Exam # 2 Flashcards

Includes: Equine Nutrition, Ruminant Nutrition, Swine Nutrition, Food and Feedstuffs, Pet food Labels, Dog and Cat Nutrition (359 cards)

1
Q

What occurs with the levels of antibodies in the sows milk? What happens to the piglets ability to absorb antibodies?

A

Decreases rapidly over first 24 hours. Antibodies half over first 4 hours. Composition rapidly changes in first 24 hours. Piglets ability to absorb antibodies reduces rapidly. Piglets are capable of very high intakes of colostrum

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2
Q

What can occur in Vitamin A deficiency?

A

Deficiency
– Impaired Growth
– Reproductive Failure
– Dermatoses
– Mucus membranes damage
– Immune deficiency

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3
Q

What can occur in vitamin E deficiency? What can occur in vitamin E excess?

A

• Deficiency
– Reproductive failure
– Pansteatitis in cats
• Fed diet high in PUFA’s with insufficient Vit E (Tuna Diet) ( inflammation in their own fat, and cause pain. This is due to oxidative damage)
• Excess
– Possible increase need for Vit A and Vit D

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4
Q

What occurs with calcium in acidosis?

A
  • Less calcium is bound, causing the release of calcium from the bones. Calcium from bone can also be used as a buffer.
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5
Q

What occurs with Vitamin E and Selenium?

A

Synergistic effect as antioxidants (low amounts in one require
supplementation of the other)

• Prevent lipid peroxidation in the cell membranes- glutathione
peroxidase

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6
Q

What is excess glucose called in cats? What is true about cats ability to utilize glucose?

A

Excess glucose in cats: galactosemia and galactosuria

– Less efficient dietary sugar use
– Although they are constantly in gluconeogenesis

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7
Q

What else is important when looking at a food label on pet food?

A

Don’t get hung up on the ingredient
list!
• In most cases, nutrients are more important than ingredients
• The ingredient list provides
ingredients in the order of their
weight before processing
• Can be manipulated to make the listlook more appealing
– For example: Don’t like corn to be high on your list? Use some corn and some corn gluten meal – Just like that- its lower on the list!

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8
Q

What do horses eat?

A

Grass- good for digestion
Hay/ Haylage - Provides fiber (satiates + gi motility working) particularly in cooler months when pasture is unavailable.
Fruit and veggies- add moisture to feed
Concentrates: concentratead energy source
Salt : good to offer to help replenish electrolytes.

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9
Q

How much glucose is needed to produce milk? What does that mean for cows? What is the most common milk cow in the US? How many lbs of milk can a cow make in a day? When is another time the reqiures more glucose?

A
  • 2 lbs glucose needed to make 6 gallons of milk.
  • Liver is in state of constant gluconeogenesis during lactation and requires constant supply of propionate.
  • Can make 150 lbs of milk (18 gallons) per day.
  • Requires more glucose during third trimester of gestation.
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10
Q

What are the physical signs of malnutrition? What should you do if you suspect malnutrition? What are the levels of risk of nutrition related problems?

A
  • Weight loss and Muscle loss
  • Determine adequacy of the current diet for the physiological status of the animal
    • Estimate risk of nutrition related problem
    – High
    – Moderate
    – Low
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11
Q

What are the effects of excessive air speed for pigs?

A

Excessive air speed causes
• Reduced effective temperature
• Incorrect lying behaviour
• Vices such as tail-biting

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12
Q

What is the effect of panting? Why do dogs pant? What can occur if a dog becomes dehydrated?

A
  • Dogs don’t sweat (much)
  • Most water loss is through evaporation
  • Not much sodium is lost in drool saliva
  • Dehydration may quickly lead to plasma hyperosmolality
  • Added electrolytes to water -> hyperosmolality is not corrected
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13
Q

What is Mg necessary for?

A

Adenyl cyclase activity, which is required for parathyroid hormone release. ( Which is important for absorption of calcium)

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14
Q

What is important to remember about cats ability to break down carbohydrates?

A
  • Low activity of enzymes that break down CHO such as amylase
    • Low adaptability of glucose transporters in the intestines (if meal is high in glucose, not all of it will be absorbed and remainder can cause fermentation, and water loss in intestines)
    • Glucose is absorbed via Na dependent transmembrane
    mechanism as well as passive diffusion
    • Fructose is Na independent
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15
Q

What can cause low colostrum production in swine?

A

MA (Mastitis/Metritis/Agalactia) may cause failure or low production

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16
Q

Where are starches, simple sugars, proteins, vitamins, and minerals found? Where is fiber found? What has a high content of starch?

A
  • STARCHES AND SIMPLE SUGARS, AS WELL AS PROTEINS, VITAMINS, MINERALS, ARE FOUND IN THE PLANT CELL’S CYTOSOL WHEREAS FIBER COMPRISES THE CELL WALL AND SOLUBLE FIBER IS IN THE INTERCELLULAR SPACE FORMING A MATRIX THAT HOLDS CELLS TOGETHER
  • SEEDS (GRAINS) HAVE A HIGH CONTENT OF STARCH. THEY HAVE AN OUTER LAYER THAT NEEDS TO BE BROKEN
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17
Q

What are age related factors in geriatric factors that decrease their ability to adapt? What should you do to make sure you are providing optimal nutrition?

A

• Changes in body composition and metabolic rates • Decreased ability to adapt to:
– Excess – Deficiency – Nutrient Quality – Intake
• Special Senses
• Evaluate individually

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18
Q

What are the symptoms and mechanisms occuring with low iodine? High iodine?

A

Iodine is important to make triiodothyronine and thyroxine.

Low iodine -> low thyroid hormone production

Excess iodine -> negative feedback for TSH release from pituitary -> Low thyroid hormone production.

You can also see Goiter and hypothyroidism in these patients.

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19
Q

What is important to remember when feeding the critically ill horse?

A

 There are little data on feeding hospitalized horses and its
association or effect on morbidity and mortality
 However, plenty of data exists in people and other species to demonstrate that a catabolic state reduces prognosis
 Nutritional intervention should be considered if the horse is
not fed for longer than 48 hours in an animal with good
physiological status
 Less if obese, underlying metabolic disease, growing or
very sick
 Enteral nutritional support: a nasogastric feeding tube can be
passed and used temporarily, or an indwelling esophageal
feeding tube can be placed  The horse should be checked for gastric reflux before feeding

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20
Q

What are some examples of diseases seen in pomeranians?

A

Pomeranian- picky eater, dental disease

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21
Q

What is a good energy source for animals who are not being exercised (in terms of geriatric horses)? How should the food be prepared and what should be avoided?

A

If there are no contraindications: oil as an energy source rather than cereal starch - especially for those animals not being exercised

 If any cereals, other than oats, are fed make sure they are processed by cooking (e.g., steam flaking, micronizing) to make the starch more easily digested, reducing the risk of starch overload
 Avoid feeding large grain-based meals: restrict meal sizes

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22
Q

Will sports drinks be helpful ?
Do antioxidants help working dogs? Creatine? BCAA?

A

Sports drinks: Not really
Antioxidants: Unknown
Creatine: No proven benefit
BCAA: Probably enough, not enough to help

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23
Q

What is the ideal BCS for a horse at rest/ maintenance? What is their Daily energy requirement?

What about a performance horse?

What about a horse who completes ranch work?

A

Rest / Maintanence: 4-6 (0.33 x kg bodyweight)

Performance: 5-6 ( 1.4 x (DER for rest))

Ranch work: 4-5 (1.6 x (DER for rest))

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24
Q

When will adult maintenance diets not be ideal for patients?

