Epilepsy Flashcards

1
Q

How long does “tonic” last in tonic-clonic seizures

A

10-20 secs

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2
Q

How long does “tonic” last in tonic-clonic seizures

A

10-20 secs

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3
Q

How long does “clonic” last in tonic-clonic seizures

A

30 - 90 secs

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4
Q

What happens in “clonic” of Grand Mal seizures?

A

Everything loosens up. Stop seizing, lose bladder/bowel control. Chomping and foaming

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5
Q

3 stages of grand mal seizures?

A

Tonic, clonic, post ictal paresis (Todd’s paralysis)
Todd’s Paralysis is where parietal hemiparesis/weakness. It can affect speech and eye movements with no lasting changes and can last for hours)

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6
Q

What’s Todd’s paralysis?

A

Comes after Tonic-Clonic seizures. Get hemiparesis/weakness, Speech and eye movement issues with no lasting changes. May last hours

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7
Q

What’s status epilepticus

A

Seizure lasting > 30 mins. Can be on and off or straight. If on and off, no consciousness between.

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8
Q

When should you seek treatment for status epilepticus?

A

If >5mins
If 2 seizures with no consciousness betwee
Prevent brain damage!

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9
Q

How long does absence seizure last?

A

5 - 10 seconds

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10
Q

What’s the most common type of seizure

A

Focal seizure with impairment of consciousness

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11
Q

What’re the general seizures?

A
Tonic-Clonic
Status epilepticus
Absence
Tonic 
Clonic
Myoclonoic
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12
Q

Where are focal seizures usually and why?

A

Temporal lobe. Where amygdala is. Emotional changes

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13
Q

Where are sites of focal seizures without impairment of consciousness?

A

Occiptal - Aura

Motor - Jacksonian march

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14
Q

How long does a focal seizure with impairment of consciousness last?

A
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15
Q

Signs of focal seizure with impairment of consciousness?

A

Stare off into distance without responding to you. Might do automatisms (Smacking lips/chewing, snapping and repeating words)
Differentiate absence because lasts longer

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16
Q

Tests for seizures

A

EEG only funky when during seizure. Can’t rule out if normal
MRI unremarkable
Lab test for toxins and electrolytes

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17
Q

NT causes of seizure?

A

Increase Glutamate
Decrease in GABA
Na/K pump out of whack

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18
Q

Broad spectrum AEDs?

A

Valproate, Topamax, Lamotrigine

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19
Q

Absence AEDs?

A

Ethosuximide

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20
Q

Drug of choice for general seizures?

21
Q

Drug of choice for focal seizures?

A

Lamotrigine

22
Q

Side effects of AEDs?

A

Myopic shift and angle closure (Topamax only), N&V, rash, dyscrasia, decrease efficacy warfarin, birth control, antidepressants

23
Q

General epilepsy treatment plan?

A

AEDs
Surgically remove focal areas
Vagus nerve stimulation
Neuropace

24
Q

Prognosis?

A

Expected full lifespan

Kids 3-4x more likely to die though

25
What's SUDEp?
Sudden unexplained death in epilepsy. Death not related to epilepsy related injury
26
How long does "clonic" last in tonic-clonic seizures
30 - 90 secs
27
What happens in "clonic" of Grand Mal seizures?
Everything loosens up. Stop seizing, lose bladder/bowel control. Chomping and foaming
28
3 stages of grand mal seizures?
Tonic, clonic, post ictal paresis (Todd's paralysis) Todd's Paralysis is where parietal hemiparesis/weakness. It can affect speech and eye movements with no lasting changes and can last for hours)
29
What's Todd's paralysis?
Comes after Tonic-Clonic seizures. Get hemiparesis/weakness, Speech and eye movement issues with no lasting changes. May last hours
30
What's status epilepticus
Seizure lasting > 30 mins. Can be on and off or straight. If on and off, no consciousness between.
31
When should you seek treatment for status epilepticus?
If >5mins If 2 seizures with no consciousness betwee Prevent brain damage!
32
How long does absence seizure last?
5 - 10 seconds
33
What's the most common type of seizure
Focal seizure with impairment of consciousness
34
What're the general seizures?
``` Tonic-Clonic Status epilepticus Absence Tonic Clonic Myoclonoic ```
35
Where are focal seizures usually and why?
Temporal lobe. Where amygdala is. Emotional changes
36
Where are sites of focal seizures without impairment of consciousness?
Occiptal - Aura | Motor - Jacksonian march
37
How long does a focal seizure with impairment of consciousness last?
Less than 3 mins
38
Signs of focal seizure with impairment of consciousness?
Stare off into distance without responding to you. Might do automatisms (Smacking lips/chewing, snapping and repeating words) Differentiate absence because lasts longer
39
Tests for seizures
EEG only funky when during seizure. Can't rule out if normal MRI unremarkable Lab test for toxins and electrolytes
40
NT causes of seizure?
Increase Glutamate Decrease in GABA Na/K pump out of whack
41
Broad spectrum AEDs?
Valproate, Topamax, Lamotrigine
42
Absence AEDs?
Ethosuximide
43
Drug of choice for general seizures?
Valproate
44
Drug of choice for focal seizures?
Lamotrigine
45
Side effects of AEDs?
Myopic shift and angle closure (Topamax only), N&V, rash, dyscrasia, decrease efficacy warfarin, birth control, antidepressants
46
General epilepsy treatment plan?
AEDs Surgically remove focal areas Vagus nerve stimulation Neuropace
47
Prognosis?
Expected full lifespan | Kids 3-4x more likely to die though
48
What's SUDEp?
Sudden unexplained death in epilepsy. Death not related to epilepsy related injury