Exam 1: Ch 1 Flashcards

(46 cards)

1
Q

charles darwin

A

natural selection: organisms vary randomly and compete within their environment for resources

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2
Q

what are genes?

A

strands of DNA that code for proteins

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3
Q

mutation

A

an alteration in the structure and organization of a gene

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4
Q

metazoan definition

A

multicellular animal

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5
Q

water accounts for how much of a cell’s volume?

A

75%

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6
Q

ATP

A

adenosine triphosphate

cell’s primary source of energy

energy stored in two of its chemical bonds

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7
Q

ADP

A

adenosine triphosphate

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8
Q

photosynthesis

A

plants and some organisms harvest energy from the sun

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9
Q

proteins are commonly made of how many aas?

A

100-1000

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10
Q

enzyme

A

protein that catalyzes chemical reactions without being consumed or changed

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11
Q

cytoskeletal proteins

A

structural components of a cell that form an internal skeleton

also power movement of structures using ATP

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12
Q

when did Watson & Crick propose the structure of DNA

A

60 yrs ago

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13
Q

2 regions of genes

A

coding region: aa sequence of a protein

regulatory region: binds specific proteins and controls when and in which cells the protein is made

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14
Q

how many genes do humans have

A

~ 20,000-23,000

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15
Q

transcription

A

coding region of a gene is copied into mRNA by RNA polymerase

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16
Q

RNA polymerase

A

large enzyme that catalyzes that linkage of nt into RNA using DNA as a template

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17
Q

translation

A

ribosome reads mRNA and translates a protein

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18
Q

transcription factor

A

DNA-binding proteins that alter gene expression

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19
Q

what are phospholipid bilayers impermeable to

A

water

ions

hydrophillic small molecules

20
Q

4 kingdoms of eukaryotes

A

plants

animals

fungi

protists

21
Q

5th and 6th kingdoms

A

bacteria

archae

22
Q

model organisms

A

systems in which the study of cellular function and development serve as a model for other species

23
Q

bacteria basics

A

1-2 micrometers

plasma membrane, cell wall (peptidoglycan) cytoplasm, circular DNA chromosome, ribosomes in cytoplasm, mesosome (invagination)

24
Q

gram neg/pos

A

neg: inner cell wall & outer membrane separated by periplasmic space
pos: thicker cell wall and no outer membrane

25
archae extreme conditions?
yes
26
eukaryote basics
10-100 micrometers plasma membrane, organelles, membrane enclosed nucleus, mitochondria (chloroplasts in plants)
27
lysosome
organelle with a lower pH 5.0 break down parts of the cell into small molecules
28
cytoskeleton
gives cell strength and rigidity cell shape
29
cytoskeleton fibers
microtubule: 20nm, protein tubulin intermediate filaments: 10nm, rod-shaped subunits microfilaments: 7nm, protein actin
30
cell-adhesion proteins
animal cells are glued together
31
basal lamina
tough matrix of proteins and polysaccharides forms a supporting layer underlying cell sheets and prevents cell aggregates from ripping apart
32
plasmodesmata
cytoplasmic bridges in some plants
33
endothelium
layer of endothelial cells prevent blood cell from leaking out of vessels
34
protostomes
develop a mouth close to a transient opening in the early embryo (blastopore) have a ventral nerve chord worms insects mollusks
35
deuterostomes
develop an anus close to this transient opening in the embryo have a dorsal central nervous system echinoderms and vertebrates
36
patterning genes
specify the general organization of an organism beginning with major body axes conserved in both protostomes and deuterostomes as master transcription factors eyeless in fruit flies and pax6 in humans are genes for eye development
37
virus
protein coat covering a core of genetic material
38
evolution
genetic change in a population over time through evolution all organisms are related in a family tree
39
which isomer of aas are found in proteins
L, not D
40
mesosome
bacterial invagination of cell membrane associated with synthesis of DNA and secretion of proteins
41
peptidoglycan
complex of proteins and oligosaccharides that make up the cell wall of bacteria
42
E. coli as a model organism
grow rapidly, possess mechanisms for controlling gene regulation have proteins involed in DNA, RNA, and protein synthesis
43
peroxisome
small organelle specialized for breaking down lipid components of membranes
44
endoplasmic reticulum
organelle that produces, processes, and ships proteins and lipids usually ship to golgi complex
45
golgi complex
organelle that modifies proteins and lipids before transporting to final destination
46
yeast as a model organism
identification of many proteins that regulate cell cycle and catalyze DNA replication/transcription grow easily and clones have same genes and biochemical properties