Exam 1 Flashcards
(62 cards)
hemoglobin
polypeptide oxygen carrier
- alpha and beta chain
- heme group (poriphrin rings)
- a2b2 and Fe2
- protein
gastric pits
mucous cell, chief cell, parietal cell
-make enzymes for digestion and control ph
isotopes
atoms of an element that possess a different number of neutrons
- deuterium- 1p and 1n
- hydrogen- 1p and 0n
- tritium- 1p and 2n
ions
create neutral atoms by gain or loss of electrons
condensation
removes oh and h during synthesis and forms water
-dehydration synthesis
hydrolysis
breaks a covalent bond by adding oh and h
pH
- buffer system to stabilize (binding and releasing of H)
- phosphate, proteins, bicarbonate
- dissolving CO2 in water?
carbohydrates
-energy storage (structure in plants)
- C, H, O in 1:2:1 ratio
monosaccharides- glucose, galactose, and fructose (simple sugars)
disaccharides
polysaccharides (polymers of)
nucleic acid
-information, including heredity
- Chromosomes, DNA, RNA
polymers of nucleotides
protein
-polymers of amino acids
-structure, transport (active and passive), catalytic, signals, and receptors
3-4 levels of molecular structure:
-hemoglobin
-carbonic anhydrase
-succinate dehydrogenase
-phosphofructokinase
protein structures
primary- peptide bonds
secondary-alpha helix or beta sheet (motifs are similar ones BAB and helix turn helix)
tertiary- 3 dimensional alpha and beta
domains- functional regions of tertiary structures
misfolded proteins that are resistant to degradation
kuru mad cow- prp alzheimer’s- beta-amybid chronic wasting disease parkinson’s- a-synuclein
functions of protein
- kinases and add phosphate
- immunoglobulins antibodies
- toxins (snake venom)
- circulating transporters (hemoglobin and myoglobin)
- support fibers (collagen, keratin, fibrin)
- motion- muscle (actin and myosin)
- storage-calmokylin
transport proteins
aquaporin- lets water through
permease- moves glucose by facilitated diffusion
carries o2 and co2 in the blood (can hold 4 oxygen)
carbonic anhydrase
aids in co2 transport and release, has Zn in active site
-protein
phosphofructokinase (protein)
control of glucose catabolism
-high levels of ADO stimulates enzyme
-ATP inhibits
(pfk)
succinate dehydrogenase
only functional when in cell membrane; oxidizes molecules in citric acid cycle (succinate>fumerate)
- enzyme in membrane; isolate incompatible regions
- isolate krebs cycle enzymes in mitochondria membrane from acidic H on outside
keratin and collagen (protein)
keratin- hair strand and fingernails
collagen- cartilage
channels
open- potassium leak channel aquaporin (h2o) gated- sodium, potassium, and calcium ion -important in neural signaling
membrane transport
- phospholipid bilayer (plasma membrane)
- oxygen can diffuse through but others need channels
- simple and facilitate diffusion and passive transport
pumps
- require energy given by hydrolysis (atp)
- uses energy to move ions across membrane gradient
- change shape
DNA
encodes information used to assemble mRNA and specifies the primary structure of proteins
- 2 deoxyribose, phosphate, nitrogen bases
RNA
- single stranded
- pentose ribose and phosphate and nitrogen bases
neutral lipids
- glycerol and fatty acids
- saturated and unsaturated
- energy
- triglycerides (glycerol and 3 fatty acids)