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Flashcards in Exam 2 Deck (229)
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1

What is the only parasitic protozoan of the small intestine?

Giardia lamblia

2

steatorrhea-

fatty stool

3

does giardia feed on host tissues?

no

4

What host immune response is elicited against giardia?

IgA

5

What microscopy shows giardia covering GI tract?

SEM

6

When will you see giardia trophs in fecal sample?

watery diarrhea (not enough time to encyst)

7

Which tests are for giardia in GI tract?

ELISA for parasite antigen
string test (enterotest)

8

Rx for giardia:

Flagyl (metronidazole)
Tindamax (tinidazole) = DOC
Nitazoxanide
Furazolidone-for children

9

Which two giardia drugs cant be taken with alcohol?

flagyl and tindamax

10

The commensal oral trichomonad?

T. tenax

11

The commensal GI trichomonad?

P. hominis

12

Trichomonas vaginalis:

vagina and urethra of females
urethra, seminal vesicles and prostate of male

13

vaginalis trichomoniasis
•Transmission:
•Trophs cannot survive outside host

sexual contact

14

What is pathology of T. vaginalis?

lyses and eats epithelial cells

15

Dx. of T. vaginalis

-wet mount of genital secretions
-OSOM Trichomonas Rapid Test (ELISA tests for parasite antigen, doctor can do this test)
-anaerobic in vitro culture

16

transmission can occur congenitally, but.....

parasite does not cross placenta or cervix. infant is infected during birth. RARE

17

Rx for Trichomonas vaginalis

Flagyl. 7 day bid or tid (2x a day or 3x a day)
no immunity

18

why is a lysosomal response not initiated in a cell invaded by an apicomplexan

they force their way in, they are not endocytized

19

Apicoplast is considered to be a relic of a:

chloroplast

20

During schizogony, multiple ______ occur, but only one ____ occurs

nuclear divisions
cytokinesis (into as many parts as there are nuclei)

21

chickens infected with eimeria contract "bloody cecum" aka:

cecal coccidiosis

22

ingestion of what stage of eimeria infects chickens?

sporulated oocyst

23

Chicken host defenses against eimeria:

shed epithelial cells, pass with feces before invading cell, macrophages kill a few

24

Isospora belli is now called:

Cystoisospora belli

25

Isospora belli
-Only Isospora species to infect man!
oDistribution:
oNiche:
oDx:
oRx:

-Tropical regions (NOT IN USA)
- small intestine
-oocysts in fecal samples (external sporulation)
-TMP-SMX (Trimethoprim-sulfamethoxazole. A.k.a. Bactrim/ Septra/ Cotrim)

26

What kind of people do Isospora belli infect?

young, old, immunocompromised. Uncommon in immunocompetent

27

considered an "emerging" pathogen

cyclospora cayetanensis

28

Cyclospora cayetanensis
distribution-
niche-
symptoms-
-it is self limiting
-sources-

-worldwide
-small intestine
-explosive diarrhea
-contaminated food and water

29

Cyclospora catayensis
sporgony occurs where-
oocyst contains what composition of sporozoites/sporocysts-
oocysts are very ______- not easily visualized in unstained fecal sample.

-external
-2 sporocysts with 2 sporozoites each
-refractile

30

cyclospora cayetanensis
Dx.-
Rx.-

-acid fast stain fecal smear
-TMP-SMX