Flashcards in Exam 10: Marijuana and Stuff Deck (31):
Marijuana plant resin with super high TCH concentration
K-2 and Spice
Pharmacokinetics of Marijuana
Highly lipid soluble
Accumulates in fat and is slowly released over time
High dose effects of marijuana
Paranoia, hallucinations, psychosis
Marijuana cardiovascular effects
How might marijuana help with glaucoma treatment?
decrease intraocular pressure
How might marijuana help cancer patients?
Inhibition of vomiting reflex (antiemetic during chemo)
2. Lower testosterone
4. Lung damage
Medical uses of marijuana (3)
1. Prevention of nausea during chemotherapy
2. Prevention of "wasting" in AIDs
3. Glaucoma/asthma (data shows that it doesnt really work)
What is used in native american ceremonies to get high?
Salvinorin A is an agonist at kappa opioid receptors and D2 dopamine receptors
Hallucinogen (different from other hallucinogens somehow)
Plant from Thailand that is a stimulant/pain releiver
Similar to opioids, but different...
some use it for pain control or opioid withdrawal
What neurotransmitter disturbance is seen in Alzheimer's?
Decreased ACh in the nucleus basalts of Meynert
What drugs can be used to treat Alzheimer's neurotransmitter disturbance?
How effective are acetylcholinesterase inhibitors in treating Alzheimers?
Modest improvement in cognitive function in some, not much in other.
Do not slow the progress of the disease
Side effects of donepezil, rivastigmine?
Muscarinic stuff... (leaky)
Which acetylcholinesterase inhibitor causes less side effects?
also blocks excitatory glutamate at NDMA receptors in the hippocampus and frontal cortex
how do vitamin E, seligiline, and deprenyl help with alzheimers
(controversial aka probably complete bullshit)
What is the only drug that treats ALS?
inhibits excitatory glutamate
Mainstay drug of ADHD therapy
reserved for patients who don't respond to methylphenidate
can complicate prescribing
inhibits NE reuptake
benefits ADHD patients who don't respond well to or tolerate stimulants
not as effective in most people though