to 2 ml/kg/hr Alkalinize urine with NaHCO3 Lasix/Mannitol
27
Hyponatremia treatment
Correct sodium with 3.3% saline SLOWLY | Central Pontine Myelinolysis
28
In heat emergencies, potassium levels are seen ___ due to renal wasting then ___ due to metabolic acidosis / Rhabdomyolysis.
Lower | Higher
29
Common Tricyclic Antidepressants
Tofranil, Elavil, Pamelor, Norpramin, Amitriptyline
30
TCA overdose
Blocks sodium channels Inhibits NorEpi reuptake Blocks Parasympathetic nervous system Torsade's, Widening QRS, tachycardia, VF, VT
31
TCA treatment
NaHCO3 (Ion trapping) NorEpi is first choice of pressor (Dialysis not helpful)
32
Two types of Beta-blocker overdoses (-lol drugs)
Type #1 - Cardioselective causes bradycardia with hypotension. Type #2 - Non-Cardioselective causes resp distress and exacerbates reactive airway disease
33
Treatment of beta-blocker overdose
Atropine Transcutaneous Pacing Glucagon 2-5mg IVP Dopamine for hypotension
34
Common calcium channel blockers
Verapamil, Cardizem, Nifedipine, Amlodipine, Nicardipine
35
Two types of calcium channel blocker overdoses
Type #1 - Cardiospecific causes severe bradycardia and AV dissociation Type #2 - Vasculomotor causing severe hypotension
36
Treatment of calcium channel blocker overdose
Calcium chloride/gluconate | Maintain insulin euglycemia
37
Common Digitalis agents
foxglove, oleander, digoxin, digitoxin
38
Digitalis toxicity
Visual disturbances of yellow/green halos | Bradycardia, SVT, VT, AV blocks
39
Treatment of Digitalis toxicity
``` Digoxin immunefab (Digibind) Lidocaine, Magnesium, Phenytoin for tachyarrhythmias ```
40
Define Hyperkalemia
K+ > 5.0 caused by profound acidosis (DKA, Vent management) or potassium supplements.
41
EKG changes with Hyperkalemia
Flattening / slurring of P waves with peaked T waves
42
Treatment of Hyperkalemia
``` Calcium Chloride NaHCO3 Insulin/D50 Lasix Kayexalate B2 agonist ```
43
Define Hypokalemia
K+ <3.5 caused by loop diuretic misuse, serum K+ and Ph levels important
44
Treatment of Hypokalemia
Potassium Chloride / Potassium Phosphorus Commonly 10-20 MEQ/HR Never more than 0.5-1.0 MEQ/KG/HR
45
Mild ASA poisioning
Tinnitus | Hyperventilation
46
Severe ASA poisoning
``` Seizures Electrolytes disturbances (TCO2, HCO3) ```
47
Treatment of ASA poisoning
Alkaline diuresis using HCO3 Hemodialysis Charcoal / gastric emptying
48
Stage 1 APAP Poisioning
30 min-24 hours "Flu like symptoms" | N/V, Malaise, Pallor, Diaphoresis
49
Stage 2 APAP Poisioning
24-48 hours "Owe my liver" Increased liver enzymes, serum bilirubin, PT RUQ pain / tenderness, oliguria from ATN
50
Stage 3 APAP Poisioning
48-72 hours "Gonna die now" | Jaundice, Hepatic encephalopathy, DIC, Death
51
Stage 4 APAP Poisioning
4 days - 2 weeks "I'm not dead yet" | Liver functions return to normal, asymptomatic, resolution period
52
Define APAP Poisioning
Ingestion of > 5G or 150 mg/kg. Measure serum levels after 4 hours.
53
APAP Poisioning treatment
N-Acetylcysteine (Mucomyst) | 70 mg/kg Q4 for 17 doses
54
S/S Ethylene glycol / Methanol Poisioning
Profound anion gap, osmolar gap, nystagmus, blindness, coma, myoclonic jerks. Look for fluorescent skin / clothes
55
Treatment of Ethylene glycol / Methanol Poisioning
IV Ethanol drip, Fomepizole (Antizol)
56
Cocaine Overdose
Benzos for anxiety | Avoid Beta blockers, use Alpha blockers for HTN
57
Benzo overdose
Flumazenil 0.1-0.2 mg IVP | Max 3-5 mg
58
Carbon Monoxide Antidote
O2 / Hyperbarics
59
Cyanide Antidote
Amyl / NA Nitrate, NA thiosulfate
60
Organophosphate Antidote
Atropine | 2-Pam
61
Methemoglobinemia Antidote
Methylene Blue
62
Anticholinergic Antidote
Physostigmine
63
Coumadin Antidote
Vitamin K, FFP
64
Heparin Antidote
Protamine Sulfate
65
Cerebral flow decreases 6-7% for every 1*C decline until __?
25*C
66
What are the symptoms of "after drop" in the hypothermic patient?
Cardiac dysrhythmias and hypotension.
67
What is "after drop" in a hypothermic patient?
Acidotic blood returning from extremities to core after rewarming
68
Mammalian diving reflex
Apnea Bradycardia Vasoconstriction
69
Define Acute Mountain Sickness
Occurs in non-acclimatized patients with recent travel to altitude within the last 24 hours. Usually occurs above 8000ft MSL
70
Acute mountain Sickness symptoms
Headache, N/V, weakness
71
Acute Mountain Sickness treatment
``` Descend 1000 to 3000ft Hydration Zofran Tyleno Dexamethasone ```
72
Define High Altitude Pulmonary Edema
Onset of symptoms occuring 2-4 days after rapid ascent >10,000 ft
73
High Altitude Pulmonary Edema symptoms
``` Rales Tachycardia Tachypnea Cough Dyspnea at rest ```
74
Treatment of High Altitude Pulmonary Edema
``` Descend Diamox Dexamethasone Nifedipine Oxygen Hyperbaric therapy ```
75
Define High Altitude Cerebral Edema (HACE)
Often at altitudes >12,000 ft MSL in climbers who ascend rapidly. Occurs after 5 days at sustained altitudes.
76
High Altitude Cerebral Edema symptoms
Visual changes Parasthesias (numbness) AMS Coma
77
Treatment of High Altitude Cerebral Edema (HACE)
``` Descend Diamox Dexamethasone Oxygen Hyperbaric therapy ```
78
Iron overdose Antidote
Deferoxamine | Pink urine "Vin rose urine" indicates therapeutic level