A
  • Kidney
  • Pancreatitis
  • Gastrointestinal
  • Adverse reaction to food
  • Critical patient
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25
What is grass tetany? What is the clinical signs?
* Graze lush pastures can lead to hypomagnesemia. * Clinical signs: repetitive muscle contractions that are uncontrolled, hyperirritability and convulsions. * Start with muscle tremors and progress to tetany. Clinical signs by stage: Early: Muscle fasiculations, hyperesthesia, stiff goose stepping gait. Animal may be irritable or maybe aggressive. Can be bellowing with an overly alert , nervous expression Later: Recombency and convulsion, paddling motions with limb, extensor rigidity, opisthotonus, death can occur from respiratory/ cardiac arrest.
26
What occurs when a horse has excess protien? What kind of process is protien metabolism?
• Rare • Increased heat production • Protein is thermogenic • Can be a problem in hot climate or during performance • Can lead to ammonia smell in the urine • Expensive • Could lead to obesity? • Possibly increased growth in juvenile horses? - Protein metabolism is thermogenic, so their could be increased heat production in preformance horses.
27
What percent of minerals in the body accounts for calcium and phosphorus? What is Phos important for? What is calcium important for? What is the storage pool for these minerals and how does the blood level remain constant ?
• Calcium and phosphorus comprise 70% of all the minerals in the body. • The bone is the storage pool for these minerals (the ionized calcium in the blood remains constant by drawing from the bone if needed) • P is important for energy metabolism (ATP), membrane function and enzyme regulation • Ca is important for neural function, enzyme activity, cell signaling etc
28
What occurs with taurine deficiency? When was the first time it was recognized?
• Taurine deficiency in cats has been recognized since 1975 • Taurine-deficiency dilated cardiomyopathy (DCM) of cats represents a failure in contractility – presumably due to abnormal calcium-ion balance in the myocardial cell • Taurine deficiency impacts ability to regulate ionic flux in photoreceptor cells in the retina • When retinal taurine concentration is reduced structure and function deteriorate progressively
29
What would a donkeys typical diet contain?
- Typical diet would include wheat or barley straw or stover (leaves and stalks of crops such as corn) • Straw can be fed ad-lib - Low energy density
30
What is forage- pasture?
* PASTURE: PLANTS THAT ARE AVAILABLE FOR GRAZING * EITHER CULTIVATED (PLANTED) OR WILD (NATIVE) * MAY OR MAY NOT BE IRRIGATED
31
Why do we maximize intake during lactation?
This is because though the sow is taking in a normal amount of food her BCS will drop from increased energy expenditure, so we need to try to minimize that drop as much as possible.
32
What are the fat soluable vitamins?
- Vitamin K - Vitamin A - Vitamin D - Vitamin E
33
What can cause white muscle disease?
Vitamin E and Selenium deficiency
34
What are the clinical signs of heinz body anemia? What else can you see with heinz body anemia?
Clinical signs: Jaundice, dyspnea, tachycardia, hematuria, fatigue and hypotension. What will you see? - Excessive formation of Heinz bodies, and attachment to membranes increases their rigidity and renders them susceptible to fragmentation in the spleen. - They are the result of ROS which can cause intravascular lysis of RBCs leading to hemoglobinemia and hemoglobinuria. - Methemoglobinemia ( brown plasma) can occur in animals from oxidant induced injury of iron in hemoglobin (Fe2+ -\> Fe3+ producing methemoglobin) - Cats more susceptible than dogs, but its still highly unrecommended overall. No benefit of garlic.
35
What would the protien requirement be in first trimesters and the last? Why does that change? What is a good feed for a pregnant mare? What can you balance the feed with?
Protein requirement would increase to 8% in the first trimesters and 10% in the last trimester. this is because more protien is needed in the final trimester to produce the fetus' tissues and help support lactation. * High protein feed: legume grass, legume hay * Can balance a meal with grass hay and high protein grain (12% protein DM)
36
What are the clincial signs of white muscle disease?
Clinical signs • Lethargy • In foals- unable to curl tongue to suckle • May cause aspiration pneumonia – if tracheal muscles are affected Yellow fat disease- a condition that causes steatitis Steatitis- inflammation of fat stores.
37
What can you see that will lead you to a diagnosis of white muscle disease?
- Low Vitamin E concentration ( plasma levels can be variable) - Can biopsy liver and muscle stores (avoid fat stores, they are not reliable) - High Creatine Kinase, and AST (shows recent muscle damage) - Low RBC glutathione peroxidase (selenium deficiency)
38
What is Dry matter intake? What is dry matter intake used for? what is it expressed as?
KILOGRAM DRY MATTER (WATER REMOVED) IS SOMETIMES USED TO EXPRESS INTAKE. DRY MATTER INTAKE ESTIMATES ARE ALSO USED TO CALCULATE THERAPEUTIC INTERVENTIONS PROVIDED IN THE FEED • DAILY DRY MATTER INTAKE, EXPRESSED AS A PERCENTAGE OF MATURE BODYWEIGHT AT MAINTENANCE
39
What is aftermath? What is the term that is used to reference this?
• THE FORAGE THAT REGROWS IS CALLED AFTERMATH, STUBBLE, OR RESIDUE • IT IS A HIGH QUALITY, NUTRIENT RICH AND LUSH FORAGE. - Stubble is often the term used when referring to corn or other grain.
40
What are the breed related disease factors?
Breed associated diseases – Orthopedic – Obesity – Urinary stones – Food Hypersensitivity
41
What is the best way to determine hays quality? What other ways can you determine this?
Most reliable and most representative: Lab analysis (core biopsy) Other ways: - appearance, color, smell Be careful to make sure the hay is not bad on outside and good inside.
42
What should you provide to suckling piglets for water requirements?
* Access to fresh clean water via correctly positioned nipple or bowl- type drinker * Drain the water pipe system about 10 days after farrowing or link into sow line
43
Why do cats need taurine supplementation?
• Cats possess the entire enzymatic pathway to form taurine from methionine/cysteine • Two enzymes along the pathway have low activity (cysteine dioxygenase and cysteinesulphinic acid decarboxylase) - Too slow and does not allow for enough taurine to be made. • ‘Double Whammy’ – Low endogenous production of taurine – Loss of taurine in the bile
44
What is the difference between natural gestation periods, lactation periods, and growth periods vs. commercial farms?
The gestation timeframe is the same but the lactation period is more than 50% less and the growth timeframe is lessened as well
45
What is important for the diet requirements of the suckling foal? What is creep feed? What does it include?
• The main diet is the mare’s milk; however will show interest in other food such as the mare’s grain and creep feed • Creep feed: the feed that is offered to suckling animals (also beef, swine, small ruminants) to support growth in addition to milk • Creep feed would typically include corn, oat, barley
46
What do cats utilize amino acids for? What is the effect of cats being fed a limited protein diet?
• Amino acids are important to build protein and used as a source of energy and gluconeogenesis • Amino acids are also utilized to form ketoacids as substrates for energy or glucose production • Cats are unable to decrease the activity of transaminase/ deaminase enzymes when fed a limited protein diet • This is likely since cats are strict carnivores and adapted to high protein intake
47
What is vital for a piglets health? What age are piglets most susceptible to diarrhea? What can you do to help growth efficiency?
* Colostrum consumption is vital for the piglet’s health * Piglets in the ages of 3-6 weeks are most susceptible to diarrhea * Maintaining pigs at a thermoneutral environment can help growth efficiency
48
What are the important intermediates for the urea cycle?
Arginine Citruline Arginosuccinate Omithine
49
What is rumination? When does it occur?
* Rumination- regurgitation of ingesta from the reticulum followed by remastication and reswallowing. * Effective mechanical breakdown and increases substrate surface area to fermentive microbes. * Usually occurs when cow is at rest.
50
How are dogs muscles different from humans?
Dogs differ from human beings in that dogs are adapted for long-distance running using the aerobic metabolism of fat
51
What are the three different layers in the ruminant stomach? What is in each layer?
• 3 different layers. Gas is most dorsal. Then todays hay since it is not as broken down yet. Followed by grain and yesterdays hay (which has had some time to ferment and settle. Bottom Layer is higher in liquids and smaller particles.
52
What is parenteral nutrition? When is it used? What are its components?
 If the gut function is impaired, parenteral nutrition may be administered  The formula is custom made under a hood  Components used in formulating parenteral nutrition include:  protein in the form of amino acids  carbohydrates in the form of dextrose  lipids in the form of long chain fatty acids  May be safer to avoid in donkeys, ponies and other horses prone to hyperlipidemia  electrolytes and vitamins  The catheter, line and bag must be kept as clean as possible
53
In Nature: What kind of animals are pigs? What do they do the majority of their lives? How many piglets do they have?
- Omnivores - Exploration - 5-8 piglets
54
What is Hay? How is it collected, and what is good about the level of moisture in hay?
• HAY IS CUT FORAGE THAT IS DRIED AND HAS 90% DRY MATTER AND 10% MOISTURE • IT IS CUT AND COLLECTED IN BALES (SQUARE OR ROUND) AND STACKS • DUE TO LOW % MOISTURE, HAY CAN BE STORED FOR A RELATIVELY LONG PERIOD OF TIME WITHOUT MOLD OR PUTREFACTION
55
What kind of diet is given to dogs who are running alot and quickly? What kind of diet is given to dogs who are running more distance paced running?
1. ) High in carbohydrates 2. ) Diet with more fat.
56
What can occur in salt deficiency?
• Uncommon as long as salt is available • May cause weakness • Decreased sweating • Decreased performance • Decreased sweating • Decreased lactation • Pica
57
What are toxic foods for companion animals? Why is each one considered toxic?
- Avocado: toxic for birds( can cause respiratory signs in birds) (not dogs/ cats ( can be given but pit can cause obstruction) - Chocolate: Contains theobromine which dogs/cats). is an alkaloid that can cause a variety of clinical signs. Toxic doses of theobromine are as low as 20 mg/kg. You can see GI signs, cardiac, and neurologic signs. - More pure the chocolate - More toxic - Grapes / Rasins: Can cause kidney injury in dogs and cats. Toxin is unknown. Appears safe in birds/ reptiles in moderation. - Macadamia Nuts: Can cause weakness, depression, vomiting, tremors, and hyperthermia in dogs. Signs usually appear within 12 hours of ingestion and can last 12- 48 hours. - Allium species: ( garlic, onion, leek, chives) cause gastroenteritis and Heinz body anemia ( oxidative damage leading to hemolytic anemia) - Xylitol: Common sweetener in sugar free foods. Can cause insulin increase (hypoglycemia from increased insulin) and liver failure in dogs. Xylitol is metabolized by the liver and intermediates are phosphorylated and deplete ATP from hepatocytes. Can also cause oxidative damage. - Kabocha squash - can cause GI signs in dogs ( other pumpkins/ squash are fine) - Raw dough- not toxic but can cause GI obstruction - High fat foods: Not exactly toxic but can cause severe GI signs and pancreatitis in some dogs.
58
What is the National Research Counsel Minimal Requirement? What is the National Research Counsel Adequate Intake?
- NRC Minimal requirement- minimal concentration or amount of bioavailable nutrient that will support a defined physiological state • NRC Adequate intake - the concentration in the diet or amount required by the animal of a nutrient that is presumed to sustain any given life stage when no minimal requirement has been demonstrated
59
Which AAFCO statement is the " loophole"? 1. “X is formulated to meet the nutritional levels established by the AAFCO Dog (or cat) Food Nutrient Profiles for Y. 2. “Animal feeding tests using AAFCO procedures substantiate that X provides complete and balanced nutrition for Y.” 3. “X provides complete and balanced nutrition for Y and is comparable to a product which has been substantiated using AAFCO feeding tests”
Statement 3 - This particular product has not undergone a feeding trial. Gives company leeway of what is comparable.
60
What is a horses daily energy requirements? What % dry matter would allow horses to meet their daily requirement on good quality forage? What is their max DMI consumption per day?
Daily energy requiremet: 33 Mcal/100kg BW/day Daily needs DMI on good quality forage -\> 1-1.5 % BW DMI Max consumption DMI: 3-3.5 DMI
61
What are some lab tests that can be run on equine patients? What would they indicate in terms of diet?
Most nutrients cannot be adequately determined with lab tests/blood tests • Albumin- can be reduced if protein status is poor, acute inflammation or liver failure • Albumin half life is long (19.4 days) therefore may not reflect acute changes • Decreased creatinine/BUN can indicate poor muscling and protein intake
62
What is iron? Why do piglets need supplementation?
• Vital component of blood • Aids absorption and transfer of oxygen in blood • Piglet born with limited supplies. Milk contains no iron. Traditionally outdoor animals, obtain iron from the soil - Must give supplemental iron to prevent anaemia and loss of growth
63
What is the difference between fiber and starch?
• BOTH ARE POLYSACCHARIDES • ENDOGENOUS MAMMALIAN ENZYMES CANNOT BREAK 1,4 GLYCOSIDIC LINKAGE (ONLY ALPHA) IN CELLULOSE OR HEMICELLULOSE • BACTERIAL FERMENTATION ALLOWS DIGESTION OF THESE COMPOUNDS IN THE FORESTOMACH OR HINDGUT VIA FERMENTATION • MAMMALIAN AND BACTERIAL ENZYMES CAN DIGEST STARCH. WITH BACTERIAL FERMENTATION THESE STARCHES EVENTUALLY FORM VOLATILE FATTY ACIDS (VFA)
64
What are the clinical signs of rhabdomyolysis?
Muscle pain • Swollen muscles  Stiff gait  Myoglobin in the urine may cause red-brown urine  Can progress to renal failure – tubular necrosis due to myoglobinuria  Potassium leakage from myocytes can cause cardiac arrythmia and even cardiac arrest! (Hyperklemia)
65
What is the energy requirement dependent on?
The energy requirement depends on the duration of activity and the distance traveled
66
What is milk fever? Who is most affected by it?
Older cows : bone and gut less responsive to pth and calcitriol than heifers. Peripartuant hypocalcemia occurs in 3 progressive stages, and can occur in both dairy and beef cattle.
67
What is the treatment of hypocalcemia? How can it be prevented?
- Calcium salts: usually in form of calcium borogluconate, iv slowly ( Rapid iv administration can result in cardiac arrest (stone heart syndrome). Therefore ascult while administering, if heartrate decreases below 60 bpm or you hear severe arrhythmia then stop administration for 20-30 seconds - pad areas, likely to fall and can become injured Prevention: Method 1: 1 month prior to calving, decrease Ca2+ so they could gear up PTH and Vitamin D3 homeostasis early on (this will prevent them from being "blindsided" by drop in calcium). Increasing calcium in feed will have opposite effect and induce milk fever. Method 2: Feed anionic salts for 2 weeks postpartum- inducing mild metabolic acidosis. This will aid calcium absorption in the gut, makes mineral more labile and improves renal activity of 1-alpha hydroxylase ( which activates vitamin D3) Risks: Can cause bone mineral liability, expensive, and may not work.
