Exam 3: Cell-cell interactions (Class 1) Flashcards

1
Q

What is an emergent property?

A

A property that a collection/complex system has, but the individual members do not have

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2
Q

What is epithelial tissue?

A

A sheet of cells that covers a body surface or lines a body cavity

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3
Q

In order for multicellularity to occur…

A

cells have to be bound together

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4
Q

Sequence of connections in the epithelium

A

Epithelial tissue –> basal lamina –> connective tissue

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5
Q

What bears the stresses of tension and compression

A

The extracellular matrix

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6
Q

What transmits stresses from cell to cell

A

Cytoskeletal filaments anchored to cell-matrix and cell-cell adhesion sites

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7
Q

What is the condition where mutations in proteins cause epithelia to not adhere to the basal lamina?

A

Epidermolysis Bullosa

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8
Q

3 types of cell-cell attachments

A
  1. tight junctions
  2. desmosomes
  3. gap junctions
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9
Q

Function of tight junctions

A

seal cells together

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10
Q

Function of desmosomes

A

connect the cytoskeletons of cells

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11
Q

Function of gap junctions

A

act as channels between cells

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12
Q

What are tight junctions composed of

A

Specialized proteins

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13
Q

Where are tight junctions located

A

In the plasma membranes of adjacent animal cells

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14
Q

How do the proteins in tight junctions orient themselves?

A

They line up and bind to each other

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15
Q

Where do the proteins in tight junctions bind?

A

Between the two plasma membranes

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16
Q

What does the stitching of the two cells in tight junctions form?

A

A watertight seal

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17
Q

Which types of tissues are desmosomes common in?

A

Epithelial and muscle

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18
Q

What do the proteins of desmosomes bind to? (2 answers)

A
  1. to each other
  2. to proteins that anchor intermediate filaments
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19
Q

What are the adhesion proteins in desmosomes?

20
Q

What is selective adhesion in adult cells?

A

The way that adult cells attach to each other selectively, attach to the same kind of cell

21
Q

What are plant cells connected by?

A

Plasmodesmata

22
Q

In animal tissues, how do gap junctions connect adjacent cells?

A

Forming channels

23
Q

What five things bind adjacent cells to each other?

A
  1. middle lamella
  2. continuous ecm
  3. tight junctions
  4. desmosomes
  5. cadherins
24
Q

What allows adjacent plant cells to communicate?

A

Plasmodesmata

25
What allows adjacent animal cells to communicate?
Gap junctions
26
What tissue in the human body needs gap junctions, desmosomes, and tight junctions?
Cardiac tissue
27
What is decellularization?
Removal of cells to isolate the extracellular matrix scaffold
28
What makes up the ECM? (3 things)
1. GAGs 2. Proteoglycans 3. Fibrous proteins
29
What are the 4 types of fibrous proteins to know?
1. Laminin 2. Fibronectin 3. Collagens 4. Elastin
30
What is the function of GAGs?
Gel-like squishiness and protection
31
GAGs are highly ____ charged
negatively
32
What are proteoglycans?
A polysaccharide (GAG) + a core protein
33
What is the function of laminin and fibronectin
Connect cells to the ECM and organize components in the ECM
34
What are the functions of collagens
Provides tensile strength
35
What is the function of elastin
Stretch and recoil
36
What is the sequence of how things are attached from cytoskeleton to ECM?
Actin --> integrin --> fibronectins --> collagen
37
What is the cell wall made of?
Long strands of cellulose
38
What are the long strands of cellulose in the cell wall bundled into?
Microfibrils
39
What do the microfibrils in the cell wall form?
A crisscrossed network
40
What are the two types of cell walls?
Primary and secondary
41
Where is the primary cell wall?
Between newly made cells
42
The primary cell wall is __ and __
Thin and flexible
43
What is the primary cell wall mainly made of?
Cellulose
44
What keeps the primary cell wall moist?
Pectins and glycans
45
Which cell wall defines the shape of the cell?
Primary
46
Where is the secondary cell wall?
Between the plasma membrane and the primary cell wall
47
What are the three layers between adjacent plant cells?
1. primary cell wall of one plant cell 2. middle lamella 3. primary cell wall of the other plant cell