Exam 3 Flashcards
(70 cards)
Spongy Bone
-Found inside & at the ends of bones
-Has more cavities in it that form a network of bony tissue
-Red blood cells are produced within red bone marrow located in the cavities between the trabeculae
-Red bone marrow forms the structural foundation of spongy bone
-20% of skeletal mass
-Predominant type of bone tissue in the axial skeleton
Compact Bone
-Hard, dense tissue that has less cavities as compared to spongy bone
-Forms the outermost layer of bones
-80% of skeletal mass
-Predominant type of bone tissue in the long bones & appendicular skeleton
Purposes of the Skeletal System
-Offers structural support to the body
-Provides attachments points for muscles & tendons
-Serves as a calcium reservoir
-Houses red bone marrow
Osteoblasts
Build bone in response to demands placed on them
Osteoclasts
Destroy bone to make way for new bone growth and help to maintain blood calcium levels
Estrogen & Testosterone
-Inhibits apoptosis of osteoblasts, increases apoptosis of osteoclasts & stimulates osteoblast activity promoting greater calcium deposition
-Almost 95% of peak bone mass achieved during childhood/adolescence is influenced by estrogen & testosterone
Bone Health in Childhood/Adolescence
-Osteoblast activity outpaces osteoclast activity resulting in longer, stronger, & denser bone
-Continues to the ages of 20 to 30
Bone Health in Early Adulthood
Process slows until osteoclast activity equals osteoblast activity
Bone Health in Middle Age
-Osteoclast activity outpaces osteoblast activity
-Results in a loss of bone tissue predisposing the bone to osteoporosis & risk of fracture
Bone Health in Old Age
Osteoblast activity decreases as the relative proportion of osteoclasts increases resulting in slow bone repair
Why do women have more bone related issues?
-Hormonal changes of menopause & decreased collagen synthesis
-Dramatic drop in estrogen production postmenopausal strips calcium from bone
-Women lose spongy & compact bone at a rate 3-4x faster than men & premenopausal women
-Men have greater peak bone mass
-Less dramatic drop in testosterone later in life
What causes people to lose height?
-Loss of bone mass, bone fracture, & intervertebral disc deterioration
-Decreases in bone mass & deteriorating discs lead to hunchback
Articular Cartilage (hyaline cartilage)
Covers the ends of articulating bones
Synovial Capsule
Two layered joint capsule that surrounds synovial joints
Synovial Joint Layers
-Fibrous Layer (outer)
-Synovial Membrane (inner)
What produces synovial fluid?
The Synovial Membrane
Joints
Exist anywhere two bones meet
Synovial Joints
-Freely moveable joints including hinge and ball and socket joints
-Prone to deterioration & disorder because they articulate
Aging Joints: Water
-Total body water decreases
-Pulls water out of the cartilage pads found between vertebrae (vertebral discs)
-Decreases flexibility & eventually stiffens the spine
Aging Joints: Collagen
-Structural component of cartilage, tendons, & ligaments
-Produce less collagen so articular cartilage begins to thin & wear away
-Joints lose cushioning & lubrication and become stiff & achy
-Ligaments & tendons become stiffer & more brittle decreasing flexibility & movement
Aging Joints: Blood Supply
-Capillary supply to the synovial membrane drops resulting in less synovial fluid produced
-Causes joint stiffness and immobility
-Allows debris & microbes to accumulate in the synovial cavity, further impairing mobility
-Though collagen production begins to slow around age 25, age-related changes in the joints usually aren’t apparent until age 40
What is the most common form of arthritis?
Osteoarthritis
What does osteoarthritis affect & what is it less common in?
-Affects small joints of the fingers, feet, & spine as well as weight bearing joints such as hips & knees
-Less common in wrists, elbows, & shoulders
Adding Stress on Osteoarthritis
-Discomfort develops over years resulting in varying degrees of pain as the joint is used
-Aging, obesity, diabetes, & joint trauma increase likelihood of OA