68
What is one of the main expenses in pork/ pig production? What is the amino acid that is limiting in pig diets?
- Feed • Lysine, is an essential amino acid that is expensive and is usually the limiting amino acid in pig diet
69
What are energy feeds?
- grains/ concentrates - oils and fats
70
What is magnesium an important cofactor for? What does it compete with?
- Cofactor for acetylcholinesterase, the ECF enzyme that cleaves Ach and terminates the stimulatory signal. - Cofactor for release of PTH from parathyroid gland. - Hypomagnesimia ( low mg2+ in ECF) may result in impaired PTH release. - Competes with calcium ( both are 2+ cations) and inhibits its stimulatory activity.
71
What is calcitonin? What does it do?
- Released from thyroid C cells in response of excessively high Ca2+ - Promotes deposition of calcium, into bone - Promotes calcium loss in kidneys - Effect: decreases CA2+ in the ECF
72
What are the signs of vitamin A toxicity in cats? What diet has affected cats been reported to eat?
• Reported in cats fed large amounts of beef liver – skeletal malformation – Fetal malformation – Liver failure – Kidney failure – Spontaneous bleeding
73
What is forage?
• FORAGE: • GRASS: INCLUDES GRAIN CROPS, TURF GRASS, BAMBOO • LEGUMES: ASSOCIATED BACTERIA ARE ABLE TO FIX NITROGEN (N2) INTO THE SOIL, THEN NH3 IS ABSORBED INTO THE PLANT AND CAN BE USED AS A SUBSTRATE FOR PROTEIN AND OTHER NITROGENOUS COMPOUNDS
74
What can grow in stagnant water? What can this lead to?
Stagnant water can grow blue green algae Could leaad to liver necrosis, tremors, diarrhea and even death. Hepatotoxicity
75
What are some examples of diseases seen in Dalmatians?
Dalmatian- urate urolithiasis
76
What questions should you ask a manufacturer when determining diets for patients?
1. Do you employ a boarded nutritionist or a PhD nutritionist? 2. Who formulates the diet? 3. Do you perform AAFCO feeding trials? 4. Do you analyze the finished product? If so, what does the analysis include? 5. What product research has been conducted?
77
What is the definition of these terms? - As Fed - Dry Matter - Crude Protein - Crude fat
- As Fed- percentage of nutrients including water • Dry Matter- percentage of nutrients without water • Crude protein- chemical analysis of the food which measures the approximate amount of protein in food by measuring the nitrogen content • Crude Fat- based on the solubility of lipids in non- polar organic solvents (ether extraction or acid hydrolysis)
78
What are types of analyses on pet food?
* Guaranteed analysis: * Min is provided for crude protein, fat (more expensive, more important) * Max is provided for fiber, moisture and sometimes ash (dont provide energy) * Carbohydrate content is then calculated by subtracting these 5 measured nutrients from 100% * Typical analysis: * Actual average nutrient content over multiple analyses * Averages are reported for crude protein, crude fat, moisture, fiber, ash * Dry matter: * similar to typical analysis- but without the moisture content
79
What is laminitis?
 Laminitis results from disruption of blood flow to the laminae  These laminae structures within the foot secure the coffin bone to the hoof wall  Inflammation often permanently weakens the laminae and interferes with the wall/bone bond  In severe cases, the bone and the hoof wall can separate
80
What can occur when there is excess phophorus or oxalates in certain grasses? Where is calcium absorbed?
- Can bind calcium and can have implications on skeletal health in growing foals and mares. - Calcium is mostly absorbed in the small intestines whereas phosphorus is mostly absorbed in the large intestines
81
What is Zinc a cofactor for? What can occur with Zinc excess? Zinc Deficiency?
• A cofactor to many enzymes including SOD therefore an antioxidant • Zinc excess is uncommon, but zinc can interfere with copper absorption • Zinc deficiency • Parakeratosis in the lower limbs • Decreased food intake
82
What is a horses normal diet composition?
~ 80 % energy - 8-14.4 % protien - 2-3 % minerals ~ 1% vitamins
83
What is the body fat percentage for ideal body condition for a dog?
BCS of 4 is 15-19% bodyfat anything above or below is not ideal
84
What are idea traits for a GILT at service?
220-240 days old = 31-34 weeks 135-150 kg wt P2 Fat depth = 18 mm 2nd or 3rd heat Target is feeing to develop the gilt and the progeny
85
How can you prevent ketosis in ruminants?
* Prevention is key. * Monitor high risk patients and make sure high risk are getting supportive measures for prevention. * Cows feel fuller during pregnancy so they eat less and will also have increased nutritional needs due to lactation status, so making sure they are on a diet that is calorically and nutritionally dense for their needs are essential.
86
What makes fat so important? When is it most important? What happen if there is an excess of fat?
• Provides a concentrated source of energy • Important especially in submaximal exercise • High fat: – overloads the gut lymphatics – Increase bile secretion – Slowed gastric emptying time – Increased pancreatic stimulation
87
What can occur with vitamin K deficiency? What can occur with vitamin K excess?
• Deficiency – Increased Clotting Time – Hemorrhage – All fish diet fed to cats need to be supplemented with vitamin K • Excess – No known complications
88
When could you see mold and spoilage with haylage/ silage? What are the concerns with certain molds? What bacteria can grow in spoiled pockets? What can they cause?
* MOLD AND SPOILAGE TYPICALLY OCCUR IN AREAS WHERE THE PACKING IS LESS TIGHT OR WHERE AIR/RAIN OR GROUNDWATER CAN ENTER * CERTAIN MOLDS CAN DEVELOP MYCOTOXINS THAT CAN BE DETERMINANTAL TO ANIMALS * SOME BACTERIA SUCH AS LISTERIA CAN GROW IN SPOILED POCKETS AND CAUSE ENCEPHALITIS AND ABORTION IN LIVESTOCK
89
Which is higher in these different components of feed? What does it provide to the diet? - Soy bean meal - Soy bean hulls - Wheat bran - Animal Fat - Vegetable oil
- Soy bean meal: protein source- higher digestible energy vs. net energy - Soy bean hulls: fiber - higher digestible energy vs. net energy. - Wheat bran: fiber- higher digestible energy vs. net energy. (more) - Animal Fat : fat - higher net energy vs. digestible energy. - Vegetable oil: fat - higher net energy vs. digestible energy. Fat digestion is more efficient with more heat conservation but the other products are required to have a balanced diet.
90
How do feeds affect blood glucose and insulin in the horse?
Glycemic index: the plasma/blood glucose response to ingestion of a measured amount of feed  The higher glycemic response typically produces a higher insulin response  Corn, oat, and barley all result in increase in blood glucose (BG) within 15 minutes - The glycemic index of hull-less oats is higher with a more rapid increase in BG (higher digestibility)  Barley is of low glycemic index  Pelleting and extrusion tend to reduce the glycemic index  Grass hay has a higher index than legume hay
91
What happens when energy requirements are not met? What happens when intake is low? When glucose is low?
- more impactful when this occurs during lactation - Energy requirements \> energy intake = negative energy balance • When intake is low, insulin is decreased and glucagon is increased ( increases gluconeogenesis), When glucose is in short supply, fats/ triglycerides are used as substitutes since lipids are "energy dense"
92
What occurs with the formation of ketone bodies?
- Ketones can be normal in moderate amounts when energy requirements are high (i.e lactation, ewes or does with large brood in last trimester) * Ketones remove unstable Acetyl CoA. * Ketones can be found and be normal, but excessive ketones can cause ketosis/ ketoacidosis. * Presentations of neurological signs, decreased appetite, pica, ect. * Can occur in severe chronic negative energy balance.
93
What is the limiting amino acid in swine diets?
Lysine is the limiting amino acid in most swine diets
94
How much colostrum must a piglet consume for adequate immunity? What percentage of piglets have not received colostrum? What occurs with smaller piglets and the amount of colostrum received?
200 ml 72% For every 100 g decrease in birth weight there is a reduction of 30 grams of colostrum intake ( too weak to get to teat, bullied out of way)
95
What can occur when you have high phosphorus and low calcium? What about too high of phosphorus? Where does phosphorus excretion occur?
• Can compete with calcium and reduce bone absorption. Low Ca++ and High Phosphorus in blood triggers chronically elevated PTH. Can cause bone resorption and condition called rubber jaw. • Ruminants on high grain diets may develop phosphate based urinary calculi if urine becomes highly concentrated ( i.e struvite ( magnesium ammonium phosphate). Disease termed urolithiasis. In ruminants: Phosphorus is usually excreted in the saliva and gi tract. - Saliva : supplies rumen bacteria with P source for ATP - Allows phosphorus recycling from blood into gut, minimizing urinary losses.
96
What are the essential amino acids?
Essential amino acids: arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, taurine
97
What can be seen in patients who are near soil with high molybdenum content?
It inteferes with copper absorption and can cause copper deficiency
98
What is important about the calcium content of grass hay and legume hay and how does it affect lactating mares?
• Grass hay is lower in calcium so may need to supplement • Legume hay has enough calcium, but may need to supplement phosphorus
99
What is the time frame in commercial facilities for each of the following: - Weaning - Gestation - Lactation - Growing / Finishing
- Weaning: 4+ 4 weeks ( 8 total) - Gestation: 114 days - Lactation: 21-28 days - Growing / Finishing : 10-12 weeks
100
What physiologic changes occur with aging?
- Skin and coat - Behavior/ cognition - Musculoskeletal system - Senses and metabolic flexibility - Digestive function Immune function
101
What is the issue with measuring via cup for pet food? What is the best recommendation?
• Inaccuracy was noted in the amount of food measured out (ranging from an 18% under‐estimate to an 80% over‐estimate) - USE A FOOD SCALE
102
What can prevent severe signs of hyperammonaemia? What does it not do?
Citrullin supplementation may prevent the severe signs of hyperammonaemia but do not sustain normal growth
103
What is the recommended ratio of Ca to phosphorus in mature horses? What impacts absorption of the other more?
* Excess phosphorus impacts calcium absorption more than the other way around * The recommended ratio (Ca:P) is 1:1 -5:1 in the mature horse
104
What is an indication of severe muscle loss?
The ability to feel the entire transverse process of the spine = poor muscling
105
What do dogs running for more than 30 minutes need?
Much more protein in their diet. Protein supports muscle mass.
106
What are the objectives on commercial production for sows/gilt? Piglet/weaning?Growing/ finishing pig? Will they all occur in the same location?
Sow/ GILT: Maximum # of piglets/ year Piglet/ Weaning: Minimize mortality and optimize health Growing-finishing pigs- maximum growth
107
How much water does suckling sows need? What should the flow rate of drinkers be? What are the differences in water needs from dry fed sows and wet fed sows?
* Sows require +20 litres per day * Drinkers should have flow rate of 2 litres per minute * Dry fed sows: give 4-5 litres via tap or hose morning and evening * Wet fed sows: give mix with 3-3.5 litres water per kg feed, plus additional water in first 7-10 days lactation
108
Can cats eat dog food exclusively?
No but dogs can eat cat food.
109
What are sources of the following for swine: - Energy (Carbohydrates/ Fats) - Proteins (Lys, met) - Minerals/vitamins
- Energy (Carbohydrates/ Fats): cereals, oils, fats - Proteins (Lys, met) - soy, linseed, pea, faba - Minerals/vitamins: ??????
110
What is important about the pH of where the haylage/ silage is stored?
Low pH prevents growth of mold and bacteria.
111
What is pregnancy toxemia? What is the gestation period of small ruminants? What is the correlation between number of embryos and metabolic strain?
- Another disease associated with chronic negative energy balance. Occurs in does and ewes in pregnancies with multiple offspring. Gestation in small ruminants last 142-150 days. Most embryonic development and growth takes place in the last trimester. More embryos -\> Higher metabolic strain
112
What can affect the hair color in cats?
• Tyrosine is a precursor for melanin. Lighter brown cats may be tyrosine levels lacking, supplementation should increase coat color. • The requirement for growth is much lower than the requirement for dark hair color
113
What can be the outcome a sporting dog without enough protein?
High protein is required for the prevention of ‘sports anemia
114
What can occur of feeding and exercise occur too close together? How can this be prevented ( or fixed)?
• Feeding + activity = GDV? – Most army dogs have had prophylactic gastropexy
115
What is 2 things should you look at to evaluate the condition of the patient during physical exam?
- BCS - MCS OR MMI
116
Why is thiamin important?
- Thiamin is important for the conversion of pyruvate to acetyl COA. - Thiamin deficiency can cause type B lactic acidosis since pyruvate cannot be converted into acetyl COA. Thiamin is also a cofactor for enzyme transketolase. This is a way thiamin levels are monitored, by looking at these levels. - Thiamin deficiency can also cause neurologic clinical signs. Since neurologic tissues have high energy requirements, so thiamin deficiency can result in neurologic signs.
117
What is a veterinary therapeutic diet? What is important to note about these diets?
- Veterinary therapeutic diets may have an indication to be fed intermittently as they may be technically not complete and balanced • Veterinary diets have specific indications and are typically named so that most owners would not immediately know what the indication is • These diets require a prescription • There are diets for multiple indications • Each company would have nutritional information in a product guide that would provide caloric density, caloric distribution (pro/fat/CHO), and nutrient (g) /1000 kcal
118
What is the term for poor energy intake? What can it lead to?
Starvation = poor energy intake Can lead to: - Fat catabolism - Catbohydrate store depletion - Once fat is depleted- protien catabolism.
119
Why do dogs that engage in short duration supra-maximal exercise not need as much protein?
– Glycogen stores do not get depleted and protein is not required to rebuild it
120
What is the water soluble vitamins? Which is the most important to remember? Why?
Vitamin B 1. Thiamin 2. Riboflavin 3. Niacin 4. Pyridoxine 5. Panthothenic Acid 6. Biotin 7. Folic Acid 8. Cobalamin 9. Choline (and vitamin C) Thiamin is most important, we see recalls due to thiamine deficiency.
121
What are clinical signs of iron deficiency?
Anemia Clinical Signs: • Pale white colour • Breathlessness • Jaundice • Scour (white) at about 3 weeks old • Reduction in growth rate = lower weaning weigh
122
How can you determine body weight of horses?
