Epinephrine 1:10,000

Question 1

Epi 1:10,000 - Class

Answer 1

Natural Catecholamine (both alpha & beta effects)

Question 2

Epi 1:10,000 - Actions

Answer 2

• On the Bronchi (Beta 2) - Bronchodilation
• On the Peripheral Vasculature (Alpha) - Vasoconstriction
• On the heart (Beta 1) - increases HR, increases contractility, increases AV conduction, increases irritability

Question 3

Epi 1:10,000 - Indications

Answer 3

• Pulseless Dysrhythmias: Asystole/PEA/Pulseless VT & VF

* Anaphylaxis - for pt in anaphylaxis extremis (severe HoTN, severe respiratory distress)

Question 4

Epi 1:10,000 - Dosage/Route 1

Answer 4

Pulseless Dysrhythmias - Asystole/PEA/Pulseless VT & VF:

• 1 mg IVP/IO during CPR
• May repeat every 3-5 min durring arrest

Question 5

Epi 1:10,000 - Dosage/Route 2

Answer 5

Anaphylaxis:

• 0.1 - 0.3 mg slow IVP/IO
• May repeat every 5-15 min prn

Question 6

Epi 1:10,000 - Side Effects

Answer 6

• Supraventricular tachycardia (SVT)

* Ventricular irritability

Question 7

Epi 1:10,000 - Contraindications

Answer 7

None in the emergency setting

Question 8

Epi 1:10,000 - Special Information

Answer 8

• Assess pt and ECG for desired effect and side effects
• Alkalosis or acidosis may decrease effectiveness of epi
• Flush IV tubing between bicarbonate and epi

Question 9

Epi 1:10,000 - Pediatric Note

Answer 9

• Refer to Pediatric Drug Guide
• For pulseless arrest & Tx of symptomatic bradycardia unresponsive to O2 & ventilation:
• 0.01 mg/kg 1:10,000 (0.1 ml/kg) IV/IO q 3-5 min
• If no IV; 0.1 mg/kg Epi 1:1,000 via ET until IV/IO established
• For ET administration, dilute into 2-3 ml NS