Equine Genetics Diseases Flashcards
(30 cards)
name one of the examples on the 5 panel test?
Glycogen branching enzyme deficiency
hereditary equine regional dermal asthenia
hyperkalemic periodic paralysis
malignant hyperthermia
polysaccharide storage myopathy
name the 6 or 7 panel tests?
myosin-heavy chain myopathy
overo lethal white syndrome
GBED is what type of disease?
autosomal recessive (2 copies to be affected)
symptoms of GBED?
abortions, stillbirths, weakness, hypothermia, sudden death
result of GBED?
fatal
HERDA is what type of disease?
autosomal recessive
what stallion does HERDA trace back to?
95% to Poco Bueno
symptoms of HERDA?
skin lesions, wrinkling of skin, hematomas, slow healing
result of HERDA
death, gets worse over time
name a famous stallion with a copy of HERDA?
metallic cat
what type if disease is HYPP?
autosomal dominant (1 or 2 copies to be affected)
HYPP traces back to who?
Impressive
symptoms of HYPP?
paralysis, weakness, muscle tremors
considerations and results of HYPP?
diet, exercise, not fatal if managed right
PSSM1 is what type of disease?
autosomal dominant
what horses commonly have PSSM1?
stock-type, drafts, TWH, morgans
symptoms of PSSM1?
muscle pain, weakness, sweating, hard to move
result of PSSM1?
okay if managed, high fat low starch diet
MH is what type of disease?
autosomal dominant
symptoms of MH?
hypermetabolic state, fever, sweating, breakdown of muscle tissue
triggers of MH?
hallithane anesthesia, stress
MYHM is a mutation in what gene?
MHY1
MYHM is what type of disease?
autosomal, only some show this with 2 copies
symptoms of MYHM?
tying up, muscle wasting, increase in serum creatine kinase
