Epithelium HY

Question 1

Where is simple squamous epithelium found?

Answer 1

Pericardium, Pleura, and Peritoneum

Question 2

Where is pseudostratified columnar epithelium found?

Answer 2

Trachea

Question 3

Where is non-keratinized stratified squamous found?

Answer 3

Esophagus, oral mucose, anal cavity, vagina, cervix

Question 4

What could a dysfunction in E-Cadherin lead to?

Answer 4

Malignant carcinoma & adenocarcinoma

Question 5

What are the components of desmosomes (macula adherens)?

Answer 5

Desmoplakins, plakoglobins, keratin, transmembranous proteins (desmocollins & desmogleins)

Question 6

What molecules found in gap junctions (zonula communicans)?

Answer 6

6 connexins; also found in cardiac and smooth muscle cells

Question 7

What are the components of the hemidesmosomes?

Answer 7

Integrein, perlecan, fibronectin, laminin, collagen type IV, VII, XVII

Question 8

What is the defect in Bullous Pemphigoid?

Answer 8

Auto-Ab against hemidesmosomes

Question 9

How is Basal Lamina visualized?

Answer 9

EM

Question 10

What is the role of Basal Lamina?

Answer 10

Serve as regeneration guide for epithelial, muscle, adipose, schwann cells using CAM and Integrins.

Question 11

How is Basement Membrane visualized?

Answer 11

PAS +ve

Question 12

What are components of the reticular lamina where the basement attaches?

Answer 12

Collagen Type I, III, and VII

Question 13

Microvilli characteristics?

Answer 13

Wheat field; ~1 um, LM: found in brush border of intestine; TEM: axial bundle>20 actin filaments; glycocalyx (furry coat)=PAS +ve

Question 14

Stereocilum characteristics?

Answer 14

Cactus; 8-15um; found male repro & inner ear epithelium

Question 15

Cilium characteristics?

Answer 15

7-10 um; axoneme of MT (9+1 axial doublets); found in endometrium, vas efferens, gametes, resp. epithelium; Primary cilium=immotile (sensory organs); Nodal cilium=motile (gastrulation)

Question 16

What is the defect and sx of Kartegener syndrome?

Answer 16

Defect in dynein arms therefore leading to defects in mucous movements & flagellum leading to chronic resp infections and infertility

Question 17

These glands lose their connections with surface epithelium from which they derived?

Answer 17

Endocrine glands

Question 18

These glands maintain their connections with surface?

Answer 18

Exocrine glands

Question 19

Tubuloacinar glands examples?

Answer 19

Pancreas exocrine, submandibular & sublingual salivary

Question 20

Tubuloalveolar glands examples?

Answer 20

Prostatic glands, mammary glands

Question 21

Simple tubular glands examples?

Answer 21

Intestinal glands

Question 22

Simple branched tubular glands examples?

Answer 22

Stomach glands

Question 23

Simple coild tubular glands examples?

Answer 23

Sweat glands

Question 24

Simple branched acinar glands examples?

Answer 24

Some urethral glands

Question 25

Compound tubular glands examples?

Answer 25

Duodenal glands

Question 26

Compound acinar glands examples?

Answer 26

Pancreas exocrine

Question 27

Comoound tubuloacinar glands examples?

Answer 27

Some salivary glands

Question 28

Sublingual salivary gland features?

Answer 28

Mucous acinus (protein)

Question 29

Parotid gland features?

Answer 29

Serous acinus

Question 30

Demilune secretion?

Answer 30

Mixed serous and mucous when demilunes are present