ESR [038] Implantation, pregnancy and Lactation Flashcards

1
Q

Explain

A
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2
Q

Role of Progesterone in pregnancy ?

A

-Maintains the uterine endometrium

-Inhibits contractility of the uterine myometrium

  • Inhibits uterine production of prostaglandins (PGs promote parturition)
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3
Q

Role of Oestrogen in pregnancy ?

A

-Stimulate uterine blood flow

-Fetal development

-Onset of parturition

-Development of breast for lactation

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4
Q

What does each line represent ?

A
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5
Q

during pregnancy ; Progesterone is synthesised by ….

A

Progesterone is synthesised by the placenta alone

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6
Q

during pregnancy ; Estrogen is synthesised by ….

A

The conceptus (placenta and fetus together) can produce estrogens

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7
Q

The predominant estrogen in pregnancy ?

A

Oestriol

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8
Q

explain

A
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9
Q

Where does the Conjugation of steroids to sulphates happen ?

A

Occurs in fetal liver and adrenals

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10
Q

Results of Conjugation of steroids to sulphates ?

A

• Makes the steroids biologically inert

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11
Q

Function of Conjugation of steroids to sulphates in the fetal liver ?

A

-Sulphation of steroids protects the fetus from high levels of steroids necessary during pregnancy

• Makes the steroids biologically inert

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12
Q

Requirements of Parturition ?

A
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13
Q

hormones involved in Parturition ?

A

Oxytocin and Prostaglandin F2a

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14
Q

Effect of stimulation of the cervix on endocrinal secretions ?

A

Secretes Oxytocin

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15
Q

Role of Oxytocin in the process of Parturition ?

A

causes contraction of the myometrium

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16
Q

myometrial receptor changed that accur during Parturition ?

A

Oestrogen increases oxytocin receptors in myometrium

17
Q

Where is Prostaglandin F2a produced ?

A

in uterus

18
Q

Effect of Oxytocin and estrogen on Prostaglandin F2a production ?

A

Oxytocin and estrogen increase PG F2a production in uterus

19
Q

Effects of Prostaglandin F2a during Parturition ?

A

• Stimulates myometrial contractility

• Stimulates cervical softening

20
Q

explain

A
21
Q

the two key hormones for Breastfeeding ?

A
22
Q

explain

A
23
Q

Explain

A