Exam 3 Concepts

Question 1

embryonic stem cells

Answer 1

derived from fetus
can differentiate into any cell (pluripotent)
indefinite proliferation

Question 2

adult stem cells

Answer 2

from self so rejection is less likely

don’t have to destroy embryos

Question 3

induced pluripotent

Answer 3

pluripotent
less likely rejection because from self
indefinite proliferation
greater chance of cancer induction

Question 4

retrovirus

Answer 4

can produce insertional mutagenesis

provides means of introducing gene of interest into population of cells

Question 5

adenovirus

Answer 5

remains extrachromosomal thereby eliminating insertional mutagenesis
can accommodate large genes
can provide excessive immune response

Question 6

adeno-related virus

Answer 6

remains extrachromosomal less likely to provoke immune response
can only accommodate small DNA pieces

Question 7

lentivirus

Answer 7

provides means of introducing gene of interest into population of cells
less prone to insertional mutagenesis than other retroviruses
can still produce insertional mutation