Exam 1; Neoplasia I Flashcards Preview

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Flashcards in Exam 1; Neoplasia I Deck (19):
1

This type of neoplasm remains localized, cannot spread to other sites, generally amenable to surgical removal and patient survival

benign neoplasm

2

This type of neoplasm has the potential to invade and destroy adjacent normal tissue and spread to distant anatomic sites. Often leads to death of the patient especially without treatment

malignant neoplasm

3

This refers to the transformed or neoclassic cells; the parenchymal component determines the biologic behavior of the particular neoplasm, and it is this component from which the neoplasm derives its name

parenchyma

4

This refers to the supporting tissue of the tumor - the non-neoplastic blood vessels and connective tissue supplied by the host

stroma

5

Which suffix is worse -oma or -sarcoma

-sarcoma; thats used for malignant
-oma; used for benign

6

What are malignancies of epithelial origin called

carcinomas

7

This refers to the degree to which the parenchymal tissue or a neoplasm resembles the parent tissue, both functionally and morphologically

differentiation and anaplasia

8

What is meant by that benign neoplasms are generally well defined

the parenchymal cells bear a strong resemblance to the tissue from which the tumor arose

9

Malignancies composed of poorly differentiated cells are described as what

anaplastic

10

This is characterized by pleomorphism, nuclear hyperchromatism, an increased nuclear/cytoplasmic ratio compared to normal cells, atypical nuclei, and numerous and atypical mitoses

anaplasia

11

This refers to an altered growth pattern, usually referring to epithelium that is not neoplastic but may become cancerous eventually

dysplasia

12

The most severe epithelial dysplasia is referred to as what, it as all the microscopic features of cancer, but the atypical cells have not invaded into the host

carcinoma-in-situ

13

the better the degree of differentiation of a neoplasm, the more it does what

completely retains the functional capabilities of the tissue from which it arose

14

Benign tumors generally grow fast or slowly

slowly

15

What is the growth rate of malignant neoplasms

highly variable; depends on the type of tumor
some may grow so quickly that they outgrow the blood supply which would explain necrosis

16

Benign tumors tend to have this, which is essentially a compressed band of fibrous connective tissue at the periphery of the tumor

a capsule

17

What are the three ways in which cancers grow

progressive infiltration
invasion
destruction and penetration

18

This quality is the most reliable means for distinguishing the malignant nature of a tumor

infiltrative quality

19

What is the best indicator of a malignancy

the presence of metastasis