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Pharm II > Exam 2- Drug Class General > Flashcards

Exam 2- Drug Class General Flashcards

1
Q

What drug class is acetazolamide?

A

CA inhibitor (short-term diuretic)

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2
Q

What drug class is dorzolamide?

A

CA inhibitor (short-term diuretic)

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3
Q

What drug class is brinzolamide?

A

CA inhibitor (short-term diuretic)

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4
Q

What drug class is furosemide?

A

Loop diuretic

Inhibit NKCC2 in thick ascending limb of LOH

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5
Q

What drug class is ethacrynic?

A

Loop diuretic

Inhibit NKCC2 in thick ascending limb of LOH

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6
Q

What drug class is metolazone?

A

Thiazides diuretic

Inhibit NaCl in early distal tubule

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7
Q

What drug class is indapamide?

A

Thiazides diuretic
Inhibit NaCl in early distal tubule

Excreted by biliary system, useful for pts with renal insufficiency
Does not increase lipids
Pronounced vasodilation

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8
Q

What drug class is spironlactone?

A

Aldosterone antagonist

Competitive inhibitor of aldosterone

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9
Q

What drug class is eplerenone?

A

Aldosterone antagonist

Selective aldosterone receptor antagonist

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10
Q

What drug class is Amiloride?

A

Direct inhibitor of Na influx

Inhibits Na/K exchange independently of aldosterone

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11
Q

What drug class is mannitol?

A

Osmotic diuretic

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12
Q

What drug class is isosorbide?

A

Osmotic diuretic

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13
Q

What drug class is glycerin?

A

Osmotic diuretic

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14
Q

What drug class is urea?

A

Osmotic diuretic

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15
Q

What drug class is desmopressin?

A

ADH agonist

Activates V2 receptors (central DI)

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16
Q

What drug class is conivaptan?

A

ADH antagonist

Non peptide V1a and V2 receptor antagonist (SIADH)

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17
Q

What drug class is tolvaptan?

A

ADH antagonist

Non peptide V2 receptor antagonist

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18
Q

What type of drug is enalapril?

A

ACEI

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19
Q

What drug class is losartan?

A

ARB

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20
Q

What drug class is sacubitril/Valsartan?

A

ARNI

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21
Q

What type of drug is dobutamine?

A

Sympathomimetic

Selective B1 agonist

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22
Q

What drug class is dopamine?

A

Sympathomimetic
Low dose D1
Mod dose B1
High dose A

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23
Q

What drug class is digoxin?

A

Digitalis

Inhibit Na/K pump

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24
Q

What type of drug is clonidine?

A

Centrally acting sympatholytic

Stimulate medically A2 receptors

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25
Q

What drug class is methylodopa?

A

Centrally acting sympatholytics
Stimulate medullary A2 receptors?
Safe in pregnancy

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26
Q

What drug class is prazosin?

A

A1 agonist

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27
Q

What drug class is labetalol?

A

Combined A1 and b blocker

Safe in pregnancy

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28
Q

What drug class is carvediol?

A

Combined A1 and b blocker

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29
Q

What drug class is hydralazine?

A

Vasodilator (arteries)

Safe in pregnancy

30
Q

What drug class is sodium nitroprusside?

A

Vasodilator (arteries and veins) and Nitrate/Nitrite

31
Q

What drug class is fenoldapam?

A

D1 agonist (vasodilates arteries)

32
Q

What drug class are Nifedipine is Amlodipine?

A

CCB
More effect on vessels (more likely to produce reflex tachycardia)
Nifedipine is safe in pregnancy

33
Q

What drug class is diltiazem?

A

CCB

34
Q

What drug class is verapamil?

A

CCB

More effect on cardiac tissue

35
Q

What drug class is ranolazine?

A

Partial fatty acid oxidation inhibitor

Last choice for tx of angina

36
Q

What drug class is silfenafil (viagra)?

