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Flashcards in Exam 3 Deck (167)
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1

What are the four genes implicated in the pathogenesis of colon cancer? In order?

APC

K-Ras

DCC

p53

2

Cancers caused by Lynch Syndrome?

colorectal

endometrial

ovarian

3

What enzyme does stool Guiac measure?

peroxidase

4

How often should a colonoscopy be done?

10 years

5

How often should a flexible sigmoidoscopy be done? With?

5 years

FOBT every 3 years

6

How often should a high sensitivity FOBT be performed?

every year

7

When should a patient with Crohns or UC have a coloscopy be done? Repeat how often?

8-10 years from their diagnosis

every 1-2 years

8

When should a colonoscopy for Lynch Syndrome be performed?

20-25 years

9

When should a colonoscopy for FAP Syndrome begin?

10-12 years

10

Which nodes would rectal cancer spread to?

inguinal

11

How many nodes should be examined for staging?

15

12

How long should the margins be during resection?

5 cm both sides

13

What does Tis mean?

intra-epithelial

14

What does T1 mean?

muscularis mucosa in to submucosa

15

What does T2 mean?

invades muscularis propria

16

What does T3 mean?

invades pericolorectal tissues

17

What does T4a mean?

penetrates peritoneum

18

What does T4b mean?

invades adjacent organs

19

What is the most common mutated oncogene in panceatic cancer?

Kras

20

What are the two chemicals associated with pancreatic cancer?

β-naphthyline

benzidine

21

How do tumors of the pancreatic head present?

jaundice and weight loss

22

How do pancreatic tumors of the body and tail present?

pain

23

What is the diagnostic modality of choice for pancreatic cancer?

Spiral CT with contrast

24

What type of pancreatic tumors are found with ERCP?

small tumors

25

What is the marker for pancreatic cancer?

CA 19-9

26

Will a pancreatic cancer in the head or the tail present earlier? What type of pancreatic cancer presents in the head?

head

adenocarcinoma

27

Where does pancreatic cancer metastisize?

liver and peritoneum

28

Though modest, what drug has been shown to prolong life in pancreatic cancer?

Gemcitabine

29

What drug works better than gemcitabine for pancreatic cancer?

folfirinox

30

What is the newest drug for pancreatic cancer?

abraxane