Exam 2 Flashcards
(189 cards)
a syndrome caused by brain disease, evidenced by chronic personality disintegration, confusion, memory impairment, and deteriration of intellectual capacity and function
dementia
a chronic, progressive, degenerative disease of the brain
Alzheimer’s disease (AD)
a rare and fatal brain disorder caused by a prion protein
Creutzfeldt-Jakob disease
a mental state characterized by a disturbance of cognition, which is manifested by confusion, excitement, disorientation, and a clouding of consciousness/ hallucinations and illusions are common
delirium
a condition characterized by the presence of Lewy bodies (abnormal deposits of the protein a-synuclein) in the brainstem and cortex- this disease has features of both AD and Parkinson’s
dementia with Lewy bodies
familial Alzheimer’s disease
individuals with a clear pattern of inheritance within a family for developing Alzheimer’s
a rare disorder caused by shrinking frontal and temporal lobes of the brain; characterized by disturbances in behavior, sleep, personality, and eventually memory
frontotemporal lobar degeneration (FTLD)
mild cognitive impairment (MCI)
a stage of cognition and funcitional ability between normal aging and early Alzheimer’s disease
mixed dementia
presentation of two or more types of dementia simultaneously
neurofibrillary tangles
tangled bundles of fibers seen in the cytoplasm of abnormal neurons in those areas of the brain most affected by Alzheimer’s disease
normal pressure hydrocephalus
an uncommon disorder characterized by an obstruction in the flow of cerebrospinal fluid; causes a buildup of this fluid in the brain
retrogenesis
the process in AD patients in which degenerative changes occur in the reverse order in which they were acquired
sundowning
a condition in which the individual becomes more confused and agitated in the late afternoon or evening
vascular dementia
the loss of cognitive function resulting from ischemic, ischemic-hypoxic, or hemorrhagic brain lesions caused by cardiovascular disease
prion
small infectious pathogen containing protein but lacking nucleic acids
Dementia is defines as a
a. syndrome that resuts only in memory loss
b. disease associated with abrupt changes in behavior
c. disease that is always due to reduced blood flow to the brain
d. syndrome characterized by cognitive dysfunction and loss of memory
D. syndrome characterized by cognitive dysfunction and loss of memory
Vascular dementia is associated with
a. transient ischemic attacks
b. bacterial or viral infection of neuronal tissue
c. cognitive changes secondary to cerebral ischemia
d. abrupt changes in cognitive function that are irreversible
C. cognitive changes secondary to cerebral ischemia
The clinical diagnosis of dementia is based on
a. CT or MRS
b. brain biopsy
c. electroencephalogram
d. patient history and cognitive assessment
D. patient history and cognitive assessment
Which statement(s) accurately describe(s) mild cognitive impairment?
a. always progresses to AD
b. caused by variety of factors and may progress to AD
c. should be aggressively treated with acetylcholinesterase drugs
d. caused by vascular infarcts that, if treated, will delay progression to AD
e. patient is usually not aware that there is a problem with his or her memory
B. caused by variety of factors and may progress to AD
The early stage of AD is characterized by
a. no noticeable change in behavior
b. memory problems and mild confusion
c. increased time spent sleeping or in bed
d. incontinence, agitation, and wandering behavior
B. memory problems and mild confusion
A major goal of treatment for the patient with AD is to
a. maintain patient safety
b. maintain or increase body weight
c. return to a higher level of self care
d. enhance functional ability over time
A. maitain patient safety
Creutzfeldt-Jakob disease is characterized by
a. remissions and exacerbations over many years
b. memory impairment, muscle jerks, and blindness
c. parkinsonian symptoms, including muscle rigidity and tremors at rest
d. increased intracranial pressure secondary to decreased CSF drainage
B. memory impairment, muscle jerks, and blindness
Which patient is most at risk for developing delirium?
a. a 50 year old woman with cholecystitis
b. a 19 year old man with a fractured femur
c. a 42 year old woman having an elective hysterectomy
d. a 78 year old man admitted to the medical unit with complications related to heart failure
D. a 78 year old man admitte to the medical unit with complications related to heart failure
amnesia
an inability to recall important personal information that is too extensive to be explained by ordinary forgetfulness- the condition may be temporary or permanent, depending on etiology