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Flashcards in Exam 2 SHOCK Deck (29)
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1
Q

Shock is?

A

Inadequate tissue perfusion:

Not enough O2 delivered to tissues to meet demand

2
Q

Shock results in?

A

Acidosis from anaerobic metabolism ->

hypoTN

3
Q

Direct determinants of Shock are?

A

CO
O2 saturation
Hgb levels

4
Q

What is NOT a direct determinant of Shock?

A

BP

5
Q

O2 delivery (DO2) is a direct fxn of what?

A

DO2 = CO x CaO2

CaO2 = arterial gas content

6
Q

Direct determinants of BP are?

A

CO
Preload
Peripheral vascular resistance

7
Q

What is NOT a direct determinant of BP?

A

O2 sat

8
Q

Shock presentation? (4)

A

1) Tachycard
2) Tachypnea
3) +/- hypoTN
4) Sxs of ↓ end organ perfusion:
∆ mental status
↓ urine
Lactic acidosis
Cool/mottled extremities
Thready pulse

9
Q

Methods of ↑ DO2 (supply)? (2)

A

Maximize CO:
Pre/After loads
Contractility
HR

Maximize CaO2:
Hct
Supplement O2

10
Q

Methods of ↓ VO2 (demand)? (3)

A

Treat fever
Support respiratory effort
Sedation/Pain control

11
Q

Causes of Shock: Cardiogenic? (3)

A

↓ cardio fxn
Arrhy
Obstruction

12
Q

Causes of Shock: Hypovolemic? (6)

A
Hemorrhage
Over-diuresis (DM, DI)
D/V
Dehydration
DKA
Burns
13
Q

Causes of Shock: Septic?

A

Exaggerated response to Infection

14
Q

Hypovol Shock: Compensation mechanisms?

A

GOAL is to maintain CO

Barorecept-mediated vasoconstriction:

↑ Epi/Renin/ADH ->
Tachycard
Tachypnea
Narrowed pulse pressure
↓ urine output
15
Q

Hypovol Shock from Hemorrage: Compensated/Non-Progressive is?

Body’s response?

A

< 20% loss

BP maintained w/ vasoconstriction, ↑ flow to vital organs

CO maintained w/ ↑ stroke vol, slight ↑HR

16
Q

Hypovol Shock from Hemorrage: Non-Compensated/Progressive is?

Body’s response?

A

20 - 40% loss

↓ vol = inadequate preload, too low to overcome w/ ↑ contractility and CO

SNS/Neurohormonal response inadequate to overcome w/ ↑ vasoconstriction

= acidosis, mental ∆s, ↓↓ urine output

17
Q

Hypovol Shock from Hemorrage: Profound/Irreversible is?

Body’s response?

A

> 40% loss

↓↓ or no BP
↑↑ tachy
Lethargic

18
Q

Cardiogenic Shock hypoTN BP?

A

< 90/60

19
Q

Septic Shock results in? (3)

A

Circulatory collapse
Multi organ fail
Death (>35% w/ hypoTN, 45% w/ sustained)

20
Q

Septic Shock: Body’s response

Preload?

CO?

Afterload?

BP?

Organ Perfusion?

A

Preload: ↓

CO: ↑ (opp of vol/card shock)

Afterload: ↓ (opp of vol/card shock)

BP: ↓

Organ Perfusion: ↓

21
Q

Systemic Inflamm Response Synd (SIRS) is? (4)

A

response to severe clinical insults:

1) ↑ or ↓ temp
2) HR > 90 bpm
3) Resp > 20 bpm or PaCO2 < 32 mmHg
4) WBC > 12k or < 4k or >10% band

22
Q

Sepsis definition?

Severe Sepsis definition?

Septic Shock definition?

A

Systemic response to infection PLUS ≥ 2 SIRS

Sepsis w/ organ dysfxn, hypoTN or hypoperfusion

Sepsis-induced hypoTN despite adequate resuscitation

23
Q

Sepsis General Variables? (7)

A
Fever > 100.1
Hypothermia < 96.8
HR > 90
Tachypnea
∆ mental state
Significant edema
Hyperglycemia w/o DM
24
Q

Sepsis Inflamm Variables? (4)

A

Leukocytosis > 12k
Leukopenia < 4k
N count w/ > 10% band cells
Plasma C-react Protein or Procalcitionin

25
Q

Sepsis Hemodynamic Variables? (3)

A

Arterial hypoTN w/
SBP < 90
MAP < 70
or SBP ↓ > 40

26
Q

Sepsis Organ Dysfxn Variables? (7)

A
Arterial hypoxemia
Acute oliguria
Cr ↑
Coag
Ileus
Thrombocytopenia
Hyperbilirubinemia
27
Q

Sepsis Tissue Perfusion Variables? (2)

A

Lactic acidosis/Metabolic acidosis

↓ cap refill

28
Q

Multi System Organ Failure includes:

Hepatic?

Renal?

Pulmonary?

Cardiac?

Neuro?

Other?

A

Hepatic: Transaminitis, ↑ bilirubin, ↓ ablumin, coag, NH4

Renal: Acute tubular necrosis, olig/anuria, uremia

Pulmon: ARDS, infection

Card: arrhy, myocard depression

Neuro: mental status -> coma

Other: coag, immune

29
Q

Hyperdynamic vs Hypodynamic Septic Shock?

A

Both: hypoTN, tachycard, tachyp

Hyper: bounding pulse, warm and well perfused extremities, flushed and moist skin

Hypo: thready pulse, cold and poor perfused extrem, pale and dry skin