* Bodyweight can be measured on walk-in scales or estimated: * Lb Bodyweight= Heart girth (in)2 X Length (in) /330 * Kg Bodyweight= Heart girth (cm)2 X Length (cm)/11800 * Heart girth – measured behind elbows at expiration * Length- point of the shoulder to tuber ischii
123
What can be helpful to give to starved horses in terms of diet quality and composition?
• Could be helpful to provide a higher protein diet (similar to growth) unless contraindicated by concurrent disease • Make sure diet provides vitamins and minerals as needed • Watch for food aversion, difficulty in prehension or chewing
124
Is tyrosine an essential amino acid?
Tyrosine is not an essential amino acid in cats (although there is a requirement for phenylalanine+ tyrosine)
125
What percentage of extracellular calcium in the blood is ionized? When is more calcium bound to albumin? What will this cause? Can these cause any clinical signs? In ruminants, what do you normally see concurrently and why?
* More calcium bound to albumin during alkalosis, resulting in slightly lower Ca++ in the blood and ECF * Alkalosis can cause signs of hypocalcemia. * In ruminants normally occurs with diseases that impair abomasal emptying since hcl is trapped in abomasum and forestomachs, metabolic alkalosis.
126
What are other things that can decrease magnesium absorption from diet?
* GI tract absorption of Magnesium is generally inefficient. * High nitrogen (protein) as well as high dietary K+ will reduce magnesium absorption from the rumen since their will be a change in the electrical gradient. * Rapidly growing grasses have a lot of nitrogen and potassium.
127
What does magnesium metabolism adhere to? How likely is dietary deficiency reported? What else can cause deficiency?
- Closely adheres to calcium and phosphorus. - Dietary deficiency is uncommon, high P may reduce absorption as well as hypomagnesemic tetany.
128
What is Equine Metabolic Syndrome? What horses are most affected? What is your hallmark sign?
 Equine metabolic syndrome (EMS) is a characteristic collection of clinical signs and clinicopathologic changes in equids that places them at high risk for developing laminitis  Insulin dysregulation, the abnormal insulin response to oral or IV glucose is the hallmark of EMS  Most affected horses are obese, but insulin dysregulation can occur in thinner animals as well  increased regional adiposity in the neck and tailhead regions is typical Hallmark sign: Hyperinsulinemia with normal blood glucose concentrations (insulin resistance) is the hallmark finding.
129
What are the top 10 reasons for toy dogs to visit the veterinarian?
1. Vaccination / deworming 2. Health check 3. Skin & coat 4. Ear / Eye / Nose 5. Dental 6.Vomiting Diarrhea 7. Illness recheck 8. Lethargic 9. Lameness 10. Behaviour - Less commonly overweight
130
What are the nutritional guidelines for the senior pet?
- There are no specified guidelines for senior pets - Commercial senior diets vary in their nutritional content - It is important to feed for the life stage
131
What are the effects of high dietary calcium in great dane puppies?
- Great dane puppies developed abnormal both growth when the diet contained 3.3% calcium compared with diets with 1.1 % calcium - Miniature poodle puppies tolerated calcium intake between 0.33% and 3.3%
132
What is a horses daily water requirement?
Variable due to age, activity, physiologic state, temp Typically = kcal requirement. 0.3-0.8 gallons/100 lb/ day or 25-70 ml/kg/day
133
What are water needs of cats?
- Cats are thought to originate from the African Wild Cat, a desert dweller • Cats tend to drink less than dogs
134
What is important about magnesium in relation to its regulation? What are sources of magnesium in diets?
- Doesnt have specific hormones to regulate it - Doesnt mobilize bone mineral release. Mg absorption from gi tract is only regulatory mechanism for ECF. Animal must ingest from diet. Magnesium Sources: - Variety of plants, (legumes better than grasses) and nuts. - Animal tissues and liver are sources of mg ( for carnivores)
135
Is taurine an essential amino acid? What is the function of taurine? What is the conditional situation taurine is essential to dogs?
• Taurine is not considered essential in mammals with the exceptions of cats and human infants • It is considered conditionally essential in dogs • Taurine is conjugated to bile acids, similar to glycine – Dogs and cats use taurine rather than glycine; whereas other mammals may use either In addition, taurine acts as an antioxidant and deficiency results in increased oxidative damage – Taurine deficiencies leading to DCM have been described in Newfoundlands and in cocker spaniels
136
What is the treatment of colic? what are the different types of colic? What can you do to prevent colic?
Treatment:  Soak food- divide to 3-4 meals  Provide soluble fiber- beet pulp  Wheat bran  Psyllium  Linseed  Provide salt blocks to avoid pica  Flunixin meglumine- reduces the cellular production of prostaglandins but can also mask signs  Gas colic- in large intestines, can palpate  The result of excessive fermentation and gas production  Can be the result of high energy feeds such as grain, lush forage  Sand colic-  Large intestines- hard to palpate  Suspect according to environment and sand in feces  Prevention:  Access to water  Dental health  Avoid excess grain/high energy forage  Slow transition to diet change  Avoid feeding when horses are ‘hot’ after exercise  Encourage owners to become educated on fed quality, dental care, vital signs and recognizing early signs of distress
137
What are protien requirements of horses dependent on?
* age * Physiological state * Activity * Feed intake * Digestibility
138
What facilitates calcium absorption? What dietary factors can affect calcium absorption?
Activated Vitamin D, and Parathyroid Hormone. - Phosphorus and magnesium content - High dietary zinc (many times due to formulation error) - Oxalates (can be posionous)
139
What are the types of hay? Is hay in a bale of a single species?
• HAY CAN BE COMPRISED OF A SINGLE SPECIES, OR A COMBINATION OF SEVERAL SPECIES • CAN BE FROM FORAGE THAT IS NATIVE OR CULTIVATED • MOST HAYS ARE EITHER GRASSES (TIMOTHY GRASS HAY, ORCHARD GRASS HAY), OR LEGUME HAY (ALFALFA HAY)
140
What is the difference of energy requirements in donkeys than in horses? What occur if donkeys are fed with horses?
• Energy requirements are also lower than horses (50-70% of a similar size horse) • Can become obese and develop hyperlipidemia, laminitis and other metabolic complications if fed with horses
141
What are AAFCO protocols?
• Each life stage has its own protocol. Life stages are the same for both dogs and cats and are defined as: • Adult Maintenance • Growth • Gestation/ Lactation • All Life Stages • A minimum of eight healthy adult dogs at least one year of age and of optimal body weight • Test is 26 weeks at least • BW, food intake, Hemoglobin, packed cell volume, serum alkaline phosphatase and serum albumin shall be measured and recorded at the end of the test
142
What is the increase in protien requirements in the lactating horse? How can you balance that diet, and how much grain protien is needed to give the correct amount of protien?
* Protein requirements increase to 13% * Can be balanced with a combination of legume hay or legume grass * If legume hay is provided, grain protein can be 12% * If grass hay is provided, grain protein needs to be at least 16%
143
What is the process of gluconeogenesis in ruminants?
• Non esterfied Fatty acids sent to liver to become Triglycerides ( which then becomes VLDL), Ketone bodies ( exportable energy source used by extra hepatic tissues) or for fuel for hepatic metabolism to make energy.
144
What can occur with hay that is too rich?
HAY THAT IS TOO RICH CAN CAUSE DIGESTIVE PROBLEMS • BLOAT • ENTEROTOXAEMIA • LAMINITIS • PULMONARY EDEMA (CATTLE)
145
What is the target peak feed intake in kg per day for sows with their first litter, and with sows that have had multiple litters? How long should she be fed to appetite?
First litter: 6.5 kg Sow (multiple litters): 8 Kg - feed to appetite from day 4-5 until weaning
146
What occurs when both PTH and Calcitonin is high?
When both PTH and calcitonin are high, they have competing effects on the bone - PTH stimulates resorption while calcitonin stimulates bone remodeling • The result is abnormal bone growth
147
What does it mean if a bale of hay has more leaf content? What does the color of the hay indicate?
* FROM APPEARANCE: LEAF CONTENT (MORE PROTEIN, STARCH) * COLOR- GREEN=GOOD; BROWN= MOLD, SUN EXPOSURE, WET
148
What is Non protien nitrogen? Is it a good source of Nitrogen in the horse?
NPN such as urea is not useful in the horse as it will be absorbed in the small intestines and excreted as urea in the urine • This is unlike foregut fermenters where the bacteria can utilize the nitrogen BEFORE it is absorbed in the SI • If the feed contains urea, it should be subtracted from the crude protein analysis (which is nitrogen analysis) • NPN is less toxic in horses than foregut fermenters
149
What is colic? What causes colic? What are the signs of colic?
Colic is a general name for abdominal pain - Many possible causes - If colic is prevalent- check diet, dentition, parasite control - Impaction colic- usually in the large intestines, often can be palpated - Can be caused by: Indigestible food, Sand, pica, poor hydration  Signs of colic include:  Pawing  Rolling  Bloating  Sweating  Distress  Uneasiness  Loss of interest in food and water  Peculiar postures (sitting, stretching)  Absence of gut sounds
150
When does gut closure take place in piglets, preventing antibody absorption? What time frame is the most critical?
Gut closure in piglet can take place as early as 24 hours after birth * Piglet no longer capable of absorbing antibodies from gut * Piglet must consume sufficient antibodies within first 24 hours or earlier * Colostrum intake in first 6 hours is critical – the earlier the better
151
What is important to note about hypercalcemia in puppies? At what age can puppies begin to regulate their calcium levels?
Puppies of different breeds have different sensitivities to calcium excess • Until the age of 6 months, puppies do not regulate calcium absorption
152
What is the treatments for ketosis?
Treatment * Treat underlying disease, or feeding high quality carbohydrate meals. * Add molasses in the water, orogastric tube feeding. - Transfaunation: If you have a fistulated cows, you can transfer rumen fluid from healthy cow to sick cow, can be administered via orogastric tube. - Adminsiter propylene glycol: metabolized by the liver to propionate. If animal has liver failure no point to give since it wont be metabolized. Overdose can cause diarrhea, ataxia, coma ect. • Glucose IV (decreases ketone formation) • Corticosteroids: enhances gluconeogenesis, reduce milk production. improve how animal feels. ◦ Negatives: Can induce abortion if pregnant. Stimulates hormone sensitive lipase, which increases FFA production which is not ideal in these patients. - Glucose IV + insulin SC: can be given together to reduce lipolysis -\> you will see decrease of phosphorus, magnesusm, and potassium. - Give B vitamins : likely low, synthesized by rumen microbiota, niacin and choline (can help form lipoprotiens and transport fat from the liver in fattyliver disease)
153
What are cats in terms of the type of animal they are?
Cats are obligate carnivores (however, this does not mean they cannot eat vegetables too!)
154
What are sources of vitamin E? What can happen to Vitamin E in pet foods if stored improperly?
• Sources – Wheat Germ – Corn Oil – Soybean Oil - The Vitamin E in pet foods can be oxidized if not stored properly
155
What can cause laminitis? What are the clinical signs?
Etiology:  Can be caused by certain toxins such as bacterial toxins  This can be the result of GI dysbiosis, nutritional factors, or an infection Excessive carbohydrate intake- incidental grain overload  Grains, green pasture  Gut microbial shift: not all carbohydrate will be digested in the small intestines, fermentation in the large intestines causes acidosis  bacterial die-off and release of endotoxins  Endotoxemia can cause and increase in TPR, colic (within 12-16 hours) laminitis (within 24 hours)  Clinical signs:  Lameness  Pain  Change in the hoof structure in chronic disease  Can be fatal
156
What is chronic kidney disease? What causes it? Is it common in horses? And what diet is recommended?
Chronic kidney disease is relatively uncommon in horses  Common causes: high blood pressure, coagulopathies, pyelonephritis and tumors  Renal disease is typically progressive  Unfortunately, no clear diet recommendations- avoid high protein (legumes for example)  Protein \< 8%  Carbohydrate based diet  Adequate hydration
157
What can you tell by the product name in terms of quantity of ingredients?
• The "95%" rule: applies to products consisting primarily of very few ingredients. Simple names, such as "Beef for Dogs" or "Tuna Cat Food”. • The “25%” rule : If the named ingredients comprise at least 25% of the product but less than 95%, the name must include a qualifying descriptive term, such as “Dinner”. • At least 95% of the product must be the named ingredient (aside of water for processing) • “Chicken 'n Liver Dog Food," the two named ingredients together must comprise 95% - The "3%" or "with“: The named ingredient (‘with cheese’) is required at least 3% of the product • Flavor: a specific percentage is not required, but a product must contain an amount sufficient to be able to be detected
158
What are the types of roughage?
Forage Straw Silage/haylage seed hulls
159
What are the different terms for hay cuttings?
• CUTTING REFERS TO THE ORDER IN WHICH THE HAY HARVEST WAS CUT (BEGINNING OF SEASON VS. LATE IN SEASON) • 1ST CUTTING: FIRST HARVEST, VARIABLE MATURITY (SOME PLANTS ARE IN EARLY GROWTH, SOME ARE MATURE); LESS DIGESTIBLE, LOWER NUTRITIONAL VALUE • 2ND, 3RD CUTTING: UNIFORM GROWTH, GREATER WATER PENETRATION AND WARMER WEATHER; HIGHER NUTRITIONAL VALUE AND DIGESTIBILITY
160
What environmental factors are important to consider when feeding?
• Quality of the pet's surroundings – Husbandry – Multiple Pets – Environmental Stimulation
161
What is calcium important for?
- Found in every cell - Bone is major storage pool for calcium of hydroxyapatite - Component in milk (high requirement during lactation) - Important muscle activity ( actin- myosin coupling) - Influx in cells may trigger cell death (both in normal and pathologic processes) - Calcium is required in hormone/ neurotransmitter release. - Dampen neuronal excitation potential that requires sodium channel activity.
162
What is the effective environmental temperature in terms of pig rearing?
* Air temperature in pen and the combined effects of: * Air speed * Floor type * Air to wall temperature difference * Group size (group vs individual pig)
163
What are some examples of diseases seen in Miniature Schnauzer?
Miniature Schnauzer- calcium oxalate urolithaisis, hyperlipidemia, pancreatitis
164
What are the causes of post weaning diarrhea?
- Loss of maternal antibodies - Move to new environment - Stressful (mixing/ moving) - Possible high infectious - Food ( change of flora, composition, too much, too little)
165
When would most foals begin to wean? When would you start introducing creep feed?
Most foals would wean between 3 and 7 months. You would start to introduce creep feed at 1-3 months.
166
What is roughage?
high fiber foods
167
