Ex2 IAs Theories Flashcards Preview

Pharm Fall 2019 > Ex2 IAs Theories > Flashcards

Flashcards in Ex2 IAs Theories Deck (10)
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1
Q

MAC of volatile substance is inversely proportional to lipid solubility

A

Meyer-Overton hypothesis*

2
Q

In terms of Meyer-Overton hypothesis, high MAC = ______ potency

A

low*

3
Q

Potency correlates with lipophilicity

A

Meyer-Overton Hypothesis*

4
Q

Amnesia is from what?

A

probably not spinal cord mediated

5
Q

inhaled anesthetics act by effects at multiple sites

A

multiple theory of narcosis*

6
Q

anesthetics act on no more than 2-3 sites to produce a specific effect

A

Unitary Theory of Narcosis

7
Q

Anesthesia is produced by membrane bound protein intx in brain/spinal cord

A

Protein Based Mechanism

8
Q

Protein Based Mechanism

Brain

A

GABA-A

9
Q

Protein Based Mechanism

Spinal Cord

A

Glycine, NMDA, Na Channel

10
Q

MOA N2O

A

NMDA Antagonism

Potassium 2P-Channel stimulation