EXAM 1 REVIEW (Unit 4) Flashcards

1
Q

Who discovered the DNA double Helix and X-ray diffraction?

A

Rosalind Franklin

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2
Q

DNA uncoiled is called

A

chromatin

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3
Q

Chromatin is __________ DNA

A

compacted

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4
Q

Chromatin is composed of DNA wound around _______

A

protein

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5
Q

DNA is made from a _______________

A

pair of nucleotides

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6
Q

What does a nucleotide consist of?

A
  1. Base (G,C,A,T)
  2. Phosphate
  3. Sugar (deoxyribose)
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7
Q

______ serves as code for amino acids

A

DNA

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8
Q

Put a bunch of amino acids together and you get a _________

A

polypeptide

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9
Q

what is a genome?

A

all the genes of one person (humans have estimated 35,000 genes)

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10
Q

DNA never leaves the _________

A

nucleus

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11
Q

the library of information stored in DNA can only be copied. This is done by _______

A

m-RNA

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12
Q

protein is created by this pathway: __________

A

DNA to RNA to protein

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13
Q

genetic information flows only in one direction: DNA to RNA to PROTEIN. this is called _____________

A

central dogma

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14
Q

Genes control the production of _________

A

proteins

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15
Q

what is t-RNA?

A

transfer RNA.
-it looks like a big “T” with three bases called an anticodon

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16
Q

what is m-RNA?

A

Messanger RNA
- looks like a single ribbon (single helix)
-three bases attached are called a codon

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17
Q

what is r-RNA?

A

Ribosomal RNA.
-its two proteins combined together
-looks like a fist with the other hand wrapped around it

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18
Q

Transcription occurs in the _______

19
Q

______ transcribes DNA into its own code

20
Q

in protein synthesis, transcription =

A

DNA transcribed to m-RNA

21
Q

in protein synthesis, translation =

A

m-RNA translated by t-RNA on rough ER into a protein

22
Q

ribosomes are also called _______

23
Q

what comes first? transcription or translation?

A

transcription

24
Q

what do enzymes do?

A

speed body reactions and are proteins

25
what happens in an enzyme reaction?
the enzyme assists in the reaction but is not used up
26
enzyme activity can be controlled by ________ (pHIT)
pH, inhibitors, and temperature (pHIT)
27
What are the three main phases in the cell cycle?
Interphase, mitosis, and cytokinesis
28
What are the 3 stages in interphase?
G1 phase (first growth) S phase (synthesis) G2 phase (second growth)
29
Is mitosis a part of interphase?
No, it is its own phase
30
is cytokinesis part of interphase or mitosis?
no
31
Mitosis is nuclear division and consists of four phases: _________
-Prophase -Metaphase -Anaphase -Telophase
32
what is a genotype?
your genetic makeup
33
what is the outward expression of the gene? (like a photo)
Phenotype
34
when you have two identical alleles, or the same trait (PP or pp) what is it called?
homozygous
35
when you have different alleles (Pp) what is this called?
heterozygous
36
what causes death and is usually homozygous recessive?
lethal allele (or the lethal gene)
37
What is a helpful way to determine genotype?
the Punnett square
38
what are the three variations on inheritance?
Codominance, Incomplete dominance, and polygenic inheritance
39
Name the variation on inheritance:____________ -Both heterozygous alleles are equally dominant - example: sickle cell anemia
codominance
40
Name the variation on inheritance: _________ - Both heterozygous alleles are expressed incompletely (not equally) - a _____ and ______ flowers create a pINk flower
incomplete dominance
41
Name the variation of inheritance: -continuous gradation of gene expression - eye color and kids skin color of dark and light skinned parents
Polygenic inheritance
42
Polygenic Inheritance: Genes at two or more loci, or even different chromosomes contribute to a _____________
single phenotypic trait (eye and skin color)
43
What is sickle-cell disease?
-A hereditary hemoglobin defect -effects mostly those of African decent -shortened life span