What is important about feeding a stallion? What would need to be avoided? When may you need to increase the concentrate?
Feed to maintain an ideal BCS • May need to increase amount of concentrate in breeding (showing off for female) • Avoid obesity- poor fertility (poor sperm quality when obese)
168
What is hypophosphatemia? What can occur/clinical signs? What triggers it? What is the treatment?
• Low phosphorus in ECF. - relatively uncommon, can occur with milk fever. Clinical presentation: usually alert but show weakness/ and inability to stand. Cows can attempt to rise on multiple occasions pushing part way up on legs and moving around pen on abdomen. "termed creeper cows" Trigger: Lactation triggers heavy ca2+ loss in milk, triggers pth secretion, pth moves alot of phosphate into urine, and persistent weakness is likely due to ATP depletion from muscle cells. Treatment: Blood Samples: Note hemolysis increases blood phosphorus because it leaks from ruptured RBC - IV Monosodium phosphate. Cannot mix Ca++ containing soluion. CaPO4 aggregrates and will precipitate. - Phos supplements - Offer phosphorus rich grains - Consider checking vitamin D status of diet
169
What is the pathogenesis of hyperlipidemia? Is it different than in other species?
 The pathogenesis is similar with other species:  Free fatty acids are mobilized to provide energy at a rate that exceed their metabolism (fatty acid oxidation or formation of ketone bodies)  Lipids are re-esterified to triglycerides  May accumulate in the liver where they are metabolized to energy  The fat accumulates in hepatocytes and can also cause clots/emboli in blood vessels
170
What is the issue with acute arginine deficiency? Why?
* Acute deficiency in most essential amino acids may lead to growth impairment and reduced food intake * Arginine deletion may cause death in a single meal! This is because it allows for ammonia to build up in the system, and this can cause death
171
What are critical measures for reproductive success? When are demands highest for sows?
• The body condition and back fat of the gilt are critical measures for reproductive success and therefore longevity • On the other hand, excessive BCS during gestation can make parturition more difficult • Demands are the highest during lactation
172
What are the 3 ketones?
- acetoacetate, betahydroxybutyrate, acetone
173
What is the quantity of water a performance horse will typically drink, and what can affect that?
* Water: 30-40 L per day (depends on temperature and activity) * Higher requirement if main diet is dry hay rather than pasture/forage * Water needs to be clean * Restrict access is horse is hot/water too cold ( to prevent colic) * 2-3 L every 15-30 minutes
174
If gross energy = 100 % where is the energy lost?
Feces - 20% Digestible (after removing feces) - energy 80% Urine and gas - 4% Metabolizable ( after removing urine and gas) - 76% Heat increment- 18% ( can go up to 38% if conditions are optimal but is costly for farmer) Net energy (after heat increment removed) - 58% NE retained: 38% (for meat) NE maintenance: 20%
175
Do cats taste sweet flavor? What else is important for cats diets?
• Cats don’t have a taste receptor for sweet flavor • Cats need a higher protein and fat diet than dogs
176
What is zinc deficiency? What can it cause in puppies? Northern breeds?
Zinc deficiency: Puppies- poor growth, skin lesions Northern breeds- genetic defect resulting in interference with zinc absorption, dermal lesions
177
What is the path of objects after being swallowed?
Feed/water, and saliva are delivered to the reticulorumen through the esophageal orafice. Foreign objects like rocks and nails go to the reticulum. Food is broken down into smaller pieces, that then is pushed into the retiuculum through the reticulo- omasal orifice into the omasum. It will eventually make it into the rumen or the fermentation vat.
178
What can occur if foals are exposed to excess zinc?
In foals -\> excess may cause joint disease
179
What can cause monday morning disease? What other animals can it be seen in?
It is possible that horses on a high fat diet and low antioxidant intake are at higher risk of exercise-related oxidative damage - Also reported in sled dogs/sporting dogs and wildlife during capture and transport, and in humans - Can also result for other extensive muscle damage such as trauma, burns, snake bites, electrocution, heat stroke - Other causes: - Vitamin E/ selenium deficiency - Electrolyte imbalance (sweat, heat) - Underlying disease (fever) - Polysaccharide storage myopathy-glycogen storage disorder - Quarter horses - Warmblood - Draft horses
180
What are the legal requirements in the EU in regards to water access?
• Suckling sows, and piglets over 2 weeks of age must have permanent access to sufficient quantity of fresh water
181
What is phosphorus? Where can you find it? What is it used for? What can it compete with?
It is a component of bone mineral and tooth enamel. 85% of total body P in hydroxyapatite Phospholipids in cell and cellular organelle membranes. Energy metabolism: ATP Sources: - Grains - Wheat bran - Supplements - Grasses are low in Phosphorus Phosphorus competes with calcium and can reduce its absorption.
182
What is silage? What is haylage?
SILAGE: CEREAL CROP (FOR EXAMPLE: CORN SILAGE) THAT IS CHOPPED AND FERMENTED PRIOR TO BEING FED. • USUALLY THE ENTIRE PLANT IS INCLUDED: STEMS, LEAVES AND GRAIN • 65%-70% MOISTURE AND 30-35% DRY MATTER • HAYLAGE: IS MADE FROM A NON-GRAIN FORAGE SUCH AS ALFALFA. • ALSO COMPRISES THE ENTIRE PLANT. • MOISTURE 40-50%
183
5 year old MC Labrador 50 lbs BCS of 4 out of 9, normal muscle mass. Calculate Hanks RER? What Life stage factor would you use? What is the MER for Hank?
RER: 751 Life stage: Can use neutered factor or obese prone. Neutered: 1165 kcal/ day Obese prone: 874 kcal per day
184
Why must newborn piglets get colostrum?
To Provide: • Energy and other nutrients to avoid starvation • Liquid to prevent dehydration • Antibodies to protect against infections
185
What occurs in protien catabolism?
- Catabolism of liver protien - Decreased plasma protien (edema/ ascites) - Poor immunity, skin, respiratory and cardiac functions - Skeletal muscles spared as long as possible ( needs to be spared for fight or flight)
186
What other considerations are there for neglected horses?
Many neglected horses have endo and ectoparasites, dematophytes (fungal infections) other wounds.
187
What is included in a typical nutritional assesment of horses?
Full medical history * Housing/environment- inspect if possible * Reproductive history * Detailed diet history * What is being fed, how often, any supplementation * How is the feed offered * Feeding behavior
188
What should you look for in the critically ill horse before reinstating feeding schedule?
check for gastric reflux before feeding
189
What is found in the plasma normally of cats (and dogs)? Who is less sensitive to vitamin A toxicity?
• In cats (and dogs) retinyl esters may be found in the plasma normally • Cats are less sensitive to vitamin A toxicity (although not resistant)
190
What occurs in adult dogs when fed high dietary calcium? What was the result of the study?
Adult dogs are capable of regulating calcium balance, without adverse effects on health when fed a high calcium diet. Calcium excretion was proportional to calcium intake in adult dogs.
191
What are the goals of adult animals nutritionally?
– Appropriate energy and nutrients
192
What is in the cell contents of plants? cell wall? Intercellular cement?
Cell contents: - Sugar - Starch - Proteins - Vitamins - Most minerals Cell Wall: - Cellulose - Hemicellulose - Lignin Intercellular cement: - Pectin - Gums
193
What is the potential future for pet food labels?
- The Guaranteed analysis box may be replaced with a ‘Pet Nutrition Information’ box • This will have some similarities to the human food labels • Total dietary fiber will be reported as well as total carbohydrate • Values will be ‘typical’ instead of maximum and minimum
194
What is fiber? What does soluble fiber do? What occurs when there is an excess of fiber?
- Fiber is indigestible carbohydrate - Soluble fiber acts as a prebiotic and supports gut microbiota Excess fiber- – higher fecal volume – Water loss in feces
195
What are benefits of smooth weaning transitions?
Smooth weaning transition • Initiates digestive development • Improve weights • Improves weaning intakes
196
What is lipolysis? What is the enzyme that facilitates lipolysis? What is lypolyis promoted by?
- Lipolysis - process of breaking down lipids to glycerol and 3 free fatty acids (FFA) - HSL (hormone sensitive lipase) is enzyme that facilitates it - It is promoted by: Negative energy balance High glucagon and low insulin Stress -\> cortisol release Stress -\> epinephrine release
197
What is Rhabdomyolysis - Monday Morning Disease? What horses do you see it in? What is the result of this disease?
- Rhabdomyolysis is damage/destruction of muscles - Usually the result of extreme exercise and excretion - Especially in race-horses- Thoroughbred, standardbred, Arabian - Results in severe muscle damage that is extensive enough to have considerable metabolic implications
198
What is the 5th vital assessment?
Diet evaluation (Ask about gastro fxn, previous/ ongoing medical condition, medication, unconventional diet, snacks/treats/ table food, inappropriate feeding management, inadequate housing.
199
What are essential nutrients? What is complete feed? What is most livestock diets like?
* ESSENTIAL NUTRIENTS= NUTRIENTS THAT MUST BE PROVIDED FROM THE DIET TO SUPPORT HEALTH * COMPLETE FEED= FEED FORMULATED TO PROVIDE ALL THE ESSENTIAL NUTRIENTS FOR THE ANIMAL (EXCEPT WATER). * CAN BE FED AS A SOLE FOOD SOURCE (EXAMPLE: EXTRUDED DIETS FOR DOGS AND CATS THAT ARE COMPLETE AND BALANCED) * MOST LIVESTOCK DIETS ARE A MIXTURE OF INDIVIDUAL FEEDSTUFF, ALTHOUGH COMPLETE FEEDS ARE AVAILABLE TOO
200
What are the resting energy requirements for the following dogs: Racing Greyhounds Hunting dogs Sled dogs
Racing Grey hounds: 2 Hunting dogs: 3.4 Sled dogs: 15
201
What temperature is dangerous and considered overheating? What organs are most susceptible? What would increase the risk of overheating?
- Very high body temperature (\<104) can be dangerous • Intestines and kidneys (intestinal mucosa/ kidney damage) are susceptible • Dehydration increases the risk for overheating
202
What do dogs initially use as a source of glucose during submaximal energy? When does gluconeogenesis increase?
Dogs initially use glycogen as a source of glucose during submaximal exercise • Increase gluconeogenesis from protein after about 30 min (Wasserman et al. 1992)
203
What is important to note about back of the bag feeding guidelines?
• May over estimate what should be fed • Can be used as a quick guide to determine if nutrients will be met if restricting diet for weight management - ASCESS INDIVIDUAL PATIENTS NEEDS TO MAKE ADEQUATE RECOMMENDATIONS
204
What occurs with protien deficiency?
Usually accompanied by overall energy malnutrition • Weight loss • Poor skin/hair quality • Poor growth • Decreased lactation (mares) • Poor performance • Biochemistry: • Low BUN • Low albumin/TP • Edema possible
205
Insufficient water intake in horses will cause?
- Dehydration - Colic - Poor performance - Impaction
206
What is important does it take for dogs of different sizes to reach adult size?
Appears breed specific – Small dogs reach adult body size earlier (under 1 year to 1.5 years) – Large and giant dogs may continue skeletal development for over two years
207
What is NPN? Where is it useful? What is it used for? Where is it absorbed in other species?
NITROGEN-CONTAINING FEEDSTUFFS INCLUDE NOT ONLY PROTEINS BUT COMPOUNDS SUCH AS UREA, BIURET, AND AMMONIATED FORAGES • THESE ARE NOT USEFUL IN MONOGASTRIC OR HINDGUT FERMENTERS BUT ARE USEFUL IN FOREGUT FERMENTERS • THE MICROBES MAY UTILIZE THESE COMPOUNDS TO SYNTHESIZE PROTEIN WHICH CAN LATER BE ABSORBED • IN SPECIES OTHER THAN FOREGUT FERMENTERS, THE NPN IS ABSORBED IN THE SMALL INTESTINES AS IS, AND LATER EXCRETED IN THE URINE
208
What can occur with excessive vitamin A?
Excess – Skeletal Abnormalities (calcification around joint as example) – Hyperesthesia (very sensitive to touch and sensation) – Mucus membrane damage
209
What is important to keep an eye on in donkeys? What do pregnant or lactating Jennys need along with growing donkeys? What is the concern with feeding concentrates?
Dental health- important as they consume very high fiber food • Pregnant or lactating jenny (female donkey) and growing donkeys require supplementation with higher energy and protein feeds • Alfalfa • Beet pulp • Rice bran • Supplementation feed should be given in small amounts and mixed with straw • Avoid concentrates in donkeys- high risk for laminitis and colic
210
How do we compare foods according to the labels?
- Products differ in labeling • Ash and fiber don’t provide calories • Animals eat primarily to meet energy req
211
What is the procedure for iron injection?
- Collect litter in box/ creep area. - Roll skin over muscle, inject IM into neck muscle - Roll skin back and apply pressure to injection site. - Use 200 mg Iron dextran ( preferably in 1 ml) - Painful injection, expect response
212
What kind of stomachs do pigs have? What part of the GI tract is well developed? Where do they ferment soluble fiber? Where do they ferment insoluble fiber?
- Mono-gastric species - Well developed cecum - Fermentation for soluble fiber is in the small intestine (ileum) or in the cecum. - Fermentation for insoluble fiber largely occurs in the colon
213
What occurs with the amine groups in cats?
In cats – the amine groups removed are continuously metabolized to urea
214
What is a horses drinking behavior?
- Usually small volumes each time - 2-3 drinks per bout - Higher demands horses will drink more times, but normally not more drinks - If frequency is restricted, may increase drinks, volume is constant.
215
What can donkeys eat that is not advised in horses? Why?
* Able to feed on lignin-rich, low energy food- Slower GI transit allows increased fermentation * Evolved to survive in a semi-arid mountainous environment * Forager
216
What is important to look at in terms of hay quality?
• MORE LEAVES AND LESS STEMS, BRIGHTER GREEN COLOR= HIGHER QUALITY • ODOR: PLEASANT, NOT MOLDY • MOLDY BASEMENT SMELL: HAY WAS BALED TOO WET OR GOT WET IN STORAGE • WATER DAMAGE: DARKENED BROWN HAY, MOLD SPORES SEEN
217
What is the National Research Counsel recommended allowance? What is the National Research Counsel safe upper limit?
- NRC Recommended allowance- the amount of a nutrient in a diet formulated to support a given physiological state, based on the minimal requirement and where applicable includes a bioavailability factor • NRC Safe Upper Limit - maximal amount of a nutrient that has not been associated with adverse effects
218
What happens if sow is in poor BCS at the beginning of her next cycle?
Likely that will be the last time she can be bred
219
What are the protein requirements of working / running dogs?
Protein requirement tied to energy • Commercial diet protein digestibility 80-90%
220
What is oxalate poisoning? What does it cause?
High oxalate plants have potential to be posionous. Rumen can detoxify oxalates but is dependent on bacterial content and can be overwhelmed when large ammounts are ingested. - Forms insoluable salts that precipitate in the kidney causing kidney failure.
221
What is suggested feeding plan for EMS?
