Ex2 Antbx

Question 1

DOC MSSA

Answer 1

Nafcillin or oxacillin

Question 2

Pt with MSSA has gram - growing

Answer 2

Cefazolin

Question 3

Only cephalosporin that covers MRSA

Answer 3

Ceftaroline

Question 4

Which drug class does not cover enterococcus at all?

Answer 4

Cephalosporins

Question 5

Pt has PCN allergy. Needs skin flora coverage and gram -

Answer 5

Levofloxacin

Question 6

Option for PNA

Answer 6

Levofloxacin

Question 7

Levo/Cipro are not good option for

Answer 7

Invasive MRSA

Question 8

DOC MRSA

Answer 8

Vancomycin

Question 9

Pseudomonas coverage

Answer 9

Zosyn
Ceftazidime
Carabenems (except ertapenem)
Aztreonam
Fluoroquinolones
Polymixin

Question 10

Covers Cdiff

Answer 10

Metrondiazole

Question 11

Covers MRSA, VRE, gram -, anaerobes

Answer 11

Tigecycline

Question 12

Any operations above lungs, need anaerobe coverage

Answer 12

Clindamycin

Question 13

Any operation below lungs that covers anaerobes

Answer 13

Metrondiazole

Question 14

DOC for Nectrotizing fasciitis

Answer 14

Clindamycin

Question 15

Which antbx can cause Cdiff?

Answer 15

Clindamycin

Levo/Cipro

Question 16

Pt allergic to PCN/Beta Lactam, on Clinda, has gram - bacteria during head/neck op.

Answer 16

Aztreonam

Question 17

Prolong QTc

Answer 17

Levo/Cipro
“Mycins”
Voriconazole

Question 18

Seizure risk in which medications?

Answer 18

Beta-lactams

Question 19

Agitation/hallucination is a risk in which medications?

Answer 19

Levo/Cipro

Question 20

How often are antibiotics re-dosed in the OR?

Answer 20

2x half life

Question 21

Example: how often is zosyn dosed in OR?

Answer 21

2x half life — normally q6; give q3 hours

Question 22

Skin flora coverage

Answer 22

Cefazolin

Question 23

Skin flora coverage (PCN allergy)

Answer 23

Clindamycin or Vancomycin

Question 24

GI/GU procedure, DOC

Answer 24

Cefazolin + metronidazole

Question 25

GI/GU procedure, DOC (PCN allergy)

Answer 25

Aztreonam + metrondiazole +vancomycin | OR Levofloxacin + metrondiazole

Question 26

SSI definition

Answer 26

Within 30 days | Within 90 days if prosthetic placed

Question 27

DOC VRE

Answer 27

Daptomycin, Linezolid

Question 28

Enterococcus DOC

Answer 28

Ampicillin

Question 29

Enterococcus DOC; PCN allergy

Answer 29

Vancomycin

Question 30

Time dependent antibiotics

Answer 30

Penicillins, cephalosporins, carbapenems, aztreonam

Question 31

Concentration dependent antibiotics

Answer 31

Aminoglycosides, daptomycin, metronidazole

Question 32

AE Aminoglycosides

Answer 32

Renal dysfunction

Question 33

AE Beta Lactams

Answer 33

Seizures | Drug fever

Question 34

Increases risk of Cdiff

Answer 34

Fluoroquinolones | Clinda

Question 35

AE Fluoroquinolones

Answer 35

Agitation/hallucination | Prolonged QTc

Question 36

AE Linezolid

Answer 36

``` MAOI Intxn (anything with serotonin increases risk SS) Dec. Bone Marrow/platelets ```

Question 37

AE Flagyl

Answer 37

Dark urine- ok

Question 38

AE Polymixin

Answer 38

Acute neuromuscular blockade