1
Q

what is the endosymbiosis theory?

A

→endosymbiotic theory deals with the origins of mitochondria and chloroplasts

→Mitochondria and chloroplasts are believed to have developed from symbiotic bacteria.

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2
Q

what is some evidence for the endosymbiotic evolution of eukaryotic cells?

A

→mitochondria have their own circular genome which replicates independently of nuclear DNA
→ new mitochondria are produced by fission of existing mitochondria
→ all mitochondrial genomes share similarity with the Typhus bacterium “Rickettsia prowazekii”

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3
Q

what are plastids and where are they found?

A

→the plastid is a major double-membrane organelle found in the cells of plants, algae, and some other eukaryotic organisms.

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4
Q

what are plastid genomes and what do they encode?

A

→plastids possess their own genome, the plastome, and a specific machinery to decode its genetic information.

→plastid genomes encode proteins necessary for plastid function.

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5
Q

what are the four basic processes of multicellularity?

A

→spatial organisation
→change in form
→growth
→differentiation

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6
Q

describe why the evolution of the eye is thought of as being convergent

A

→The diversity of eyes suggests that they have evolved several times independently (polyphyletic, convergent evolution).

→they also have features in common.

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7
Q

what are the common features in eukaryotic eyes?

A

→ALL eukaryotes use a homologous family of proteins, opsins, to detect light.

→Opsins are G-protein coupled receptors that convert light to nerve impulses.

→Eukaryotic opsins share sequence homology and have diverged to detect different wavelengths of light.

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8
Q

what are homologues, paralogues and orthologues?

A

→Homologues are related by descent from a common ancestor.
→Paralogues are homologues within the same species.
→ Orthologues are homologues between species.

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9
Q

how many Hox genes do vertebrates have and how have they arisen?

A

→Vertebrates have four Hox gene clusters

→which have arisen from two duplication events of an ancestral chromosome.

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10
Q

what does Pax 6 have to do with the development of the eye?

A

→Being eyeless is orthologous to Pax6 in humans and mice.
→The ectopic (differently placed) expression of the eyeless gene in drosophilia (fruit flies) leads to ectopic eyes.
→Pax6 is involved in eye development throughout the animal kingdom.

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11
Q

how can eye loss occur as a result of evolution? and give an example

A

→some animals have evolved from surface-dwelling forms to underground forms

→Eye loss is a common feature in such animals because eyes are energetically expensive

→ Mexican, blind cavefish

→Its surface-dwelling ancestor has eyes, but the derived, cave-dwelling form doesn’t.

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12
Q

why are there differences in morphology between animals which are genetically related?

A

→morphological differences are established during development.

→even though it’s reproductive, selective pressure acts on the adult form.

→animals share the vast majority of their genes, but the regulation of gene expression differs between them.

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13
Q

how do we know where Homo-sapiens come from?

A

→We can get evidence from the fossil record and from molecular analyses.

→Mitochondria are maternally inherited.

→The mitochondrial genome replicates independently of the nuclear genome and does not undergo recombination

→the male Y chromosome does not have a homologous female chromosome to recombine with.

→Changes in sequence of mtDNA and the Y chromosome are due to random mutations over time.

→analysis of mtDNA and Y chromosome sequence shows maternal and paternal origin, respectively.

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14
Q

what is the RNA world hypothesis?

A

→ early life is thought to have been based on self-replicating and self catalyzing RNA molecules

→ catalytic RNAs are present in organisms from bacteria to humans

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15
Q

why did RNA world evolve into DNA?

A

→DNA is more stable than RNA

→ there is a greater range of protein enzymes and they are more robust

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