Slow steady weight loss After weight loss, previously obese horses will likely have lower energy requirements than their lean counterparts.  Exercise – moderate to allow gradual decrease in adiposity  Avoid overexcretion and rhabdomyolysis
222
What is the lab values that indicate rhabdomyolysis?
- Elevated serum creatine kinase - Elevated serum AST - Elevated serum potassium - Myoglobinuria
223
What is the treatment for hyperlipidemia?
 Mortality- high  Treat primary illness  If anorexic- feeding tube is indicated to reverse catabolic state  Insulin- can work with ponies – can stimulate peripheral lipoprotein lipases  Prevention is key!  Maintain an ideal BCS  Address disease and monitor intake  Provide high quality diet for mares during pregnancy and lactation
224
What is important about feeding during gestation-lactation?
- Maximize intake during lactation to produce enough milk for the piglets - Gestation: develop progeny enough avoiding excessive BCS at farrowing (restricted) that makes farrowing difficult
225
What are the 3 stages of milk fever clinical signs?
◦ Stage 1: standing, apprehensive, hypersensitive, tremors. This is loss of dampening on sodium channels. ◦ Stage 2: Loss of Ca2+ influx at motor end plate of the axon causes less acetyl choline to be released per action potential. Decreased calcium ECF. Cows recumbent and too weak to stand, head may be turned to back if too heavy to lift. ◦ Stage 3: Comatose. Death can occur from cardiac/ respiratory failure/ can also cause rumen regurgitation and cause aspiration pneumonia.
226
What occurs in VFA metabolism? What is acetic acid oxidixed for? What is propionic acid used for? What is Butyric acid used for?
VFA's absorbed across ruminal epitheleum to ruminal veins, portal vein and liver. Removal of VFA important to prevent rumen acidosis Acetic acid oxidized to generate ATP and used as source of acetyl COA for lipid synthesis Propionic acid -\> gluconeogenesis -Almost no glucose makes it to the small intestines for absorption. Butyric acid metabolized by rumen epithelium to ketone beta hydroxybutyric acid. Used for energy production.
227
How does Calcium dampen the neuronal excitation potential that requires sodium channel activity?
- Terminus of neuron, calcium enters the cell in response to action potential. - Calcium ion promotes fusion of vesicles containing acetylcholine with the membrane.
228
What are the goals of young animals nutritionally?
– Feeding for optimal growth – Avoid over feeding- obesity, orthopedic disease
229
What is Vitamin K important for? What factors is it required for?
Function • Clotting Cascade – Required for synthesis of: • prothrombin (Factor II) • Factor VII • Factor IX • Factor X
230
What are the functions of copper?
– Collagen/ elastin synthesis (dematuration) – Iron mobilization (deficiency-\> anemia) – Melatonin synthesis (reddening of black hair coat
231
What is important to remember about cats and their protein requirements?
Cats have higher protein requirements than dogs.
232
What is PTH released from? What do they do? What occurs in young animals? Older animals?
PTH released by chief cells of parathyroid in response to low ionized calcium. This acts to increase Ca2+ in ECF. - PTH promotes bone resorption to provide Ca2+. • Bones of younger animals (12-24 hours) responds more rapidly than older animals(24-48+ hours). • Reabsorption of calcium ion from the glomerular filtrate in the kidney. - Loss of phosphate ion in saliva and urine. - Transformation of inactive vitamin D to active vitamin D
233
What is Lignin? Is it digestible? What does a higher quantity of lignin mean for the food source? When will the plant have the highest quantity of lignin?
• SOME STRUCTURAL COMPONENTS OF THE PLANT CANNOT BE DIGESTED BY MAMMALS OR BY BACTERIA • LIGNIN IS A NON CARBOHYDRATE CARBON POLYMER • LIGNIN CONTENT INCREASES IN PLANTS AS THEY MATURE AND GROW • MORE LIGNIN= LOWER DIGESTIBILITY • LIGNIN MOLECULES ARE HIGH IN HYDROCARBONS- THIS IS WHAT MAKES DRY WOOD COMBUSTIBLE
234
In fermentation, what releases energy for microbial use? what gases are produced during fermentation?
* DISSIMILATION RELEASES ENERGY FOR MICROBIAL USE * GASSES (CO2, METHANE) ARE PRODUCED DURING FERMENTATION
235
What is straw? What is straw rich in?
* STEMS OF MATURE GRAIN PLANTS * THIS IS WHAT REMAINS WHEN THE GRAINS ARE REMOVED * EXAMPLES: OAT STRAW, WHEAT STRAW, BEAN STRAW • SINCE SEEDS ARE HARVESTED IN MATURITY (LARGEST SIZE), STEMS ARE THICK AND HIGH IN LIGNIN
236
What is the ideal BCS of a halter competition/ pleasure horse? What is their daily energy requirement? What about a race competition horse (3 day events)?
Halter Competition/ Pleasure Horse: 5-6 (1.2 x (DER for Rest)) Race Competition (3 day events): 4-5 (1.9 x(DER for Rest))
237
What is the function of vitamin D? What do they not have that changes their vitamin D absorption? What must they do instead?
• Function: Regulate Calcium and Phosphorus Metabolism - Low Concentrations of 7- dehydrocholesterol in skin so they cannot receive the Vitamin D from the sun. - They must get it from their food.
238
What are the essential fatty acids? How do horses get these fatty acids? What percent of fats are in their meals and when may it be preferable to highly digestable carbs?
• Essential fatty acids: linoleic acids and arachidonic acid • Horses can form these FA, so not necessary from the diet • Fats are 2-6% of the meal (DM) usually • Can be increased up to 10% (20% of the daily kcal) gradually with a palatable oil •Also add vitamin E • May be preferable to highly (Due to risk of oxidation) digestible carbohydrates when energy demands are high • Less risk of colic and laminitis
239
What is the purpose of saliva? What is the gas that makes up the majority of the ruminal gasses?
Saliva is used as a buffer Much of gas that fills rumen is methane
240
What are cats low in, in terms of glucose conversion? What has the same function and how is it different? What else are cats lacking when it comes to breaking down sugars?
Cats low in liver glucokinase- needed to convert glucose to glucose-6- phosphate – This system typically responds to a high sugar load - Hexokinase has the same function but lower capacity (lower Vmax) to handle high glucose load • Cats lack liver fructokinase- unable to utilize fructose or sucrose
241
How long is a food trial?
26 weeks
242
What can be causes of insufficient water intake?
- Broken equipment - Poor quality, dirty, unpalatable water - Water with high particle count \> 6500 mg/L is not palatable.
243
What relationship does vitamin E have with vitamin A? PUFA? Selenium?
• Interrelationship – Vitamin A • Vit E prevents oxidation of Vit A – Polyunsaturated Fatty Acids (PUFA) • Requirement for Vit E depends on the amount of PUFA’s in the diet . – Selenium • work together to prevent oxidation of cell membrane
244
What is an important BCS for gestation? What are common nutritional issues during this time? When is it important to increase food intake?
Maintain BCS of 5-6 • More issues with under nutrition rather than over nutrition • No increase in food intake necessary until last trimester (week 16) of pregnancy
245
What are the clinical signs of pregnancy toxemia in cattle? Pathophysiology? Treatment?
Clinical signs: - Illness ( poor doer) in last trimester - Poor appetite - Seperated from flock - Stargazing - Weakness Pathophysiology: Unrelenting glucose requirement from fetus, this can be fatal. Ketosis also usually occurs and ewes get ketoacidosis. Treatment: - Termination of pregnancy - Alternatively can try supportive care but likely wont work Supportive care : IV glucose, propylene glycol, transfaunation, highly digestible high carbohydrate food (even sugary cerals can be supplemental)
246
How do you calculate RER (in kcal)?
Exponential equation: (bodyweight in kg) 0.75 X 70 Linear equation for animals 5-95 pounds: 30 (bodyweight in kg) + 70
247
What is potassium important for? What is it dependent on?
Important for normal cardiac function, acid base balance, renal function, neural function. Dependent on activity and physiologic/ Pathologic state.
248
What are the stages of maturity of hay?
``` BUD STAGE (PRE BLOOM): HIGHEST NUTRIENT CONTENT • BLOOM: MORE MATURE, HIGH YIELD (BIOMASS), DECREASED DIGESTIBILITY VS. BUD STAGE • SEED PRODUCTION STAGE (GONE TO SEED): AGED, LESS DIGESTIBLE AND LESS NUTRITIOUS • DORMANT: LEAST DIGESTIBLE AND LEAST NUTRITIOUS (SOMETIMES BURNT TO FERTILIZE THE SOIL WITH MINERALS RATHER THAN USED FOR GRAZE) ```
249
What are clinical signs of hypothyroidism?
- dry coat - alopecia - impaired growth - decreased bone mineralization - Lethargy, inappetence. - Cold intolerance - Goiter (swelling of thyroid gland)
250
As pigs get older, what happens with amylase protease and lactase?
Lactase activity is highest in first few weeks but steadily declines. Amylase protease starts out low but increases quickly as time goes on
251
What is the long term complications of negative energy balance?
* Limited reserve muscle so it is not primary source of alternative energy. * Acetyl CoA is chemically unstable, so the body does not want excess of it since it can cause oxidative damage. - Glycogen reserves depleted quickly - Fat reserves are main source of energy. Oxaloacetate is limited and is depleted before all acetyl coa units are used up
252
what are the different energy requirement terms? What do they mean?
• Resting Energy Requirements (RER) – Energy required at maintenance state, moderate activity • Daily Energy Requirements (DER) – Includes: work, gestation, lactation and growth – Normal, fed, at rest – Digestion – Metabolism • Metabolic Energy Requirements (MER)
253
What can occur with Iodine pathologically? Is it during excess or during deficiency?
Paradoxically, both excess and deficiency can cause clinical signs of hypothyroidism.
254
What is ration adaptation, and what can you do to prevent the chronic negative implications?
 Over time, horses may adapt to high glycemic index foods  This results in higher insulin secretion and decreased insulin response  This has chronic negative implications  Appropriate diet: reduce high energy concentrates, fats can be included in small amounts, increase fiber and roughage  Pasture access should be eliminated or severely restricted until body weight is in the desired range  A muzzle could be used to limit feeding  Sudden feed restriction should be avoided- risk of hyperlipidemia/ Hyper TG
255
What can cause calcium deficiencies in dogs?
– secondary hyperparathyroidism, stimulates the secretion of parathyroid hormone – Increased production of calcitriol (active vitamin D) – PTH + Calcitriol= bone resorption • Skeletal fractures
256
What occurs with magnesium and calcium in grass tetany?
Low Mg2++ -\> less competition for Ca2++ at axon terminus so more acetylcholine is released, which allows for more vigorous, sustained muscle contracctions. Acetylcholine will not be broken down effectively since magnesium is needed as a cofactor for acetylcholinersterase. Sustained muscle contraction. Same occurs in cholinergic CNS so thats why you can see both tetany and seizures.
257
What is important about water soluable vitamins? How can they be obtained? How are they removed? What can increase the requirement?
• Water soluble vitamins are rarely deficient or in excess • Can be synthesized endogenously or by colonic microbes • Excess is filtered in the urine and excreted from the body • Requirement can increase if water intake is high or high energy requirements
258
What pathologic changes occur with aging?
- Cardiac disease - Endocrinopathies - Renal disease - Neoplastic disease - Osteoarthritis - GI disease - Dental disease
259
What can occur with excessive salt intake? What can cause eating of excessive salt? What are the signs/risks of salt toxicity?
Excess salt intake -\> drinking more water -\> more urine • Horses confined to the stall may eat salt out of boredom, may drink more and urinate more • Wet stall Salt toxicity - if water is not available or palatable. - colic - diarrhea - weakness - neuro signs
260
What are sources of Vitamin D?
• Sources – Liver – Fish- Cod Liver Oil – Egg Yolk – (Sunlight) – Most Pet Foods Add Cholecalciferol
261
What is ketosis? What are the clinical signs? What are your diagnostics? Prognosis?
Causes: - Can be primary - low carb diet - Secondary- unable to feed due to another issue. • Common underlying reasons: orthopedic, LDA/RDA, mastitis - High concentrations of FFA, Hypoglycemia, increased blood ketones. • Usually in lactation which drives requirements. Clinical signs: - vitals normal unless influenced by another primary disease. Decreased rumen motility, dry feces, dehydration, behavioral changes, dullness, nervousness ( can be dangerous to the vet) Diagnostic Results: * Ketones can be detected in the breath. Acetone smell. * Reagents and tablets, can detect kin milk * Ketonuria can be diagnosed with urine dip stick
262
How do you know if pigs are too close together when eating?
- No space exists between them, not everyone can fit into the feed line at the same time.
263
What is the treatment and prevention of laminitis?
 Treatment:  Stop fermentation- mineral oil, laxatives  Walk/gentle exercise if not painful or too sick  Banamine  Toxin binding medications- antibiotic polymyxin B can be given IV before toxins cross to the blood; di-tri-octahedral (DTO) smectite (Bio-Sponge) under research  Prevention:  Avoid high sugar/water soluble carbohydrate feed  Soaking hay in water and then removing the water can help reduce the water-solublecarbohydrate that may contribute to dysbiosis
264
What are the effects of the cold on pigs?
* Pig eats more feed: * Guide: 33g per day for every 1C below LCT * Growth rate is not affected at moderately low temperatures * Feed Conversion deteriorates • Lighter pigs are more sensitive to cold
265
What is the treatment of Rhabdomyolysis?
 Supportive care- fluids, adjust electrolytes, antioxidants?  Corticosteroids (if in shock)  Nutritional support:  Feed 1-2.5% BW/day  Limit starch to 10%  Limiting starch not only modifies fuel energy use in the muscle, but it also decreases excitability and nervousness  Increase fats (20-25% DE in fat)  Vegetable oils  Associated with decreased HR “calmness”  High fiber  A commercially prepared high-fiber, high-fat, low-starch diet should be offered on a regular basis  These diets are palatable, nutritionally balanced, and designed to maintain a horse’s weight - Reduce stress/ confinement - Allow regular exercise
266
What occurs with performance horses when they have high amounts of activity? What electrolytes should we be concerned about and what sources of electrolytes can we provide?
• More activity -\> more sweat-\> more electrolyte loss * Electrolytes of concern: Na, Cl, K, Mg, Ca * Legume hay provides Ca, Mg, K but low in Na * Grains- do not provide much electrolytes * Salt blocks * Added salt if sweating for over an hour 1-2 oz per hour
267
Why is fiber important horses? What is important about soluable fiber? Insoluable fiber?
Fiber is essential to regulate GI motility and provides substrate for the GI microbiota. Soluble fiber • acts as substrate for the microbiota • Usually results in increased stool water content • Pectin, gums •Insoluble fiber • Lower digestibility • Cellulose, hemicellulose, lignin • Produces volatile fatty acids that are absorbed (70% compared to ruminants)
268
What are the fat soluable vitamins? Where can they be found in general in adequate amounts. What can occur with storage? What is the issues with Fat soluable vitamins, and supplementation?
