Exam 1: Hematopoiesis stuff Flashcards Preview

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Flashcards in Exam 1: Hematopoiesis stuff Deck (13):
1

Define hematopoiesis.

Blood cell development and production

2

What 4 structures in the body are involved in hematopoiesis?

1. Bone marrow
2. Spleen
3. Lymph nodes
4. Thymus

3

Describe the development of hematopoiesis at this stage:

2 weeks old

- yolk sac
- primitive (erythroblast)

4

Describe the development of hematopoiesis at this stage:

2 months old

liver and spleen

5

Describe the development of hematopoiesis at this stage:

7 months old

- bone marrow
- most bones are filled with erythroid cells

6

Describe the development of hematopoiesis at this stage:

Birth

- hematopoiesis stops in the liver and spleen
# now only occurs in bones
- about 90% of bone marrow is active (red)

7

Describe the different types of bone marrow.

1. Red
# active
2. Yellow
# inactive
# adipocytes

8

Describe the development of hematopoiesis at this stage:

4 years old

- long bones (ex: femur, tibia) begin having fat cells
- inactive/yellow

9

Describe the development of hematopoiesis at this stage:

18 -- 20 years old

- hematopoiesis is reduced to 60% active/red
# sternum
# ribs
# pelvis
# vertebrae
# skull
- the rest is 40% inactive/yellow

10

Describe the development of hematopoiesis at this stage:

40 years old

- hematopoiesis is reduced to 50% active/red
- thus, fat and red marrow are equal in these areas:
# sternum
# ribs
# pelvis
# vertebrae
# skull

11

Describe the development of hematopoiesis at this stage:

>55 years old

- hematopoiesis is reduced to 40% active/red in these areas:
# sternum
# ribs
# pelvis
# vertebrae
# skull

12

Where is the best spot for retrieving bone marrow?

iliac crest

13

Explain extramedullary hematopoiesis.

- when bone marrow stops doing all the work
- the liver/spleen kicks back into action just like old times