Exam 1

Question 1

Which is an example of a dehydration reaction?

Answer 1

A fatty acid bonding to glycerol as a triglyceride is made

Question 2

What is found in olive oil?

Answer 2

Triglycerides with unsaturated fatty acids

Question 3

What do starch and cellulose have in common?

Answer 3

Both are polysaccharides and made by plants

Question 4

How does an atom become positively charged ion of the same element?

Answer 4

By losing an electron

Question 5

A covalent bond is most likely to be polar when

Answer 5

One of the two atoms is much more electronegative than the other

Question 6

Nitrogen is much more electronegative than hydrogen. Which of the following is true of ammonia?

Answer 6

Each hydrogen has a partial positive charge; the nitrogen has a partial negative charge

Question 7

What needs to be analyzed in order to determine if J. Merrick (the elephant man) had Proteus syndrome?

Answer 7

DNA from overgrown areas of his skeleton

Question 8

Which of the following is not true of a controlled experiment?

Answer 8

All variables are kept constant

Question 9

An atom has 7 protons, 7 neutrons and is electrically neutral (is not charged). How many electrons are in its valence shell?

Answer 9

5

Question 10

The surgery group lost an average of 50 pounds, and the non-surgery group lost an average of 43. What can we conclude?

Answer 10

We can’t tell until we run a statistical test

Question 11

What is the independent variable in the weight study?

Answer 11

Bariatric surgery

Question 12

Scientific process?

Answer 12

Make observations, ask questions, develop a hypothesis, collect and analyze data, make a conclusion

Question 13

Which type of molecule provides the genetic instructions for all living organisms?

Answer 13

DNA

Question 14

Which of be following is NOT a feature shared by all living organisms?

Answer 14

Made of Eukaryotic cells

Question 15

What is the dependent variable of the weight study?

Answer 15

Weight

Question 16

What is the control of the weight study?

Answer 16

The non surgery group

Question 17

An atoms identity is determined by

Answer 17

The number of protons present

Question 18

How should the data be interpreted by the graph?

Answer 18

No conclusion can be drawn until a statistical test is carried out

Question 19

An atom has 7 protons, 7 neutrons and is electrically neutral. What is its atomic mass?

Answer 19

14

Question 20

In the predation experiment we discussed in class, what was the independent variable?

Answer 20

Camouflage/contrast

Question 21

“With a dramatic genetic discovery”. What type of molecule was analyzed in this study?

Answer 21

DNA

Question 22

Which of the following molecules contains one or more polar covalent bonds?

Answer 22

H2O

Question 23

Cellulose is made up of?

Answer 23

Glucose

Question 24

Which of the following is/are true of the triglycerides in butter?

Answer 24

They have saturated fatty acids

Question 25

What is a hydrolysis reaction?

Answer 25

Using water to break a bond

Question 26

The partial negative charge at one end of a water molecule is attracted to a partial positive charge on another water molecule. What is this attraction called?

Answer 26

A hydrogen bond

Question 27

In Proteus syndrome experiment, what was the hypothesis being tested?

Answer 27

That a mutation was responsible for overgrowth

Question 28

A hypothesis is best described as

Answer 28

A possible explanation or answer

Question 29

Which of the following is/are true about hemoglobin?

Answer 29

It transports oxygen, contains iron, has a quaternary structure

Question 30

Which overactive and mutant protein is targeted by PLX4032?

Answer 30

BRAF

Question 31

Which interactions are primarily responsible for the primary structure of a protein?

Answer 31

Peptide bonds

Question 32

What is the purpose of a phase 1 clinical trial?

Answer 32

Safety

Question 33

Which cell type divides without regulation in melanoma?

Answer 33

Melanocytes

Question 34

Which of the following is responsible for the formation of alpha-helices?

Answer 34

Hydrogen bonds between atoms of the backbone

Question 35

A denatured protein has lost..?

Answer 35

It's three dimensional shape, and it's secondary and tertiary structure

Question 36

Which of the following is an avoidable risk factor for melanoma?

Answer 36

Sun exposure

Question 37

What is the sun protection factor of melanin in a tan?

Answer 37

3-5

Question 38

Which protein is secreted by the pancreas and helps regulate blood sugar?

Answer 38

Insulin

Question 39

What is extreme heat likely to do to proteins?

Answer 39

Denature them

Question 40

An alpha helix is a type of ______ structure?

Answer 40

Secondary

Question 41

Which of the following best describes the primary structure of a protein?

Answer 41

The order of amino acids

Question 42

In a phase three clinical trial of a cancer drug, what is the independent variable?

Answer 42

The treatment

Question 43

What can a person do to decrease their risk of melanoma?

Answer 43

Get regular skin checks, avoid tanning beds, wear sunscreen and protective clothing

Question 44

In a phase 1 clinical trial, who gets the investigational drug?

Answer 44

Everybody

Question 45

What does PLX4032 do?

Answer 45

Inhibits mutant BRAF in melanoma cells

Question 46

In a phase three clinical trial, how are participants assigned to each group?

Answer 46

Randomly

Question 47

What is the purpose of a phase 2 clinical trial?

Answer 47

To determine whether or not a new drug works

Question 48

In a phase 3 cancer treatment trial, which group gets the placebo?

Answer 48

Neither control nor experimental

Question 49

What is the purpose of blinding in a phase 3 trial?

Answer 49

To prevent bias

Question 50

In the melanoma study, which patients have a greater response rate to PLX4032?

Answer 50

Those with earlier stages of melanoma