- Fat soluble vitamins A, D, E, and K - Generally present in adequate amounts in feed • Although can be reduced if stored for long periods - Greater risk for toxicity especially for vitamins A and D due to slow rates of excretion - Fat soluble vitamins share the same absorption mechanisms and can compete with each other
269
Who can be given uneaten creep feed?
Uneaten feed can be given to older pigs, but not sows (especially if medicated)
270
What is important to look at when assessing feeds?
* Physically assessing feed: appearance, smell * Feeds should be in sealed container * Appropriate temperature and moisture * Oil- sealed, protected from light and high temp * Hay- protected from rain/moisture * Alfalfa – inspect for toxic blister beetles (sometimes present) * Hay – leaf to stem ratio * First cut is less digestible, and leaves are smaller (less nutritious, more legnin) • Second and third cut- richer and more digestible, longer leaves * Hay quality – color (bright green is best; dark brown not good); mold (take core sample and send for testing to get representative sample) * Weigh the feed (not volume) (volume can be misleading) * Estimate pasture/grass intake * Can send a sample to lab analysis
271
What are the Atwater factors? What are the modified Atwater factors?
• Atwater Factors Protein= 4 kcal/g Fat= 9 kcal/g Carbohydrate= 4 kcal/g • Modified Atwater Factors Protein= 3.5 kcal/g Fat=8.5 kcal/g Carbohydrate= 3.5 kcal/g ( use if dog on commercial dog food)
272
Why do we give piglets creep feeding?
Normally weaning would take \>10 weeks but in commercial conditions it is done at 3-4 weeks and the gut is immature. - Sows milk peaks at 3 weeks and then slowly declines.
273
How much should you increase the feed of the mare during her final trimester? How much weight should a Quarterhorse or thoroughbred gain during pregnancy?
During last trimester increase 12-20% in intake • For Quarterhorse/ Thoroughbred mares an expected increase of 150-200 lbs. in bodyweight during pregnancy
274
In Nature: How much does the sow typically weigh? What is the timeframe piglets begin to be weaned? What is the growth rate? How long is gestation?
- 150 kg - Weaning \> 10 weeks - Growth rate is variable - Gestation 3 months, 3 weeks, 3 days
275
When do you start feeding creep feed? What are good tips to help improve piglets utilization?
• Start to feed from 16 days old • Feed fresh (feed 2x a day and remove uneaten food) in small amounts • Use a small tray feeder • Give creep when sow is feeding - Locate feeder away from heated creep area, the sow’s head, rear of sow
276
What is copper an important cofactor for? What does it do on its own? What can occur in excess?
Copper is important as a cofactor for Super Oxide Dismutase (SOD). Copper promotes oxidation on its own. Copper excess can cause liver and renal damage.
277
What are the goals of geriatric animals nutritionally?
– Appropriate energy and nutrients – Screen for organ system function
278
What are things to consider when formulating swine diets?
- Formulate to minimize cost maximizing growth. Lysine is the limiting amino acid in most swine diets - Feed is single most important cost to farm - Energy represents major part of cost formula
279
What can affect colostrum intake in piglets?
Birth weight: Heavier piglets more competitive and extract more from teats • Birth order: Earlier born piglets can get enough and compete less with later born • Litter size: Reduced intake per piglet as number increases
280
What occurs in hypercalcemia?
• Hypercalcemia causes increased production of calcitonin (important for bone deposition) and reduced PTH-\> slowed bone resorption • Although plasma Ca++ returns to normal, calcitonin will remain high • Paradoxically, this may result in hypocalcemia (due to increased bone deposition) -\> increase in PTH -\> increased bone resorption
281
What is bilious vomiting syndrome?
Dogs will have vomiting in the morning, and were fed in the afternoon/ evening and then are fasted until the morning. There is an increase secretion of bile acids and that irritates their GI tract and can cause the vomiting.
282
Why is training important in dogs?
Training increases stamina: – Ability to perform high intensity exercise – May not affect energy requirement • Training increases heart size and stroke volume -\> the HR is reduced during exercise • Training increases maximal oxygen utilization • Reduced lactic acid production • Hence fat supplementation as a source of energy is less helpful for untrained dogs
283
What is important abut magnesium in milk fever?
• Magnesium is important to have in diet at adequate amounts since it is an important cofactor for PTH.
284
What is the cause of hyperammonaemia?
– Arginine is required in the urea cycle – The enzymes the synthesize arginine have low activity in cats
285
What is a GILT?
Pig that has not had babies or been bred
286
How do you feed/ encourage feeding in a suckling sow?
* Avoid overfeeding during gestation * Keep house cool (20◦C) – once youngest piglets are over 2 days old * Water freely available – esp in first day /two * Keep feed fresh – no stale feed in troughs * Feed lactating sow diet * Feed at least twice, and ideally, 3 times daily * Provide 16 hours light (200 lux)
287
What is the function of vitamin E? What is oxidation of fat?
Antioxidant – Prevents oxidation of polyunsaturated fatty acids by donating electrons to the free radicals - Oxidation of Fat = Rancid Fat and Decreased Nutritional Value
288
What is a senior dog?
Completed 75-80% of life expectancy - Small dog 11.5 yr; medium 10 yr; large 9 yr; giant 7.5 yr Based on Goldstone and Allen and Roudebusch. This is controversial !!
289
What factors from low feeding intake can affect piglets? How?
Low feeding intake can lead to -\> lack of maternal nutrition -\> impairment of mucosal function. Impairment of mucosal function-\> uptake of antigens, toxins, translocation of bacteria, and maldigestion/ absorption. This overall can lead to poor performance, diarrhea and infections. Impairment of mucosal fxn can also lead to decreased brush border enzyme activity and absorption ability which also can lead to poor performance and diarrhea. IN SHORT: Low Feed intake -\> impairment of mucosal fxn -\> Bacterial proliferation/ decreased absorption -\> poor performance, diarrhea, and infection
290
What is the risk with refeeding a starved horse?What can you see with this? How can you do it safely?
- The horses can get refeeding syndrome, this risk is high in emaciated horses. Clinical signs are diarrhea, neurological signs. Prevention: - During refeeding use small portions of high quality forage offered at frequent intervals ( Q 4 hours) to stabilize insulin. - Use energy intake to promote weight gain, DER. - Diet suggestion: Combo of molasesses- free alfalfa product, good qyality soft leafy hay (early cut), good vitaminh and mineral supplement.
291
What are sources of Vitamin K?
• Source – Bacterial Synthesis in the Large Intestine – Green Leafy Plants – Liver – Fish Meal
292
What is the treatment of white muscle disease? What can be a potential issue?
• Selenium and vitamin E can be given prophylactically by muscular injection to foals at birth * Supplement in creep feed (feed Offered to nursing foals) * Supplement the mare’s feed • Vitamin E excess is uncommon (could reduce absorption of other fat-soluble vitamins Toxicity is potential issue -\> 5-10x requirement is toxic (narrow safety range)
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What is important about feeding geriatric horses? What issues can horse owners see in geriactric horses? What should you consider in terms of feed types?
Some horses remain physically active and healthy well into their twenties and others become “geriatric” by mid-teens  Older horses may lose weight and muscle mass although obesity is not uncommon  17% of owners reported weight loss in their elderly horse within the last 12 months  If the horse does not have an underlying metabolic disorder, there may be a benefit to a high caloric density and increased protein diet  Consider the use of more digestible forage (less mature grass hay)  Consider including highly digestible fiber sources such as beet pulp/soy hulls as means to increase the energy intake  Soaking and throwing away the water to reduce as far as possible the water-soluble carbohydrate intake as these may contribute to risks for colic and laminitis
294
What are equine probiotics? Do we use them? Why?
• Species that are commonly found in human probiotics or yoghurt include Lactobacillus, Bifidobacterium and Enterococcus are only 1% of the normal equine GI flora • Firmicutes are most abundant, but not used in most commercial probiotics • Most equine GI disease affect the large intestines so if bacteria does not survive it won’t be useful • Probiotics may not be safe in very young horses (\<2 mo) • Most evidence suggest that some probiotic Lactobacillus strains may survive the GI tract, but do not colonize it • Little evidence of probiotics in horses at present (especially in healthy horses)
295
TRUE or FALSE: Cats are able to utilize carotenoids for synthesis of vitamin A
FALSE Cats are unable to utilize carotenoids for the synthesis of vitamin A • They do not posses the enzyme which cleaves beta carotene (ᵝᵝ Caortene 15,15’ Dioxygenase)
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Wheere can you find Vitamin E in the food? What occurs with storing, heat processing or when you have high oil diets?
- High in leafy greens. * Usually sufficient in fresh pasture * Storage can cause degradation/oxidation * Heat processing can cause degradation * Diets with high fat/oil- increased vitamin E requirement to prevent oxidation.
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What can put racing or working animals at a disadvantage?
• Being overweight is a disadvantage in long distance physical activity. - Can increase dehydration risk.
298
What are some examples of diseases seen in Labrador?
Labrador- orthopedic disease, copper storage disease
299
What is the treatment of salt toxicity?
Slow ingestion of saline free water? If too rapid, cellular edema can occur - Neuro signs
300
What is hyperlipidemia? What is the clinical signs? Who is more at risk?
Hyperlipidemia is common in overweight ponies and in mares  Horses may be thin whereas ponies are often overweight  Many times secondary to stress, disease, pregnancy, lactation or poor feed intake  Clinical signs:  Inappetence  Dullness  Depression  Poor feed intake  Colic  Can cause liver failure
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What should you not do in terms of grain, when feeding performance horses?
Do not feed more grain than forage.
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What are potential orthopedic issues in foals in there potential causes?
* Could be the result of accelerated growth * Genetic trait * Common conformational abnormalities: * Toe in * Straight fetlock * Nutritional factors: excess and/or deficiency * Vitamin A * Vitamin D * Calcium * Phosphorous * Mg * Copper * Zinc * Other Causes * Energy excess: Above 120% the requirement according to the NRC * Protein excess? No evidence in foals (or dogs) * Carbohydrate excess? • Increased insulin secretion * Affects growth plate structure
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In what conditon SHOULDN’T you feed ad libitum?
If body condition score is very low.
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What should you base diets off of in both dogs and cats?
• Dogs and cats have unique nutritional requirements that reflect their natural diets • Dogs’ and cats’ diets should be adjusted as needed for age, body condition, and lifestyle
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What indicates pigs comfort?
* Lying Behaviour * Comfortable: Lie apart on side and barely touching * Cold: Lie on sternum * Very Cold: Huddling and lie on top of one another * Drafts: aggressive behavior and tail-biting
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What is the relationship of lactation and glucose demand? Lactose and milk production?
- Higher lactation (or lactation in general), more milk produced. More lactose more volume of milk. Glucose + galactose = lactose
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What can occur if performance horses are given too much protien durring warm weather?
This will decrease performance
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What are important considerations when creating a diet and feeding schedule?
- Separate feeding and exercise • Provide highly absorbable carbohydrates during prolonged exercise
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What can fat catabolism cause\>
Spares protien, - Can lead to hyperlipidemia - Increased risk in overweight horses/ ponies - Can occur in illness, during lactation
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What is the importance of fiber and carbohydrates?
* Carbohydrates are calculated and not measured * Crude fiber analysis- provides an indication for insoluble fiber * No information on soluble fiber * Total dietary fiber- soluble and insoluble fiber
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What happens to hay that is heated or gets wet? What is the Maillard reaction?
Hay that is heated or gets wet decreases in protien digestibility. Maillard reaction is a reaction between priotiens and sugars. This will change color and taste but decrease digestibility.
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What is included in the diet of performance horses?
* Combination of carbohydrate sources: * Legume grass, green grass, and grains [high energy] * VFA * Oils [10% dry matter] 20% of all energy intake Protein: • Protein requirements are increased in performance horses • Protein is thermogenic • Can negatively affect performance in warm weather • $$$ • High protein feed: alfalfa (legume hay), grass hay, oat hay, grain
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How do you choose pet food?
• Who formulates the diet? • Can you provide a complete analysis? • What quality control is done? • What is the caloric content? • What research was done to develop this product?
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What is the response of a horse with EMS that eats a high carbohydrate meal?
- Horses with EMS respond to high carbohydrate meals with an exaggerated increase in insulin and higher than normal blood glucose that tapers slowly  Associated signs include infertility, altered ovarian activity, and increased appetite  Can also cause hypertriglyceridemia, increased serum concentrations of leptin, and arterial hypertension  While the cause of this syndrome is not entirely known or understood, obesity appears to be an important risk factor
316
What are the protien requirements for horses? How is protien analyzed?
Protien is often analyzed as nitrogen x 6.25 ( nitrogen is 16% of protien) - Protien requirement is really essential amino acids + nitrogen requirement that is used as building block to synthesize non essential amino acids. - Mature horse, relies on colonic conversion of Nitrogen to synthesize essentil if there is enough dietary N. - Foals, reproductive mqares, and other physiogical demanding life stages rely on combination of essential AA from diet and colonic production.
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What are potential complications of EMS? What is the diagnosis?