A

PDE5 inhibitor

37
Q

What drug class is vardenafil?

A

PDE5 inhibitor (more selective, fastest acting)

38
Q

What drug class is tadalafil?

A

PDE5 inhibitor (more selective, longest acting)

39
Q

What drug class are statins?

A

HMG-Co reductive inhibitors (decrease LDL)

40
Q

What drug class is cholestyramine?

A

Bile acid binding resins (safe in pregnancy)

41
Q

What drug class is niacin?

A

Drugs that impair synthesis of lipoproteins (increase HDL)

42
Q

What drug class is gemfibrozil?

A

Fibrin acid derivative (decreases triglycerides)

PPAR-a ligand that up-regulates lipoprotein lipase

43
Q

What drug class is ezetimibe?

A

Inhibitor of cholesterol absorption (only used in combo with a statin, doesn’t decrease CV mortality)

44
Q

What drug class is alirocumab?

A

PCSK9 inhibitor

45
Q

What drug class is evolocumab?

A

PCSK9 inhibitor

46
Q

What type of drug is quinidine?

A

Class IA anti-arrhythmic

Binds to activated Na channels

47
Q

What type of drug is procainamide?

A

Class IA anti-arrhythmic

Binds to activated Na channels

48
Q

What drug class is lidocaine?

A

Class IB anti-arrhythmic

Blocks inactivated Na channels

49
Q

What drug class is flecainide?

A

Class IC anti-arrhythmic

Blocks all Na channels

50
Q

What drug class is propanolol (in regards to anti-arrhythmic)?

A

Class II anti-arrhythmic

Non specific b blocker

51
Q

What drug class is metoprolol (in regards to anti-arrhythmic)

A

Class II anti-arrhythmic

B1 blocker

52
Q

What drug class is esmolol (in regards to anti-arrhythmic)?

A

Class II anti-arrhythmic

B1 blocker

53
Q

What drug class is amidarone?

A

Class III anti-arrhythmic

Blacks K channels

54
Q

What drug class is sotalol?

A

Class III anti-arrhythmic

Blocks K channels

55
Q

What is adenosine used for?

A

DOC for acute PSVT and WCW

Effective for only reentry arrhythmias

56
Q

What is magnesium used for?

A

DOC for tosades de pointes

57
Q

What drug class is enoxaprin?

A

LMWH (inhibits Xa)

58
Q

What drug class is fondaparnux?

A

LMWH (inhibits Xa)

59
Q

What drug class is dabigatran?

A

Oral direct thrombin inhibitor

60
Q

What drug class is rivaroxaban?

A

Oral direct factor Xa inhibitor

61
Q

What drug class is apixaban?

A

Oral direct factor Xa inhibitor

62
Q

What drug class is heparin?

A

HMWH (binds to antithrombin III, causing it to inactivate clotting factors, mainly Xa thrombin)

63
Q

What drug class is warfarin?

A

Clotting factor synthesis inhibitor

Inhibits reduction of vitamin K and interferes with synthesis of II, VII, IX, X and protein C/S

64
Q

What drug class is alteplase or tPA?

A

Fibrinolytic agent

Converts plasminogen to plasmin

65
Q

What drug class is aminocaprotic acid?

A

Antifibrolytics

Inhibits plasminogen activation

66
Q

What drug class is tranexamic acid?

A

Antifibrinolytic

Inhibits plasminogen activation

67
Q

What drug class is aspirin?

A

Antiplatelet

Irreversible COX inhibitor

68
Q

What drug class is clopidogrel?

A

Antiplatelet

Irreversibly blocks the ADP receptor on platelets

69
Q

What drug class is ticagrelor?

A

Antiplatelet

Irreversibly blocks the ADP receptor on platelets

70
Q

What drug class is abciximab?

A

Antiplatelet

Prevents GP IIb/IIIa from binding fibrinogen

Pharm II (10 decks)

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