Enzymes and Regulation Flashcards

1
Q

Hexokinase - Inhibitor

A

G-6-P

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2
Q

Glucokinase - Activator

A

Glucose, Fructose-1-P, Insulin

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3
Q

Glucokinase - Inhibitor

A

Glucagon, Fructose-6-P

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4
Q

Pyruvate Kinase - Activator

A

Insulin, Fructose-1,6-BP

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5
Q

Pyruvate Kinase - Inhibitor

A

Alanine, ATP, Glucgon

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6
Q

PEP Carboxykinase - Activators

A

Cortisol, Glucagon, THroxine

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7
Q

Fructose-1,6,-Biphosphatase - Activator

A

Citrate, Cortisol

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8
Q

Fructose-1,6,-Biphosphatase - Inhibitor

A

High [AMP], Fructose-2,6-BP

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9
Q

G-6-Phosphatase - Activator

A

Cortisol

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10
Q

Pyruvate Kinase - Activators

A

Insulin, F-1,6-BP

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11
Q

Pyruvate Kinase - Inhibitors

A

Alanine, ATP, Glucagon

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12
Q

Pyruvate Carboxylase - Activators

A

Acteyl-CoA, Cortisol

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13
Q

Pyruvate Carboxylase - Inhibitiors

A

ADP

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14
Q

PEP Carboxykinase - Activator

A

Cortisol, Glucagon, Throxine

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15
Q

Fructose-1,6-Bisphosphatase - Activator

A

Citrate, Cortisol

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16
Q

Fructose-1,6-Bisphosphatase - Inhibor

A

High [AMP], F-2,6-BP

17
Q

ATP Synthase - Inhibitors

A

Oligiomyocin, Uncouplers (Thermogenin or DMP)

18
Q

Citrate Lyase - Activator

A

Glucose, Insulin

19
Q

Acetyl-CoA Carboxylase - Activator

A

Citrate

20
Q

Acetyl-CoA Carboxylase - Inhibitors

A

Glucagon, Epinephrine, high [AMP] Palmitate, PUFA

21
Q

Fatty Acid Synthase - Activator

A

Citrate

22
Q

Fatty Acid Synthase - Inhibitors

A

PUFA

23
Q

Carnitine Acyltransferase - Inhibitor

A

Manonyl-CoA

24
Q

Acyl-CoA Desaturase

A

Insulin (Creates Double Bond in FA)

25
Q

Acyl-CoA Desaturase

A

PUFA (Creates Double Bond in FA)

26
Q

DHFR - Inhibitor

A

Methotrexate

27
Q

Thymidyial Synthase - Inhibitor

A

Fluoracil

28
Q

Carbomyl Phosphate Synthase - Activator

A

PRPP

29
Q

Carbomyl Phosphate Synthase - Inhibitor

A

UMP, Purines

30
Q

Xanthine Oxidase - Inhibitor

A

Allopurinol - (helps with GOUT)