 Experimentally, high blood insulin levels lead to laminitis due to vasoregulatory actions  Insulin resistance can decrease nitric oxide production and promote vasoconstriction  EMS may be a predisposing factor for pituitary pars intermedia dysfunction (PPID; equine Cushing’s disease)  Diagnosis: oral sugar test (OST) or oral glucose test (OGT) (fasted for 3-12 hours, then given corn syrup and blood drawn at 60 mins, and 90 mins)
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When should H2O be available for donkeys?
* Water should be available in all times when possible * While donkeys are quite resilient and resist dehydration, this is not recommended DON'T DEHYDRATE DONKEY DDD
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What can be seen clinically due to vitamin D deficiency? Excess?
Deficiency Clinical signs: – Rickets (vit D deficiency) – Osteomalacia (decrease bone mineralization, low absorption of calcium) (non fusion of growth plates- need vitamin D for fusion) – Nutritional Secondary Hyperparathyroidism (Ca deficiency) ( fusion of growthplates) • Excess (young and old animals) Vitamin D has narrow safety margin. – Hypercalcemia – Bone Resorption – Soft Tissue Calcification
320
What can increase water loss in urine/ evaporation?
Exercise
321
What is the process of silage and haylage production?
• THE PROCESS OF SILAGE AND HAYLAGE PRODUCTION IS CALLED ENSILING • THE CROPS ARE CUT CHOPPED AND THEN REMOVED FROM THE FIELD • THE MATERIAL IS THEN SEALED IN A SILO OR EVEN A BAG AND LEFT TO FERMENT UNDER ANAEROBIC CONDITIONS • ACID ACTS AS A PRESERVATIVE AND INHIBITS GROWTH OF MOLD AND BACTERIA • AFTER BEING CHOPPED, THE SILAGE IS PACKED DOWN (SOMETIMES WITH A VEHICLE) • A THICK TARP AND OLD TIRES ARE PLACED OVER THE SILAGE TO PREVENT OXYGEN FROM PENETRATING • THE COVER IS VITAL TO PREVENT OXYGEN AND EXCESS MOISTURE PENETRATION • THE MICROBES THAT THRIVE IN THESE CONDITIONS CREATE ORGANIC ACIDS (MOST OF THESE VFA) • LOW PH PREVENTS GROWTH OF MOLD AND BACTERIA
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What are important ways to prevent foal orthopedic disease?
Prevention: * Maintain an ideal BCS (4/9) * Ideal growth rate estimates: * Suckling foals \<1.1 kg per day * Weanling foals \<0.75 kg per day * Prevent rapid growth * Early intervention as needed
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What can occur with low potassium? What can casue it? Is high potassium due to diet common?
hypoklemia can cause: Inappetence, fatigue, weakness, lethargy. Can occur with excess sweating (increased aldasterone secretion, increased Na+ retention, increased potassium excretion), diuretics, diarrhea.
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What is feedstuff? What is ration/ daily ration?
* FEEDSTUFF= COMPONENTS OF THE DIET * RATION/ DAILY RATION= ALL FEEDSTUFF OFFERED DURING A 24 HOUR PERIOD
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What are NEFA levels?
• Measure NEFA is blood at various intervals pre and post partum at random to make sure they are receiving essential nutrition. - If more than 40% of cows in group are above normal values this indicates a problem. How to improve: increase energy density, review BCS in mid lactation and dry cows, ensure sufficient space per cow, make sure feed is always available.
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What is present at the catalytic site of glutathione peroxidase?
Selenocysteine
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What is the treatment of hypomagnesemic tetany? What is the prevention?
• Magnesium SO4 via rectum as well as Calcium/ magnesium salt solution. Wear boots and get ready to run ( Salts can cause diarrhea and the cows can wake up aggressive) IV magnesium slowly Prevention: - one gram elemental magnesium absorbed per head per day.
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What occurs during the first month of life for ruminants? What are they considered? What is milk curdled by?
* Breaks down particles to smaller size. Smaller more dense material is pushed to the reticulum through the reticulo-omasal orifice into the omasum. * For first month of life, ruminant is functionally a mono-gastric animal. If milk goes to rumen it rots. Closure of gastric groove directs milk from esophagus to the omasum. Stomach milk is curdled by rennin and eventually digested.
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What is used to empirically prevent diarrhea in piglets? What else can be done to prevent diarrhea in piglets?
- ZnO is empirically used to prevent diarrhea at x10 times nutritional levels • Reduce protein • Use only extruded soy, use milk products (whey, lactose) and fish meal or other high quality protein sources • Use feed additives like acidifiers, pre and probiotics, enzymes… • Start he first week with electrolyte solutions and porridge like presentations
330
What is fermentation? Where does it take place? Who does it take place in?
• THE HINDGUT IN THE HORSE, RABBIT AND RODENT • THE FORESTOMACH IN CAMELIDS AND RUMINANTS • FERMENTATION IS AN ANAEROBIC PROCESS WHERE THE SUBSTRATE IS BROKEN DOWN TO SIMPLER COMPOUNDS BY MICROBIAL ENZYMES SUCH AS CELLULASE. • ORGANIC ACIDS (VOLATILE FATTY ACIDS; VFA) ARE AVAILABLE FOR USE BY THE HOST
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What is the ideal BCS for a weanling foal?
4/9
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What are easily digested in the small intestines. What breaks down starches and carbohydrates, where are they absorbed in horses? What can excessive carbohydrate intake lead to?
Carbohydrates - Starch and sugar are easily digested in the small intestines • Amylase breaks down starch and carbohydrates are absorbed in the brush border * Excessive carbohydrate intake can lead to GI dysbiosis * Colic * Laminitis * Diarrhea
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What is crude fiber analysis?
- Crude fiber is analysis of a portion of the insoluble fiber • Does not represent all the fiber in the food
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What is the protein maintenance requirement? Where can energy be from if there is is poor feed intake?
Maintenance requirement: 40g CP/Mcal In case of poor feed intake amino acids may be oxidized for energy.
335
What is important about the environmental conditions of finishing pigs?
* Lower Critical Temperature (LCT): Temperature below which pigs uses extra feed to maintain body temperature * Thermoneutral Zone: Range within which temperature does not affect pig performance
336
What is important about theobromine toxicity? What are initial clinical signs? What are progressive clinical signs? What is the treatment?
Theobromine is a methylxanthine found in chocolate and coffee. Initial clinical signs: polydipsia, vomiting, diarrhea, abdominal distention, restlessness Progressive signs: Hyperactivity, polyuria, ataxia, rigidity, tremors, and seizures. Tachycardia, VPC's, tachypnea, cyanosis, hypertension, hyperthermia, bradycardia, hypotension, or coma. Treatment: Symptomatic supportive care, anti seizure medication, activated charcoal when stable. Extra info: NOT NEEDED FOR EXAM \*\* Can increase intracellular calcium levels. Theobromine and caffeine competitively inhibit cellular adenosine receptors, which stimulate CNS stimulation, diuresis, and tachycardia. Reported to have severe signs at 100-200 mg/kg but can cause severe signs/ death at lower doses.\*\*\*
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What can cause calcium excess?
Calcium Excess – Developmental skeletal abnormalities (puppies)
338
What is silage inoculants? What do they do?
THERE ARE THOSE WHO USE SILAGE INOCULANTS (A SEED OF BACTERIA FROM ANOTHER SILAGE) • THESE CAN EXPEDITE FERMENTATION, LIMIT MOLD AND SPOILAGE
339
What is fatty liver disease? What are the clinical signs?What is the treatments?
Can occur with cows with normal BCS, and is a result of prolonged negative energy balance in the immediate period before and after calving. - Result of decreased appetite and high energy needs during lactation. - Happens quicker in obease animals. High access of FFA, the ketone synthesis pathways become saturated. Clinical signs: - Usually after calving - Depression - Anorexia - Weight loss - Decreased GI/ rumen motility - Weakness Treatment: - Same as ketosis, but more severe so requires more intensive care - No propylene glycol -\> cannot metabolize it - Cows with high BCS should be encouraged to lose weight. Treatment is costly and long. - Put pedometers on cow, and move feed/ water on opposite sides of pen to make them increase exercise.
340
What are important aspects of feeding management to consider?
* Frequency * Timing * Location * Method
341
What occurs in piglets between 3-6 weeks?
decrease in immunity, decrease enzyme activity, increased vulnerability.
342
What are important considerations about colic, how can you try to resolve prior to surgical intervention, what other interventions can occur to help the horse improve?
- Equine colic may be considered medical when it can resolve without surgery, or surgical when there is an impaction that does not respond to medical care  Medical treatment is appropriate if the horse is mildly painful and the cardiovascular system is functioning normally  If evidence of intestinal obstruction with dry ingesta is found on rectal examination, a primary aim of treatment is to rehydrate and evacuate the intestinal contents  If the horse is very painful- pain must be addressed as pain can negatively affect GI motility  Address hydration and electrolyte abnormalities if present  A nasogastric tube may be passed to relive gas
343
What can you do to straw to increase digestibility? Why does this increase digestibility?
STRAW CAN BE CHOPPED TO SMALL PIECES WHICH INCREASES ITS SURFACE AREA AND INCREASES DIGESTIBILITY • CHOPPED STRAW CAN BE ADDED TO THE RATION OF LIVESTOCK AS A SOURCE OF PARTIALLY DIGESTIBLE FIBER
344
How is energy used in running dogs?
• Initially- ATP (first 10 sec) • Aerobic metabolism – primarily carbohydrates and fat. • Anaerobic metabolism- primarily carbohydrates – Anaerobic metabolism is rapid, but only produces 2 ATP from each Glucose – Lactic acid production
345
What would loss of back fat indicate? What can influence it?
• Loss of fat cover over each parity • Result is sows with very poor back-fats at weaning • Poor reproductive performance = higher culling rates • Back fat at weaning is also influenced by feeding in pregnancy and lactation STARTING HER BREEDING AT IDEAL BCS WILL GIVE YOU MORE LITTERS BEFORE SHE IS TOO THIN
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Where does energy come from?
Chemical bonds from Fat, Carbohydrates, and proteins
347
What can you use to supplement vitamins? When would additional vitamin supplementation be beneficial?
* Grain mixtures are usually fortified with vitamins * High energy-\> be careful with over-supplementation (can be Expensive) * Additional vitamin supplements could be beneficial if: * Hay/ feed quality is poor or stored for long * Colic/GI disease -\> dysbiosis (less bacterial microflora so less synthesis of vitamins so supplements are important.) * Antibiotics -\> dysbiosis (destruction of gut microflora)
348
Where else can taurine be lost? What influences recovery from the bile?
– Loss of taurine in the bile - Cat foods cooked in cans which could make some proteins less digestible. • Recovery of taurine from the bile depends on protein digestibility – High levels of indigestible protein promotes gut flora which degrades taurine – Therefore taurine requirement depends on the diet and the processing – canned diets require double the amount of taurine!
349
What can occur with hypomagnesemic tetany, how can you treat it, and who is more susceptible?
Can cause paralysis of limbs, grass tetany is example. Treatment: Magnesium and Calcium supplementation. More susceptible: Lactating Mares, Fasted animals in transport, animals exposed to young pastures or K+ enriched pastures.
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What are NSC's ( non structural carbohydrates)?
* NSC ARE THE CARBOHYDRATES THAT DO NOT SUPPORT THE BUILDING FOUNDATIONS OF THE PLANT * AS SUCH THEY ARE USUALLY MORE DIGESTIBLE • WATER-SOLUBLE CARBOHYDRATE (WSC) ARE A FRACTION OF THE NSC * THESE ARE REDUCED WHEN HAY IS SOAKED IN WATER • BEET PULP IS ENERGY DENSE (MORE THAN GRASS HAY) AND HAS A LOW NSC CONTENT * IN CONTRAST, RICE BRAN IS AN ENERGY DENSE FEED BUT HAS A HIGHER NSC CONTENT
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What is important to note about horses and salt?
• Horse has an appetite for salt and will consume adequate amounts if it is available
352
What do carbohydrates provide to the animal? What is a good source of energy with high glycemic index? What is a potential issue with excess carbohydrates? What is the benefit of adequate carbohydrates?
• Carbohydrates provide energy – Maltodextrin provide a source of energy with high glycemic index -\> high uptake – Replenishing muscle glycogen stores, less muscle breakdown – Can lead to diarrhea in high amounts
353
What is important to make sure of when providing dogs with additional protein?
- Protein should be highly digestible and with a good amino acid profile – Excess indigestible protein will ferment in the large colon and may lead to diarrhea
354
What is hypophosphotemic rickets? Who is more susceptible?
* More common in young animals. Camelids * More likely occurs in dark finer llamas due to UV not penetrating their darker skin as well. This is problem in pacific northwest and occurs primarily in the winter. Without Vitamin D, inadequate Ca and Phos absorption from gut to mineralize bones. Results in microfractures, wich cause lameness and angular deformities of the long bones. Clinical signs: - Reluctant to play, lethargic, Diagnostic indications: - Widened growth plates and flared metaphyses are hallmark signs - Typically normal serum calcium, low serum phosphorus
355
What kind of muscle fibers do dogs have and how does that affect their running ability/ consequences of running? How are people different?
• Dog muscle does not contain the anaerobic, easily fatigued type IIb fast twitch fibers which are adapted to sprinting – Type IIa fast twitch fibers rely more on anaerobic than aerobic metabolism – Type I slow twitch fibers rely more on aerobic than anaerobic metabolism • As a result lactic acid production in exercising dogs is low, unless they perform supramaximal exercise
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Who is more suceptible to oxalate poisoning?
- Sheep are most susceptible * Livestock should be adapted to oxalate plants over 4 days incrementally increasing time allowed to graze these plants. * Becomes more resistant to these plants over time.
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What supplementation is given to race horses and foals and can be harmful to the foal? What can it cause?
• Iron deficiency is uncommon • Supplementation: given to race-horses and foals • Can be harmful in foals and is unnecessary (can cause liver failure in foals)
358
What will happen to back fat after each litter?
It will decrease
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What are carbohydrates metabolized to in the rumen? What VFA is converted to glucose? How?
- Fermentation of carbohydrates to VFA's (alot) - Propionate (VFA) is metabolized to glucose via hepatic gluconeogenesis. • Butyrate and acetate cannot be converted to glucose. • Provides \> 70 % energy supply