Flashcards in Exam 3 Deck (167)
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1
What are the four genes implicated in the pathogenesis of colon cancer? In order?
APC
K-Ras
DCC
p53
2
Cancers caused by Lynch Syndrome?
colorectal
endometrial
ovarian
3
What enzyme does stool Guiac measure?
peroxidase
4
How often should a colonoscopy be done?
10 years
5
How often should a flexible sigmoidoscopy be done? With?
5 years
FOBT every 3 years
6
How often should a high sensitivity FOBT be performed?
every year
7
When should a patient with Crohns or UC have a coloscopy be done? Repeat how often?
8-10 years from their diagnosis
every 1-2 years
8
When should a colonoscopy for Lynch Syndrome be performed?
20-25 years
9
When should a colonoscopy for FAP Syndrome begin?
10-12 years
10
Which nodes would rectal cancer spread to?
inguinal
11
How many nodes should be examined for staging?
15
12
How long should the margins be during resection?
5 cm both sides
13
What does Tis mean?
intra-epithelial
14
What does T1 mean?
muscularis mucosa in to submucosa
15
What does T2 mean?
invades muscularis propria
16
What does T3 mean?
invades pericolorectal tissues
17
What does T4a mean?
penetrates peritoneum
18
What does T4b mean?
invades adjacent organs
19
What is the most common mutated oncogene in panceatic cancer?
Kras
20
What are the two chemicals associated with pancreatic cancer?
β-naphthyline
benzidine
21
How do tumors of the pancreatic head present?
jaundice and weight loss
22
How do pancreatic tumors of the body and tail present?
pain
23
What is the diagnostic modality of choice for pancreatic cancer?
Spiral CT with contrast
24
What type of pancreatic tumors are found with ERCP?
small tumors
25
What is the marker for pancreatic cancer?
CA 19-9
26
Will a pancreatic cancer in the head or the tail present earlier? What type of pancreatic cancer presents in the head?
head
adenocarcinoma
27
Where does pancreatic cancer metastisize?
liver and peritoneum
28
Though modest, what drug has been shown to prolong life in pancreatic cancer?
Gemcitabine
29
What drug works better than gemcitabine for pancreatic cancer?
folfirinox
30
